Analysis Of Parkinson 's Disease, Population Above 70 Years Essay

Analysis Of Parkinson 's Disease, Population Above 70 Years Essay

Length: 1597 words (4.6 double-spaced pages)

Rating: Better Essays

Open Document

Essay Preview

People above 70 years

Justification: In Parkinson’s disease, population above 70 years has more than 50 % prevalence of dementia. The study subjects above 70 years will be more likely to have underlying cognitive decline and varying degrees of dementia. To ensure the validity of our outcome measure we exclude the population that has a higher prevalence of our outcome measure and raise questions about dementia that is our outcome measure and as evident from epidemiological studies people who already have PD dementia have decreased survival time less than five years.1,2

• Parkinson’s disease patients with severe dyskinesia (score > 2 Modified Dyskinesia Scale)

Justification: It may raise ethical issues if subjects with more severe disease are included in the study. It may add additional hardships to their suffering. Also, during their visit to research center more safety measures will need to be taken. They tend to be more unstable in their movements, and their gait and risk of falling is high and may lead to liability issues.

• Evidence (physician diagnosed) of atypical Parkinson syndromes (e.g. Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Cortical-Basal Degeneration (CBD); other causes of dementia based on clinical grounds (e.g. Alzheimer’s disease, vascular dementia, frontotemporal dementia, Creutzfeldt-Jakob disease, Huntington’s Disease);

• People with acute medical problems (e.g. myocardial infarction with congestive heart failure and ejection fraction less than 35, uncontrolled diabetes (HgA1c > 11 and showing no improvement while taking Insulin), advanced Osteoarthritis (people who did not get more than 70% relief from > 3 intra-articular steroid injection)

Justification: Myocardial infarctio...

... middle of paper ...

...res can indicate severe (≤9 points), moderate (10–18 points) or mild (19–23 points) cognitive impairment.

• Subjects will be evaluated based on MMS (Mini-mental state examination) every one year.

•Any person who develops cognitive impairment within one year of diagnosis of Parkinson 's disease.

•Participant with the onset of cognitive impairment before Parkinson 's disease diagnosis with the onset of cognitive impairment before Parkinson’s disease will be excluded from the study, as the diagnosis would be Lewy body dementia.

Ensuring Confidentiality:

•The complete data is password protected.

•The data is accessible only to investigators who are involved in the study.

•The Identity-names of the subjects will be given a designated number, and the document will be strictly accessible only by the Investigators.

•Digital signature can be used for data protection.

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Essay on Brain Diseases: Alzheimer’s Disease, Parkinson’s Disease

- INTRODUCTION Brain, a complex organ, is vital for all of the body’s function. Any somatic and genetic variation in the brain can lead to various pathological and degenerative conditions like Alzheimer’s disease, Parkinson’s disease, Pick’s disease, Multiple Sclerosis etc. Injuries to the brain have a high tendency to perturb massive areas of the organ which in turn lead to defects in memory, cognition, learning, personality, and various other fundamental functions of the body. Injury can be a physical damage to the brain or the closed head injuries like the stroke, ischemia, and sudden blow, overdose of various drugs or the neurotoxins....   [tags: drugs, treatment]

Better Essays
2354 words (6.7 pages)

Essay on Depressive Symptoms in Population Affected by PD

- Introduction. Some neuron-circuits, provide link of frontal cortex and basal ganglia. Basal ganglia involved in movement, attention, and memory processes. Knowing this, could clarify why disorders of the basal ganglia, are characterised by abnormalities of above mentioned processes (Ring & Serra-Mestres 2002). Parkinson’s disease (PD) is a degenerative disorder of basal ganglia function, which characterised by progressive destruction of the nigrostriatal pathway, thus ensuing decrease in striatal concentrations of neurotransmitter called dopamine (Porth et al 2005)....   [tags: Parkinson's Disease, Treatment, Depression]

Better Essays
1705 words (4.9 pages)

Parkinson 's Disease And Its Effects Essay

- Parkinson’s Disease Parkinson’s disease has become front page news as of late. It has caught the attention of many due to its unrestricted and devastating effects. People from all walks of life can suffer from the disease. It has no economic, social, or religious boundaries. Well known celebrities such as Muhammad Ali, Michael J. Fox, Estelle Getty, Billy Graham, Janet Reno, Pope John Paul II, and Johnny Cash, among many others, have fallen victim to this debilitating ailment. Because Parkinson’s disease is “one of the most common neurologic disorders of older adults” (Ignatavicius & Workman, 2016, p....   [tags: Parkinson's disease, Dopamine, Neurology]

