Smallpox: Different Types and their Symptoms
Smallpox as a devastating disease for thousands of years – it killed 300 million people just during the 20th century. There are two forms of the virus: Variola major (the deadlier) and Variola minor. Richard Preston in The Demon in the Freezer describes its effects on the body saying, “The virus had stripped the skin off the body, both inside and out, and the pain… seemed almost beyond the capacity of human nature to endure” (Sherman, pg 197). The two strains of smallpox discussed in this paper give insight to the symptoms of the now eradicated smallpox. Fulminating smallpox was insanely hard to detect, because the patient usually died before symptoms of smallpox could even appear. Malignant confluent smallpox had a much longer course of infection – it could last for a little over two weeks before claiming the patient’s life. Although these two forms were rare, every type of smallpox (if survived) would leave disfiguring scars on the face, known as pockmarks. Edward Jenner used the fact that milkmaids had fair complexions free from pockmarks to his advantage, and came up with his famed vaccine. Overall, much can be learned from smallpox, the only major human disease to have been eradicated.
A scourge that could topple entire empires within weeks, an enemy that was blind to race, gender, age, or class, smallpox left its mark on those that were able to survive. Smallpox, or the variola virus could easily wipe out entire cities (Irwin W. Sherman, pg 191-192) and was a plague that was nearly impossible to cure, yet it is now the only virus that has been successfully eradicated- the World Health Organization proclaimed it to be eradicated in 1979 (World Health Organization, pa...
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...it plagued mankind for 3,000 years (Sherman, pg 204). It changed human history while it thrived, as it did with its death. Smallpox is proof that medicine has the power to rid the world of the many diseases that plague the world today.
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“Future nations will know by history only that the loathsome smallpox has existed and by you extirpated”. This quote comes from Thomas Jefferson to Edward Jenner, he founder of the smallpox vaccine. It would only be 100 years later that Jefferson would see his dream fulfilled, but not without struggle. In House on Fire, author William H. Foege shares his first hand view of the lengths that society needed to go through to rid the world of the disease that had plagued it for so long. The story of the fight against smallpox extends long before our efforts for global eradication and is a representation of how society deals with widespread disease. House on
The Demon in the Freezer by Richard Preston is an intriguing book that discusses the anthrax terrorist attacks after 9/11 and how smallpox might become a future bioterrorist threat to the world. The book provides a brief history of the smallpox disease including details of an outbreak in Germany in 1970. The disease was eradicated in 1979 due to the World Health Organization’s aggressive vaccine program. After the virus was no longer a treat the World Health Organization discontinued recommending the smallpox vaccination. In conjunction, inventory of the vaccine was decreased to save money. The virus was locked up in two labs, one in the United States and one in Russia. However, some feel the smallpox virus exists elsewhere. Dr. Peter Jahrling and a team of scientists at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland became concerned terrorists had access to the smallpox virus and planed to alter the strain to become more resistant. These doctors conducted smallpox experiments to discover more effective vaccines in case the virus were released. