The Relationship Between Ketosis And Infectious Diseases

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The Relationship between Ketosis and Infectious Diseases

Ketosis is a metabolic disease that occurs when cows are in negative energy balance due to a decrease in DMI prior to parturition that does not increase at the same rate as energy requirements for lactation. This metabolic stress results in altered nutrient metabolism and immune system dysfunction. This processing of metabolic energy resources causes ketone bodies to accumulate in bodily fluids such as milk, blood and urine . While clinical cases of ketosis are generally less that 5%, some studies estimate the incidence of subclinical ketosis at up to 40% . The disease is more common in regions managed for intensive production . As a metabolic disease ketosis is linked to infectious diseases such as mastitis by causing immune system depression, this means that ketosis has the potential in incur huge costs and other health problems on your dairy operation.
Periparturient Disorders …show more content…

This decrease in DMI causes a shortage of metabolic glucose precursors needed for milk synthesis, resulting in a negative energy balance. Periparturient disorders that can be responsible for ketosis include calving difficulty, retained placenta, endometritis and milk fever . Since ketosis depresses the immune system, cows are more susceptible to infectious diseases such as mastitis, metritis and endometritis, forming a risk cycle that will continue unless appropriate steps are taken to break the

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