Scar Ointment Theory

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A total of 90 patients (test [MEBO Scar ointment], n=40; control, n=50) were recruited in the study. All patients underwent elective surgery between February 01, 2013 and December 30, 2013.The majority of patients in the test group were female (n=30, 75%) with female to male ratio of 3:1; however, all participants in the control group were female. The mean age of the patients was 30 years (range: 10–60 years)(Table 1). There were no statistically significant differences between the test and control group with respect to type of surgery (Table 2)and type of incision (Table 3). Thyroidectomy was the most frequently performed surgery in the test group (30%), while breast mass excision biopsy was the most common in the control group. Revisional …show more content…

MEBO Scar ointment was found to producesignificantly better outcomes from the perspective of aestheticsin comparison to the control group. Overall, itching relief was observed in 97.5% patients; texture was normal in 50% and soft in 47.5%; scar shrinkage in 97.5%; skin color was close to normal in 75% and light in 22.5% (p<0.001, for all parameters) (Table 4). In this study ,there was no adverse effect or allergy were recorded in test …show more content…

It regulates the ratio between epithelial cells and collagen fibers as well as changes in their morphology. The imbalance of collagen metabolism and its arrangement is attributed to many factors which result in increased synthesis of collagen by fibroblasts and myofibroblasts, which in turn inhibit the activity of collagenase, leading to extensive scar hyperplasia. Matrix changes, mainly changes in fibronectin and mucopolysaccharides, result in scar stiffness. MEBO Scar Ointment can accelerate the re-arrangement of twisted collagen andreduce proliferation of fibroblasts, thus restricting scar hyperplasia. [11,13,14,15 ,21] The accumulation and synthesis of mucopolysaccharide can also be reduced once local tissues are compressed, thus reducing generation of collagen and the corresponding scar tissue. [11] Moreover, massaging the MEBO Scar ointment onto old scars can potentially reduce blood supply within scars, decrease synthesis of collagenous fiber, and,reduce α2-M (alpha 2-macroglobulin) globulin of collagenase in serum which facilitates collagenase activity and speeds up disintegration of collagen in old scars,this facility by applying MEBO scar ointment .

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