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Effect of malaria in countries
Sickle Cell Anemia Research Paper
Sickle cell anemia introduction research paper
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B1.1 Where do you think you’ll find that the most villagers are dying from sickle-cell anemia? Explain.
Most villagers that are dying from sickle-cell anemia will come from the villagers at the very wet regions where there are many mosquitoes. The simulation shows that the malaria death for very wet regions rate is 0.2, that is the highest number compared to other regions. It is because there are many mosquitos in that area, so that area might be where malaria has long been endemic. Because of that, the villagers in those very wet regions have evolved dozens of chemical as defenses against malaria and the sickle cell is one of them (anti-malarial). Natural selection acts so that people with sickle cell allele are more common in those very wet regions as they survive and reproduce better in the environment where malaria is endemic, especially those people with heterozygous sickle cell allele (HbA/HbS) as it acts as ‘shield’ that protect them from dying from malarial disease and also sickle cell disease. However, those who have sickle cell allele especially the homozygous for the
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Explain. Yes, the sickle cell allele will disappear but only at the dry area where there are no mosquitoes. It is because, if we applying the natural selection theory, people with sickle cell will not have any advantage at environment that do not have or have very little cases of malaria, like the dry area that have no mosquitoes. People with sickle cell anemia at the dry area will die from the sickle cell disease, as the antimalarial properties of the sickle cell is not an advantage at the dry environment, including those that are sickle cell disease carrier. So, as the time goes by, the population with sickle cell anemia will die out and disappears, because those that did not have sickle cell allele will survive and reproduce better compared to those who have the sickle cell
On Sunday, a nurse on a medical/surgical floor in a large private hospital is assigned as the primary nurse to a woman who was just admitted. The woman’s testing begins on Monday and the primary nurse does not have work for the next few days. The nurse returns on Saturday and goes over the woman’s charts. The nurse discovers that the woman has chronic lymphocytic leukemia and is being treated for the disease. After approaching the woman the nurse realizes that the woman is unaware of her diagnoses as she asks the nurse when she will be able to return to work. The nurse explains that she has not yet spoken with the physician and will get back to her once she has done so. On your way back to the nurses' station, one of the woman's two daughters approaches the nurse and urges the nurse to assure her mother that there is no reason for concern. The daughter explains that her mother has just been through a painful divorce and
This module of study has focused on many aspects of human health, anatomy, and the disease process. It has included such topics as the human organ systems, the mechanism of disease and the resulting disruption of homeostasis, the integumentary system, and the musculoskeletal system. The following case studies explore how burn classification will affect treatment, how joint injuries can disrupt mobility, and last, how a sedentary lifestyle can contribute to a decline in a person’s health status. The importance of understanding disease and knowing when to seek treatment is the first step toward enjoying a balanced and healthy life.
Malaria survives on healthy red-blood cells and carriers do not have a lot of healthy red-blood cells. Similarly to how those with hemochromatosis starved the bubonic plague of iron, sickle cell anemia carriers starve malaria of red-blood cells. The proactive effect of malaria only works on those who have one copy of sickle cell anemia and not the actual illness. If one has sickle cell anemia, one is more likely to get malaria. Nonetheless, malaria is such a vicious disease that anything that can aid in the fight against it and towards survival and reproduction is helpful.
1. Sickle Cell Disease is life-threatening and has a risk of of causing depression. In this study I examine the experiences that Sickle Cell patients go through specifically at emergency healthcare facilities to find out if there are any negative stigmatizations surrounding this disease. There may be judgments that are made about these patients from healthcare professionals when they seek drugs for their pain relief that may cause the stigmatization to occur. I will also investigate why individuals that have Sickle Cell Disease experience longer waiting times at emergency healthcare facilities and the lack of control they may have over their care regime.
