Samuel W. Melendy / William & Mildred Peters Summer Research Scholarship Proposal Name: Kerui Peng Advisor: Dr. Robert J. Straka Statement of Research Question: Hypothesis: There is a significant difference between the carrier status for prevalence of Human Leukocyte Antigen B*58:01 (HLA-B*58:01) allele between Minnesota Hmong and other Asian populations. We intend to genotype 239 Hmong and compare status of this genotype with that of Han Chinese and Korean cohorts to improve our understanding of the risk Hmong exhibit for this marker of severe cutaneous adverse reactions (SCAR) caused by allopurinol. Rationale: Severe cutaneous adverse reactions (SCAR) are types of cutaneous adverse reactions associated with considerable morbidity and …show more content…
The HLA-B*58:01 allele frequency for the Han Chinese cohort is reported to be 0.1964, and for the Korean cohort is reported to be 0.1224 with Caucasian carrier status at 0.0084. Minnesota Hmong are a unique sub-population of Asians at increased risk for gout/hyperuricemia6, for which allopurinol is first line therapy. Recognizing the Hmong a …show more content…
Melendy / William & Mildred Peters Summer Research Scholarship is stated in the following. With the announcement of the Precision Medicine Initiative (PMI) by president Obama on January 20, 2015, the concept of personalized medicine first came to my mind. I started to pay attention to precision medicine after that, actually, one of the most crucial factors which lead me to the University of Minnesota College of Pharmacy is that there has the unique institute of personalized medicine (PUMA-IPM). After the depth understanding of pharmacogenomics through the first-year’s pharmacy curriculum which taught by Dr. William Oetting and Dr. Pamala Jacobson, I am fascinated by this charming area in pharmacy. Pharmacogenomics is an area in which pharmacy expertise complements genomic information for drug selection and dosing. I seek to combine personalized medicine and individual care together with my pharmacy knowledge to treat patients and bring out the best therapeutic
Arch Dermatol. 2007;143(1):124–125. Puchenkova, S. G. (1996). "
What are the most important aspects of Hmong culture? What do the Hmong consider their most important duties and obligations? How did they affect the Hmong’s transition to the United States?
The Hmong people, an Asian ethnic group from the mountainous regions of China, Vietnam and Laos, greatly value their culture and traditions. The film “The Split Horn: Life of a Hmong Shaman in America” documents the seventeen year journey of the Hmong Shaman, Paja Thao and his family from the mountains of Laos to the heartland of America. This film shows the struggle of Paja Thao to maintain their 5000 year-old shamanic traditions as his children embrace the American culture. Moreover, the film shows that one of the major problems refugees like Paja Thao and his family face upon their arrival to the United States is conflict with the American medical system. Despite the dominant biomedical model of health, the film “The Split Horn” shows that
In the Great Planes of America there was a tribe of Indians known as the Arapaho Indians. There is little documentation as to when or where they came from but it is known they were in many different places in the Midwest including Oklahoma, Wyoming, Kansas and Colorado. The Arapaho Indians were nomadic people who survived on hunting buffalo and gathering. This tribe was greatly changed when they were introduced to horses. The horses provided them a new way to hunt battle and travel. The horse became the symbol and center of Arapaho nomadic life: people traded for them, raided for them, defined wealth in terms of them and made life easier.
Cobb, Torry Grantham, DHSc, MPH,M.H.S., P.A.-C. (2010). STRATEGIES FOR PROVIDING CULTURAL COMPETENT HEALTH CARE FOR HMONG AMERICANS. Journal of Cultural Diversity, 17(3), 79-83. Retrieved from http://search.proquest.com.ezp-01.lirn.net/docview/750318474?accountid=158556
American Indians have had health disparities as result of unmet needs and historical traumatic experiences that have lasted over 500 hundred years.1(p99) Since first contact American Indians have been exposed to infectious disease and death2(p19), more importantly, a legacy of genocide, legislated forcible removal, reservation, termination, allotment, and assimilation3. This catastrophic history had led to generational historical traumas and contributes to the worst health in the United States.2 American Indians and Alaska Natives (AI/AN) represent 0.9 percent of the United States population4(p3) or 1.9 million AI/AN of 566 federally recognized tribes/nations.5 American Indians/Alaska Natives have significantly higher mortality rates of intentional and unintentional injuries, chronic liver disease and cirrhosis, diabetes mellitus, cardiovascular disease and coronary heart disease and chronic lower respiratory disease than other American.6
After reading chapter 1, Birth, some of Hmong customs that stood out to me was when the parents had to bury the placenta after the child was born; depending on the gender the placenta was buries in a special place. I like the meaning that the placenta was a special garment that was first worn by the baby. Furthermore, another custom was when the mother had to satisfy any craving to prevent her baby from getting any type illness, and as well as having a special diet for the mothers after they give birth to help them cleans their body’s after the pregnancy. One custom that really stood out to me from the rest was “Lia’s hu plig” which was a party to appreciate a new child into the world and welcome the soul into a new body; they sacrificed chickens
Meurer, Michael. “Pharmacogenomics, Genetic Tests, and Patent-Based Incentives”, Boston University School of Law. Pages 1-8.
The ultimate goal of pharmacogenomics, as stated by Henig, “would be for everyone’s genome to be analyzed indi...
McBean, A. M., Li, S., Gilbertson, D. T., & Collins, A. J. (2004). Differences in diabetes prevalence, incidence, and mortality among the elderly of four racial/ethnic groups: whites, blacks, Hispanics, and Asians. Diabetes care, 27(10), 2317-2324.
Health, U.S. Department of Health and Human Services Office of Minority. "U.S. Census Bureau Report." 2007. OMH - Office of Minority Health. 3 December 2011 .
Having a wife is an important aspect in life because she is someone who you can have a physical, spiritual, and emotional bond and it’s when “two becomes one.” She’s your life partner, teammate and someone who should be there with you as you move through obstacles in life. Every culture and ethnicity have different views on what a wife should be and the Hmong wife (niam tsev) is certainly different. There are guidelines that show how a Hmong wife should behave. (See Figure) The Hmong wife is seen as someone who is responsible for all the home duties and basically cater to her husband. I believe that living in America, things are a bit different now. Whether it’s doing chores around the house, babysitting or cooking; both should be responsible for these duties. Just
Mandeep Bajaj, M. (2013, January 24). Diabetes in Asian Indians in the United States. Retrieved December 9, 2015, from indoamerican-news.com: http://www.indoamerican-news.com/?p=14157
Studies suggest that Indigenous peoples in Canada experience a disproportionate burden of HCV in comparison to the general population. For example, the A-track pilot study found a self-reported lifetime HCV seropositivity of 46.1% among a cohort of Indigenous peoples in Regina [13]. Similarly, a 2010 summary of data from three national surveillance systems in Canada reported that the rate of HCV was almost five times higher among Indigenous peoples compared to the non-Indigenous population [5]. These results were further echoed in a 1999-2004 study in six health regions in British Columbia, Alberta, Manitoba, Ontario and New Brunswick, where 15.2% of the incident cases of HCV
There is not an ethnic group that is not affected by heart disease. However, “the cardiovascular disease death rate among African Americans is 34 percent higher than for the overall U.S. population”. (“The Facts of Cardiovascular Disease”) African American women ages 50 and up are twice as likely as Caucasian women to be diagnosed with heart disease, and is more likely than Caucasian women to have a heart attack. A heart attack is the most common outcome of heart disease.