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Acute renal failure pathogenesis
Patho acute renal failure
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Acute Renal Failure
Explain the pathophysiology of acute renal failure. Include prerenal, intrarenal and postrenal causes.
Kidneys are a vital part of our bodies. Their main function is to remove waste from our body. They also release three important hormones:
• Erythropoietin – Stimulates bone marrow to create more red blood cells.
• Renin – Is responsible for regulating blood pressure.
• Calcitrol – Helps to maintain the calcium in our bones.
During acute renal failure or (ARF) the kidneys suddenly stop working which in turn sets off a chain reaction in our bodies and can lead to death. There are three different types of ARF.
1. Prerenal is the most common form of ARF. It is when there is a sudden drop of blood flow to the kidneys. This occurs most often in an accident when there is injury to the kidneys or a form of severe illness.
2. Intrarenal is caused by inflammation, drugs such as antibiotics and infections, for example, glomerulonephritis, which is caused by the strep bacteria.
3. Postrenal is the least common form of ARF. This occurs when there is a sudden obstruction of urine flow that can result from a kidney stone, enlarged prostate, injury or a bladder tumor.
What diagnostic exams would be used to diagnose acute renal failure?
How do these tests change as renal failure progresses through its three stages? Discuss, compare and contrast the three stages.
To diagnose acute renal failure, you will monitor kidney function using both blood, urine and imaging tests.
• The blood tests that are used are Bun and Creatinine. These two tests monitor the amount of urea and creatinine in the blood. Urea is a byproduct of protein breakdown and creatinine is a byproduct of muscle...
... middle of paper ...
... the patient goes on to have a happy, healthy life
with no renal complications.
References
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"Kidney Diseases." Tests Used to Diagnose Kidney Disease. N.p., n.d. Web. 4 Dec. 2013. .
"Read What Your Physician is Reading on Medscape." eMedicineHealth. N.p., n.d. Web. 4 Dec. 2013. .
http://www.bing.com/search?q=ncbi.nlm.nih.gov.kidneydisease&qs=n&form=QBRE&pq=ncbi.nlm.nih.gov.kidneydisease&sc=0-0&sp=-1&sk=&cvid=f1a55823ae024f59a827e21c42da91ae
Dharmajan,T.S.,Yoo.012,Renal Insufficiency, Chronic-In Old Age Journal of the American Medical Directors Association
Health Communities,2011, Pre Renal, ARF Overview, Causes-Acute Renal Failure.
The New England Journal of Medicine -- February 1, 1996 -- Vol. 334, No. 5
There are two types of glomerulonephritis—acute renal failure (ARF) and chronic kidney disease (CKD). The ACF form generally develops suddenly as a result of an infection or illness, such as, group A streptococci bacteria, hepatitis, or in diseases such as lupus or HIV (Mathias, 2013). This type may require dialysis to replace renal function while it lasts, however, kidney function usually returns after the primary illness is treated. Many acute patients will not have any other complications as no permanent damage is done. Whereas CKD is found in a person that has had glomerulonephritis for months to years in some cases and may be asymptomatic until the kidney has become irreversibly damaged. ARF can evolve to become chronic if the glomeruli do not respond to
The chemistry test shows the levels of electrolytes found in the blood: sodium, potassium, chloride, phosphorus, magnesium and calcium. Imbalances in these electrolytes can cause complications, which especially in the case of potassium, can be deadly. Also shown by the chemistry test, blood urea nitrogen and creatinine levels can show how well the patient’s kidneys are functioning in filtering waste from the blood. Trauma and blood loss can affect how the kidney’s function not only in filtering waste, but also in acid-base balance, and balancing electrolyte levels. Another marker of kidney function is the glomerular filtration rate, which measures the rate filtrate is created by the glomerulus of the kidney (Winkelman, 2016). This is controlled by the kidneys themselves, meaning changes in the function of the kidneys can lead to an altered filtration rate (Winkelman, 2016). Lactic acid is measured by the chemistry test also, and an increase in lactic acid can signify acidosis caused by the lactic acid being formed by cells that do not have adequate oxygen to process glucose for energy (Workman, 2016). This decrease in available oxygen could be caused by damage to or impairment of the lungs. Carbon-dioxide, which is also measured by the chemistry test, can show
ED. Mayo Clinic Staff -. Mayo Foundation for Medical Education and Research, 05 Jan 2012. Web. The Web.
The renal disease are common nowadays .The acute renal failure is a medical term means that the kidneys stopped from working and not able to clear toxins from body ,not able to maintained a stable electrolyte balance inside the body and not able to secret the extra fluid as urine outside the body. The renal replacement therapy (RRT) or dialysis has been discovered on 1913 by Able, Rowntree and Turner in London, UK.
Bowers, L., Allan, T., Simpson, A., Nijman, H., & Warren, J. (2007). Adverse Incidents, Patient
United States Renal Data System (USRDS). (2008). Annual data report: Incidence and prevalence. Retrieved July 8, 2009, from http://www.usrds.org/2008/pdf/V2-02-2008.pdf
Healthy kidneys clean the blood by filtering out extra water and wastes. They also make hormones that keep your bones strong and blood healthy. When both of your kidneys fail, your body holds fluid. Your blood pressure rises. Harmful wastes build up in your body. Your body doesn't make enough red blood cells. When this happens, you need treatment to replace the work of your failed kidneys.
... Medicine. 3rd ed. Vol.3. Detroit: Gale, 2006.2139-2141. Gale Virtual Reference Library. Web. 3 Apr. 2014.
Turner, B. J., Newschaffer, C. J., Zhang, D., Fanning, T., & Hauck, W. W. (1999). Translating clinical trial results into practice. Annals of Internal Medicine, 130(12), 979-986.
As mentioned above; Hypoalbuminaemia is a predominantly events that occur due to losses of protein urinary. In response to this, hepatic albumin synthesis increased but they are still insufficient to prevent the fall in the serum albumin concentration. Proteinuria, Nephrotic range proteinuria is almost invariably due to glomerular disease.
All play a role in removing waste from your body. Your kidneys filter waste from your blood and regulate the concentrations of many substances. Tubes called ureters carry urine from your kidneys to the bladder, where it’s store until it exits your body through the urethra.
Kidney Function Introduction and definition of terms: The kidneys are the main organs in the urinary system. They filter waste products out of blood from the renal artery. These are then excreted. Useful solutes are reabsorbed into the blood. They also have a major homeostatic role in the body, and help to control the water content (osmoregulation) and pH of the blood.
Kidney plays an important role in the smooth mechanism of different functions in our body. Failure of Kidneys can be a great threat to the life of a person. Since the lifestyle of people today has changed to a great extent, people often complain in pain in kidney, stone formation, intestinal disorders, etc… Failure of kidneys is a threat to life. Since infection in one kidney affects the other one drastically, it becomes essential for the person to cure it on urgent basis. Dialysis is a very common treatment that is often taken by kidney patients. Since dialysis is a very painful process, there are times when patients are unable to stand it as well.
"MedlinePlus - Health Information from the National Library of Medicine." National Library of Medicine - National Institutes of Health. Web. 06 Mar. 2011.