Lithium

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Lithium

Though the drug lithium is used for a number of disorders ranging

from acute depression to eating and personality disorders (Paykel,

1992), it's primary use is for bipolar disorder, also known as

manic depression. Patients with bipolar disorder "between two

poles: depression and its opposite, mania" (Kalat,2004), often

with periods of normal behavior in between (Jamison,1993). In

addition, the patient is also prone to "mixed episodes" in which

symptoms of both mania and depression are present. Intensity of

these episodes can range from mild to dangerous, as in the case of

a manic depressive mother who severed the arms of her 10 month old

daughter (Associated Press, 2005). Despite its genetic origin

(Kalat. 2004; Jamison, 1993; DBSA, 2005), the onset of symptoms

and behavior is rather late, averaging 18 years of age (Jamison,

1993).

There are two types of manic episodes: manic and hypomanic. The

DSM describes a manic episode as "a distinct period of abnormally

and persistently elevated, expansive, or irritable mood,"

(Jamison, 1993). Symptoms include inflated self esteem, a reduced

need for sleep, increased talkativeness and sociability, flight of

ideas, distractibility, an increase in goal directed activities

(such as work, school or sex), and an excessive involvement in

pleasurable activities (PsychologyNet, 2003). The occurrence of

these symptoms must not be able be confused with a mixed state

(see description below), must impair the individual's ability to

function normally, and cannot be explained by the effects of a

substance (i.e. alcohol, hallucinogenics) or a medical condition

(i.e. hyperthyroidism) in order for the episode to be considered

"manic....

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..." The Icarus Project. Retrieved February 28, 2005 from

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CONCLUSION

Lithium, or, more commonly, Lithium Salt, is an element used to

treat bipolar disorder in humans. Bipolar disorder consists of

severe highs and lows of mood, ranging from deep depression to

extreme mania. The cycling of the disorder depends on the person,

but it can vary from many shifts within one day (rapid cycling) to

extended periods of each. Lithium is indicated primarily for

patients who are not rapid cycling. Like many other medications,

the exact effects of Lithium are unknown. Psychiatrists and

Chemists have isolated many of the physiological and behavioral

changes that occur after the administration of Lithium, and yet

the exact cause of its therapeutic effect is not fully understood.

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