Case Study Osteoporosis

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Individual Brainstorming:
• Is this disease genetic?
• Is calcium really good for bones?
• What prevents osteoporosis?
• How do you treat osteoporosis?

Case Study Questions:
Marissa- Scenario A
1. Bones are dense and provide support and structure to the body. The two types of bones is compact and spongy bones. Compact bones are dense and tough. Spongy bones are not as dense and are flexable. Bone remodeling occurs n 120-day cycles. Over the first 20 days resorption by osteoclasts occurs. Osteoclasts release proteases, clears away damaged bone, and releases matrix-bound growth factors. Bone formation occurs by osteoblasts over the last 100 days. Osteoblasts fill in bone cavity with bone matrix.

2. Calcium helps make bones strong and dense. Calcium is not made in the body so the body has to get it from the bones. When calcium is low bones will release less calcium into the blood stream.

3. The body controls calcium levels in the bones and blood through parathyroid hormone and calcitonin. PTH is released in the blood to stimulate osteocytes, which causes bone to breakdown. In turn this releases calcium when levels are low in the blood stream.

4. When new bone is not being readily produced or the body is reabsorbing too much old bone causes osteoporosis. During this time bone remodeling is not occurring when the bone becomes damaged. Lack of bone remodeling causes the bone to continue to breakdown. This breakdown may cause stress and fractures.

5. Scientists know that low BMD genes can have an increase for osteoporotic fractures. Mutations of the estrogen ER gene can cause osteoporosis; as well COLIA1 and COLIA2 gene mutations can result in severe forms of osteoporosis. The most reliable knowledge is the identification of BMD r...

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...is flexibility with stretches, T'ai chi, ad yoga. All of these exercises prevents osteoporosis, builds muscle, endurance, and thickness of bones.
Jeremy mentioned taking steroids to help him bulk up. Steroids are natural or synthetic compounds used to increase muscle mass through hormones. Although, steroids increases muscle mass it breakdown bones and delays bone remodeling. It also increases the risk of osteoporosis by making it difficult for calcium to be absorbed into the blood stream.
Jeremy's activities can ultimately affect his bone health. Through exercise he can increase his peak bone mass and prevent osteoporosis. If he changed his diet from heavily drinking to increasing his calcium amounts his bone health will become stronger. Lastly, Jeremy should avoid using steroids and rely on exercise and his diet to gain muscles and get stronger, healthier bones.

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