The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged.This is what causes the problems of sickle cell disease.As to this day there is really no cure for sickle cell disease.Red blood cells take oxygen from the air we breathe into our lungs to all parts of the body. Oxygen is carried in red blood cells by a substance called hemoglobin(Hemoglobin – is the main substance of the red blood cell.
Abstract Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia. Older children and adults with sickle cell disease may experience a few complications, or have a pattern of ongoing problems that shorten their lives. The most common and serious complications of sickle cell disease are anemia, pain, fatigue, and organ failure.
Sickle cell anemia primarily affects people with African, Mediterranean, Middle Eastern, and Indian ancestry (Learn genetics, 2010; NHLBI, n.d.; Vorvick et al., 2010). Sickle cell anemia occurs when a person inherits two sickle cell gene, one from each parent, that cause the red blood cells to change and become crescent shaped. The underlying problem involves hemoglobin, a component of the red blood cells. Hemoglobin is a protein molecule in red blood cells that carries oxygen from the lungs to the body’s tissues and returns carbon dioxide from the tissues to the lungs (Nabili, 2008, para. 1).
Red blood cells usually live for 120 days before they need to be replaced by new ones. However, sickle cells die off after ten to twenty days. Another symptom of sickle cell anemia is episodes of pain. Episodes of pain are one of the major symptoms of sickle cell anemia. The pain develops because sickle-shaped red blood cells block the flow through tiny blood vessels to your abdomen, joints, and chest.
Red blood cells hold haemoglobin which carries oxygen and takes out carbon dioxide to and from the cells throughout different organs of the body. Platelets help poke holes in the blood vessels and form clots just as blood vessels are corrupted or damaged (What is Leukemia? par. 4 & 5). When these cells in the bone marrow divide uncontrollably, they form more white blood cells than required and thus, lead to leukemia cancer.
Red blood cells are made in the spongy bone marrow inside the larger bones in the body. Also, red blood cells are being made every day and are able to live around 120 days in your bloodstream carrying oxygen and removing carbon dioxide before dying. A sickle cell onl... ... middle of paper ... ...ailable is a blood transfusion. Blood transfusions are used to prevent people with worsening cases from having fatal symptoms. The side effects to blood transfusions are: allergic reactions, and increased risk of hepatitis and HIV.
Meanwhile, the bone marrow, where red blood cells are made, pitches in by making more cells. It can't keep up with the destruction, though, so the total number of red blood cells drops to a low level and the body becomes anemic. ("Anemic" is the medical word for having a low number of red blood cells.) What is sickle cell anemia? Sickle cell anemia is an inherited disease of red blood cells.
They grew up, had their own children and ended up passing the gene for sickle cell anemia onto their offspring. This disease is a hereditary blood disorder that affects the red blood cell. Red blood cells contain a protein called hemoglobin which transports oxygen from your lungs to every part of your body. Hemoglobin's oxygen carrying ability is essential for living but if there is a structural defect on the pigmented molecule, it can be fatal. When a normal red blood cell distributes its oxygen, it has a disc shape.
If the spleen is enlarged or diseased, it could remove more red blood cells than necessary which would lead to having anemia. Also if too many red blood cells are destroyed that can lead to sickle cell ... ... middle of paper ... ...ies which will decrease their amount of physical activity Conclusion Anemia is a condition that can develop in anyone of any age. It can range from being minor or warning signs of something more serious. When a person lacks enough healthy red blood cells anemia can occur. Anemia can be treated with medication and changes in one’s diet.
As earlier mentioned, red blood cell contain hemoglobin. Hemoglobin’s carry two different types of protein chains: the alpha globin and beta globin. The body of a person with Thalassemia will not function well due to inadequate or abnormal production of alpha or beta protein chain which in turn, affects red blood cells performance of their functions. National Heart, Lung and Blood Institute (2013) ex... ... middle of paper ... ...onditions/thalassemia/basics/symptoms/con-20030316?p=1 Medical News Today (2014, July 17). What Is Thalassemia?