In the continent Africa, about 1 in 100 individuals develops this disease. We ask ourselves why is the frequency of a potentially fatal disease so much higher in Africa? The answer is related to another deadly disease, which is called malaria. Chills, fever, vomiting, and severe headaches characterize malaria (GENETICS Sickle Cell Case Study. (n.d.). 2000, October 19). Malaria is caused by a disgusting parasite called Plasmodium that is transmitted to humans by mosquitos. When the malaria parasites invade the bloodstream, the red blood cells that contain defective hemoglobin get sickle cell out and die (Facts About Sickle Cell Disease. 2014, January 16). This helps protect the individual with Sickle Cell Anemia from an infection of malaria. As you can see, this is why a variety of areas in the world has a high rate of malaria, such as
Sickle Cell Disease (SCD) (also known as Sickle Cell Disorder or Sickle Cell Anemia) is an inherited blood disorder where the red blood cells have abnormal sickle-shaped hemoglobin S (HbS) called sickle haemoglobin (National Heart Lungs and Blood Institute (NHLBI), 2015). The disease, according to medical sciences, is inherited from both parents as part of their genetic makeup and is usually caused by some abnormalities in haemoglobin which is a protein in red blood cells that conveys oxygen through the body. Whereas normal red blood cells are round, in people with sickle cell anemia, a defective substance in red blood cells changes the shape of the cells. The normal haemoglobin called haemoglobin A (HbA) is replaced by HbS which later becomes
Having an inherited disease like sickle cell anemia takes a life-long of treatments and preventions of complications that comes with being diagnosed with sickle cell anemia. Many people have lived a long time while dealing with the disease because of the on-going care being provided to keep patients as healthy as possible. Knowing that both male and female have the sickle cell trait can prevent having a child with the sickle cell disease. From the help of the parents, doctors and medicine, sickle cell patients don’t have to deal with the pressure of living with a life threatening disease.
In the United States today, many aspects of health are very segregated. This form of separation is referred to as silos. Animal, human, and environmental health are separated into these silos. Experts in these fields rarely work together or collaborate. The majority of research, funding, and resources are separated in to the three disciplines. The solution to this issue is the concept of “One Health”. One Health acknowledges the connectivity of all aspects of health. By working together, it is possible to detect outbreaks of disease earlier and save many more lives. One Health has made a dramatic influence on infectious disease prevention, detection, and treatment. Although there has been some advancements, there is still much
During a short break of solitude from studying, I explored and came across that the environment in which most African Americans reside in has a high occurrence of malaria virus. The malaria virus disease is contagious and when it contaminates someone with sickle cell traits, it cannot survive on the external part of the human body so therefore the individual doesn’t develop the deadly malaria virus. While looking further into our class textbook on Human Genetics 11th Edition by Ricki Lewis, and this issue of sickle-cell among the African Americans, I
Sickle-cell anemia is a genetic disorder that makes your body produce red blood cells that are abnormal in shape. This disease is also widely known as hemoglobin SS disease. Unlike normal red blood cells, sickle cells are rigid and tenacious. Due to their shape and rigidness, they can block blood flow. In turn, this could cause organ damage to the body. Sickle cells are also fragile and die very easily due to the fact sickle cells have a lifespan of twenty days instead of the normal one hundred and twenty days for normal red blood cells.This causes the body to have a lower blood cell count, hence the name anemia in sickle cell anemia.
Unlike normal red blood cells that last about 4 months in the bloodstream, fragile sickle cells break down after only about 10 to 20 days, which usually causes anemia. Anemia (pronounced: uh-nee-mee-uh) is what happens when the body's number of red blood cells (or amount of hemoglobin) falls below normal. People who are anemic often feel weak and tire more easily.
Sickle cell was first discovered by Dr. Ernest irons that was a hospital intern who look over a patients cell which seem to be different he called them “sickle cell shaped”. Sickle cell is know as a negro inherited diseases which is incorrect not only African Americans have this diseases. Many other races are effect by this diseases and regions all over the world such as India, Mediterranean countries, South American. In this case sickle disease work kind of like vaccination for malaria another diseases, this is the most common inherited disease in American. Anyone who has sickle trait and have a baby with someone who has the trait also can bring a baby into the world the world with SCD.
...creases, therefore speeding the sickling process. Sickle cells also have a shorter life span (10 - 20 days) than normal red blood cells (90 - 120 days). Every day the body produces new red blood cells to replace old ones, but sickle cells become destroyed so fast that the body cannot keep up. The red blood cell count drops, which results in anemia. This gives sickle cell disease its more common name, sickle cell anemia.
Sickle Cell Anemia seems to be one of the hardest conditions to live with due to the severity of its symptoms and it can be an encumbrance to everyday life. Although this condition is hard to live with, it is possible to live with it. Thanks to the twenty-first century advancements, there is great medical care available to patients and many other resources and support groups to help families through this harsh reality of living with sickle cell. Perhaps one day there will be a readily available cure for this horrible disease. Until then, a patient with sickle cell should have a support system and take care to live a healthy life so that they can live their life to the fullest.
Unfortunately this disease is passed down from the parent to the child genetically. “If both parents have sickle cell trait (each have one normal hemoglobin gene and one sickle cell gene), the child has a 50% chance of inheriting sickle cell trait (one normal gene, one sickle cell gene), 25% chance of inheriting sickle cell disease (two sickle cell genes), and 25% chance of not inheriting either the trait or the disease (two normal genes) (Harvey)”.