Better Essays
2193 words (6.3 pages)

Symptoms And Symptoms Of Parkinson 's Disease Essay

- Running head: PARKINSON’S DISEASE Parkinson’s Disease Roy Franco Brown Mackie College Care of Adults II Parkinson’s disease Parkinson’s disease is the second most common neurological disease after Alzheimer’s (Copstead, 1132). It may be described as idiopathic or acquired. It is generally not life threatening, however is incurable. Briefly we will discuss the pathology, etiology, signs and symptoms, current treatment trends and future potential treatment regimens. Parkinson’s disease is a nervous system disorder that becomes progressive and affects the motor functions and non-motor functions (Copstead, 1132)....   [tags: Parkinson's disease, Dopamine, Neurology]

Better Essays
945 words (2.7 pages)

Essay on Parkinson 's Disease Is A Serious Disease

- Have you or anyone in your family experienced unusual tremors in your head or any part of your body. Has moving become harder everyday. Do you feel your bones stiffen and feel as if your unbalanced. If so then you may be experiencing the intial effects of Parkinson’s disease. Originally called “Shaking Palsy” due to body tremors, Parkinson’s disease is a progressive neurological disorder of the central nervous system that affects movement. Named by Dr. James Parkinson, Parkinson’s disease is a very serious disease....   [tags: Parkinson's disease, Dopamine]

Better Essays
773 words (2.2 pages)

Diagnosis Of Parkinson 's Disease Essay

- Overall explanation Parkinson’s disease (PD) is a neurodegenerative brain disorder that develops slowly in most of the patients. Most of them can be alive for years after getting Parkinson’ disease. PD occurs because of a low level of dopamine inside the brain and people will find it difficult to move without dopamine. Currently, there is no specific method to cure Parkinson and nobody knows exactly about why it happens. PD will not cause people to die directly, but the condition will become severer with times.The rate of having Parkinson is 1/500 and most people get PD at the age of 50 but some get it earlier....   [tags: Parkinson's disease, Dopamine]

Better Essays
1440 words (4.1 pages)

Parkinson 's Disease ( Pd ) Essays

- Parkinson 's disease (PD) is a neurodegenerative brain disorder that develop slowly in most people. Most people 's symptoms take years to develop, and they live for years with the disease. Most people with PD take years to develop symptoms, and could live years with the disease. Normally, there are brain cells (neurons) in the human brain that produce dopamine. These neurons concentrate in a particular area of the brain, called the substantia nigra. Dopamine is a chemical that send messages between the substantia nigra and other parts of the brain to control movements of the human body....   [tags: Parkinson's disease, Dopamine, Substantia nigra]

Better Essays
1148 words (3.3 pages)

Parkinson 's Disease : Symptoms And Treatment Essay

- Parkinson 's disease is a chronic progressive neurological disorder in which cells are slowly lost in the brain over the years. The fact that cells are lost makes it a neurodegenerative disorder fitting in the same category as Alzheimer disease. A person with Parkinson’s disease can also experience a wide range of physical and psychological symptoms, including depression, constipation, problems sleeping (insomnia), loss of sense of smell (anosmia) and memory problems. () The three main symptoms of Parkinson’s disease are: - Tremor (involuntary shaking of particular parts of the body) - Slow movement (Bradykinesia) - Stiff and inflexible muscles () Parkinson 's disease usually develops late...   [tags: Parkinson's disease, Dopamine, Carbidopa]

Better Essays
1000 words (2.9 pages)

Symptoms And Symptoms Of Parkinson 's Disease Essay

- Parkinson’s disease or (PD) is a crippling neurological disorder that negatively affects the body over long periods of time. PD can affect anyone, from famous people like Mohamed Ali and Michael J Fox to everyday average person. At this time, there are no specific diagnostic criteria for PD. An examination of the disease can only be made only after the person has developed symptoms. This disease will debilitate an individual within five stages. These different stages of the disease will at often times take years to manifest....   [tags: Parkinson's disease, Dopamine, Neurology]

Better Essays
938 words (2.7 pages)

Essay on Parkinson’s Disease

- Parkinson’s Disease is known as one of the most common progressive and chronic neurodegenerative disorders. It belongs to a group of conditions known as movement disorders. Parkinson disease is a component of hypokinetic disorder because it causes a decreased in bodily movement. It affects people who are usually over the age of 50. It can impair an individual motor as well as non-motor function. Some of the primary symptoms of Parkinson’s disease are characterized by tremors or trembling in hands, legs and arms....   [tags: Parkinson’s Disease]

Better Essays
1450 words (4.1 pages)