The skeletal system includes the osseous tissues of the body and the connective tissues that stabilize or interconnect the individual bones. The bone is a dynamic tissue. Throughout the lifespan, bone adjusts to the physiologic and mechanical demands placed on it by the processes of growth and remodeling. Bone serves the organism at multiple levels: As a system, bones permit the organism to locomote effectively and to maintain posture by bearing loads without deformation, by providing rigid attachment sites for muscles and acting as a system of levers to amplify small movements. As an organ, bones protect the viscera and house the hemopoietic tissue (red marrow).
Introduction The term ‘bone’ refers to a group of materials which plays a significant role in the human body (Bauer, Thomas W. MD, PhD and Muschler 2000). They provide the physical support which forms the exoskeleton of the vertebrates. Though they function to move, support and protect the delicate parts of the body they also function as the reservoirs of ions and lipids and they also serve to yield the blood cells in the marrow cavities (Lutton, Read and Trau 2001) Bone structure Bones are composite materials with highly complex structure made up of fibrous proteins, type 1 collagen which is surrounded and made harder by the presence of calcium phosphates (hydroxyapatite, Hap(Ca10(PO4)6OH2)) which acts as a strong filling. (Currey 1932). Bone is made up of nano-composite structure which provides the excellent mechanical properties.
Vacuum‐assisted infiltration of chitosan or polycaprolactone as a structural reinforcement for sintered cancellous bovine bone graft. Journal of Biomedical Materials Research Part A. 2012;100(10):2581-92. 5. Sauer N, Simson L. Clarifying the role of forensic anthropologists in death investigations.
Our anatomical skeleton can be considered the underlying base that allows us to functionally support ourselves in everyday activity. Harnessing the weight of our internal organs, muscle, and all other physiological units, the skeleton is a crucial component to human physiology and function. Our bones specifically are unique in nature, as over time, they reconstruct themselves in a process where cells called osteoblasts regulate bone formation whilst the precursor cells called osteoclasts regulate reabsorption of minerals such as Calcium and Vitamin D (Pierre, 1998). What happens when this structural basis, being our bony skeleton, deteriorates and becomes brittle? How will this affect your everyday life?
The aetiology of osteosarcoma is unclear. However, suggested factors include trauma, pre-existing diseases, rapid bone growth, carcinogens, radiation exposure and hereditary disorders (e.g hereditary retinoblastoma and the Li-Fraumeni cancer family syndrome) (Gaeta, 1988). Osteo... ... middle of paper ... ...lin, D. C. (1975). Pathology of Osteosarcoma. Clinical orthpaedics and related research, 111, 23-32.
The skeletal system consists of 206 bones and has other body attachments that assist in connecting them which are tendons, ligaments, and cartilage. The skeletal system provides vital functions for the human body. The functions this system provides are support, movement, protection, blood cell production, storage for calcium and endocrine regulation. Bone serves as the basic unit of the human skeletal system. Ossification is characterized as a process that produces new bone.
Osteonecrosis of the jaw and the role of bisphosphonates: A critical review. The American Journal of Medicine, 122(2S), 33-45. V.M. Cartsos, S. Zhu and A.I. Zavras,.