What is hepatic cirrhosis? According to the medical dictionary hepatic cirrhosis is when scar tissue replaces the liver’s healthy tissue. This disease changes the structure of the liver and blood vessels that nurture it. It reduces the liver’s capability to produce proteins and process hormones, nutrients, medications, and poisons. Cirrhosis is an illness that gets worse over time and possibly can become life threatening. This serious illness is ranked as the ninth leading cause of death in the U
DEFINITION (1) Cirrhosis can be simply defined as diffuse fibrosis associated with parenchymal nodules. It involves the whole liver rather than a small part even though on occasion the fibrosis may be more severe in one or other lobe. Fibrosis results partially from collapse of the new fibre formation and is usually regarded as a consequence of liver-cell necrosis. The nodules of a cirrhotic liver are the surviving parenchyma. But they are strutually altered. They vary greatly in size and appearance
liver is not able to function properly and starts to deteriorate this is known as a condition called Cirrhosis. The healthy liver tissue is replaced with scar tissue and the blood flow throughout the liver becomes blocked. When the healthy tissue is replaced with scar tissue, the liver will shrink. The liver can repair itself and function properly if the Cirrhosis is mild, but if the Cirrhosis slowly develops over the years, the liver
married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the liver that interferes with its
Serum biomarkers Many serum biomarkers and biomarker panels have been studied for the assessment of fibrosis and diagnosis of cirrhosis. Overall, these markers are good indicators of the presence or absence of fibrosis (F0 or F>0), or the presence of cirrhosis (F4 or F<4). However, their use in distinguishing between fibrosis stages, or the rate of fibrosis progression has not been well established. Similarly, the prognostic value of many serum biomarkers has not been studied. These biomarkers can
that would be needed to save his life. He was placed in the Intensive Care Unit (ICU) and remained under sedation until he was extubated and transferred to the post-critical floor. It is postulated that JR’s history of alcoholic hepatic failure, cirrhosis, and end-stage liver disease could have lead to high circulating ammonia levels. High ammonia levels then could have lead to JR to become unresponsive, although the actual proven cause was never noted. Another theory could have been the use of illegal
Cirrhosis: An Analysis of Evidence-Based Practice Characterized by progressive tissue injury and scarring, cirrhosis is among the leading causes of chronic liver failure in the United States. Recent research conducted by the National Institutes of Health indicated that the prevalence of cirrhosis, especially in clients diagnosed with Hepatitis C, has increased steadily throughout the past decade and will likely continue to increase in the future (Kanwal et al., 2011). Caused by recurrent tissue damage
into cirrhosis if not treated in time. For example fatty liver is disease that can develop into hepatitis or cirrhosis. This disease is most commonly developed by through acute alcohol abuse or substance abuse. This disease can be reversible with absence before developing into cirrhosis, but 20% of heavy users will fail to stay absent and develop cirrhosis. A second disease you might develop before getting to cirrhosis is hepatitis A, B, or C an infection of the liver can develop into cirrhosis. These
Importance of the Topic Cirrhosis is a disease in the liver. The liver is scarred and the scar forms due to either injuries or chronic diseases. The liver tissues, in general, are vital part of the body since it makes protein, cleans the blood, stores energy, fights infection and helps digest food. If the liver tissue is scarred, it cannot function the way it should be. If this occurs, cirrhosis can lead to symptoms such as: high blood pressure specifically in the vein where the liver entrance is
“Ascites is the most common major complication of cirrhosis and is associated with a poor quality of life, increased risks of infections, renal failure and a poor long-term outcome.”7 Ascites is primarily triggered by vasodilatation of the splanchnic arteries. Portal hypertension initiates the release of