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Effects of steroids on the human body
Effects of steroid use and abuse on the body
Effects of steroids on the human body
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Introduction:
Striae distensae, commonly referred to as ‘stretch marks’, is an extremely common skin condition characterized by parallel dermal scaring. The scarring is aligned perpendicular to the direction of skin tension and accompanied by epidermal atrophy. According to Elsaie, Maumann & Lofty (2009), striae distensae are two and a half times as frequent in women and affect up to 90% of pregnant women. and the abdomen and breasts during pregnancy.
Anatomical Basis and Function:
Gilmore and Vaughn (2012) state that the maturation of striae is similar to that of scar formation. Their evolution is characterized by three distinct phases. The initial acute stage, striae rubra, present as flattened, thinned skin with a pink hue that are sometimes accompanied by an itching sensation. When these early lesions are inspected under a light microscope, fine elastic fibers predominate throughout the dermis in association with thick and tortuous fibers toward the periphery. This inflammatory phase involves changes dermal oedema, perivascular lymphocyte cuffing, and an associated increase in the glycosaminoglycan content of the dermis. Collagen bands on the upper third of the reticular dermis are stretched and aligned parallel to the surface of the skin. The content of an integral component of these elastic fibres, fibrillin microfibrils, is reduced. Striae rubra evolve into a subacute stage where they increase in length and acquire a darker purple color. This phase generally progresses onto the later, chronic phase known as striae alba. Striae alba are characterized by hypopigmentation, loss of appendages, atrophic epidermal atrophy, and densely packed regions of thin eosinophilic collagen bundles aligned horizontal and parallel to the ...
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...ermal matrix substance.
Striae induced by prolonged systemic steroid use are usually larger and wider than other phenotypes of striae, and they involve widespread areas, occasionally including the face.
Striae secondary to topical steroid use are usually related to enhanced potency of the steroids when using occlusive plastic wraps. They usually affect the flexures and may become less visible if the offending treatment is withheld early enough.
(http://emedicine.medscape.com/article/1074868-clinical#a0217)
Conclusion:
Though striae distensae does not cause any significant medical problem they can be detrimental in that their presence can cause significant cosmetic concern to those affected. Various treatments, including laser and light sources have been used in an attempt to alleviate striae distensae, but no definite working treatment has been established.
To begin we will look at the integumentary system and its entire multitude of functions. The main components of the integumentary system are the skin, hair, nails, glands and nerves. For the purpose of this paper we will focus mainly on the levels of the skin and their functions. While the integumentary
Arch Dermatol. 2007;143(1):124–125. Puchenkova, S. G. (1996). "
Barone, Eugene J., Judson C. Jones, and Joann E. Schaefer. "Hidradenitis Suppurativa." Skin Disorders. Philadelphia: Lippincott Williams & Wilkins, 2000. 21-25. Print.
Not all attributes are obvious for every situation. The lion's share of instances of OI (conceivably 85-90 %) are created by a predominant change in a quality coding for sort I collagen (Types I, II, III, and IV in the accompanying rundown). Sorts VII and VIII are recently recognized structures that are acquired in a passive way. The qualities bringing about these two sorts have been recognized. Sorts V and VI don't have a sort 1 collagen change, however the qualities bringing about them have not yet been recognized. The general components of each referred to sort of OI are as per the
One way steroids affect players is the effect on the mind and mental health of users. When baseball players take steroids, they put their bodies at risk. The risks include psychiatric symptoms such as bipolar disorder (Mitchell 55). Studies have shown that if baseball players get involved with steroids, there is strong chance they will experience symptoms like bipolar disorder or severe depression. Steroids also affect the cardiovascular system. They can cause heart attacks and increased or decreased cholesterol levels, and also cause the heart to become enlarged (Mitchell 55). The cardiovascular system faces tragic effects when people decide to use steroids. The liver is affected by steroids also, as the liver can become impaired, become cancerous, and thus cause skin to yellow (Mitchell 55). The f...
It regulates the ratio between epithelial cells and collagen fibers as well as changes in their morphology. The imbalance of collagen metabolism and its arrangement is attributed to many factors which result in increased synthesis of collagen by fibroblasts and myofibroblasts, which in turn inhibit the activity of collagenase, leading to extensive scar hyperplasia. Matrix changes, mainly changes in fibronectin and mucopolysaccharides, result in scar stiffness. MEBO Scar Ointment can accelerate the re-arrangement of twisted collagen andreduce proliferation of fibroblasts, thus restricting scar hyperplasia. [11,13,14,15 ,21] The accumulation and synthesis of mucopolysaccharide can also be reduced once local tissues are compressed, thus reducing generation of collagen and the corresponding scar tissue. [11] Moreover, massaging the MEBO Scar ointment onto old scars can potentially reduce blood supply within scars, decrease synthesis of collagenous fiber, and,reduce α2-M (alpha 2-macroglobulin) globulin of collagenase in serum which facilitates collagenase activity and speeds up disintegration of collagen in old scars,this facility by applying MEBO scar ointment .
