Continuous Renal Replacement Therapy in the Intensive Care Unit

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The renal disease are common nowadays .The acute renal failure is a medical term means that the kidneys stopped from working and not able to clear toxins from body ,not able to maintained a stable electrolyte balance inside the body and not able to secret the extra fluid as urine outside the body. The renal replacement therapy (RRT) or dialysis has been discovered on 1913 by Able, Rowntree and Turner in London, UK. In medicine dialysis is primarily used to provide an artificial support for the lost kidney function in people with renal failure. Currently there are two types of renal replacement therapy. The original dialysis which we called it hemodialysis used for patients with chronic renal failure, needs the patients to come to hospital 2-3 times per week. This type of dialysis called the intermittent hemodialysis .However the intermittent hemodialysis is difficult to do it in the intensive care population with acute renal failure because of the hemodynamic instability and those type of patients usually are the most sick and critically ill patients within the intensive care units and have multiorgan dysfunctions, so medically is too difficult to do for them intermittent hemodialysis. In addition intermittent hemodialysis will increase the mortality and morbidity among them. Within the modern intensive care units new way of dialysis has been developed 30 years ago called continuous renal replacement therapy (CRRT).The definition of (CRRT) is any extracorporeal blood purification therapy intended to substitute for impaired renal function over an extended period of time and applied for or aimed at being applied for 24 hours/day, Bellomo R., Ronco., Mehata R. The CRRT was found because the traditional way of ... ... middle of paper ... ...ed trail .Lancet 356(9223), 26-36 (2)Saudan,P.,Niederberger,M.,De Seigneux,S.,Romand,J.,Pugin,J.,Pernrger,T.,& Martin,P.Y(2006).Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure .Kidney international,70(7),1312-1317. (3)Bellomo,R.,Cass,A.,Cole,L.,Finer,S.,Gallagher,M.,Lo,S.,McAthur,C.,McGuinness,S.,Myburgham J.,Norton,R.,Scheinkestel,C.,& Su,S. for renal study investigators(2009).Intensity of continuous renal-replacement therapy in critically ill patients. The New England Journal of Medicine, 361(17), 1627-1638. (4)Bellomo,R., Ronco ,C.,Mehata ,R.Nomenclature for continuous renal replacement therapies,AJKD,VOL 28,NO.5,Suppl 3,November 1996 (5)Tolwani AJ,Gampbell RC,Stofan BS,Lai KR,Oster RA,Wille KM.Standard versus high dose CVVHDF for ICU-related acute renal failure.J Am soc Nephrol 2008;19:1233-8

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