Anabolic steroids are drugs derived from the male hormone testosterone. They promote muscle growth and increase lean body mass. Although anabolic steroids have many approved medical uses, some athletes and others seeking to improve performance and physical appearance abuse them. These nonmedical uses are illegal and carry many health hazards. There are many signs that one can look for in a person who is suspected of using Anabolic Steroids. There is dramatic gain in weight and muscle mass over a short period of time (NIDA September1997). Another is severe acne. Others could be water retention, baldness or hair loss, even in the worst cases severe and sometimes violent mo...
"Anabolic steroids is the familiar name for synthetic substances related to the male sex hormones (e.g., testosterone). They promote the growth of skeletal muscle (anabolic effects) and the development of male sexual characteristics (androgenic effects) in both males and females”(National Institute on Drug Base).First, the benefits of steroids are very obvious to see. The user gains strength, mass, and speed in a short amount of time. Also, the user has a more aggressive attitude, which is good for football players. However, there are more bad side effects than good. The side effects include hair loss, acne, liver damage, kidney damage, increased breast tissue and becoming very aggressive. These are just some of the horrible bad side effects by using steroids.
Generally, steroid therapy, a non-surgical treatment, is only used to treat hemangiomas because their location may cause complications that must be treated immediately. For instance, hemangiomas appears in areas such as the head, neck, cheek, eyes, and nose; these are all locations which may cause blindness, airway blockage, or cardiac failure. According to the Vascular Birthmark Foundation, “Hemangiomas can grow for up to 18 months and then begin a long slow regression...
While the effects of steroids can seem desirable at first, there are serious side effects. Excessive use can cause a harmful imbalance in the body's normal hormonal balance and body chemistry. Heart attacks, water retention leading to high blood pressure and stroke, and liver and kidney tumors all are possible. Young people may develop and a halting of bone growth. Males may experience shrinking testicles, falling sperm counts, and enlarged prostates. Women frequently show signs of masculinity and may be at higher risk for certain types of and the possibility of birth defects in their children. The psychological effects of steroid use are also alarming: drastic mood swings, inability to sleep, and feelings of hostility. Steroids may also be psychologically addictive. Once started, users, particularly athletes, enjoy the physical "benefits" of increased size, strength, and endurance so much that they are reluctant to stop even when told about the risks. Major athletic competitions, including the Olympics, routinely screen athletes to prevent steroid use.
...d possibly sterility. Think of the body as an outlet, and the steroids are plugs. It is the steroids job to make sure that everything gets energy and runs smoothly. When working with the right amount of plugs, the steroids are usually successful. However, when extra plugs are forced to go into the same socket, the power can go out. The effect that the plugs were originally supposed to achieve are now backwards. Similarly, when steroids appear naturally in the body, they do their job well, but when foreign steroids are introduced into the body, destructive ends usually follow. We see from this example of steroid abuse that if normal function progresses to an extreme shape, healthy functioning becomes a disease.
The second layer of the skin is called the dermis and is also known as the middle layer. The dermis is what holds the body together. The dermis has layers to it as well as the epidermis. There are two layers to the dermis, the papillary layer and the reticular layer. The cells of the dermis are fibroblast, macrophages, mast cells, and scattered white blood cells (wbc’s). the dermis is richly supplied with nerve fibers and BV;s. dermal BV’s is also a part of the integumentary system, dermal BV,s have converging and diverging vessels that ar...
“Steroids are any type of a large group of fat-soluble organic compounds, as the sterols, bile acids, and sex hormones most of which have specific physiological action” (Dictionary.com). When our bodies are still developing, the effects of steroids can be dangerous and can also be permanent (“Above”). Steroids are made out of substances such as nandrolone, stanozolol, testosterone, fluoxymestrone, and oxandrolone. Sometimes people say when you can’t pronounce something, you probably shouldn’t use it. In the 1940’s testosterone began to be widely used in competitive sports, but the dangers of loading up on testosterone were not yet clear (“History”). Instead of using steroids for a bad reason, there is a medicinal purpose. Cortisteroids can treat arthritis, asthma, lupus and multiple sclerosis, eczema and rashes, and some types of cancer (“Steroids: Medline”). Also, steroids can be used to treat anemia, to improve weight loss due to severe illness, and to treat osteoporosis. Steroids can only be sold to you by a pharmacist f...
The epidermis, which is the outer layer of the skin, is made up of four to five layers in some parts (Shier, Butler, & Lewis, 2009). In the majority of the areas, just four layers can be differentiated: the stratum basale, stratum spinosum, stratum granulosum, and stratum corneum (p.119). Another layer is the stratum lucidum which can be found in the thicker part of the skin of the palms and ...
Steroids can have many health effects on your body. Many doctors say not to use steroids because of the possible long term effects. A source from a reputable website says, “It is speculated that possible long-term effects may include adverse cardiovascular ef...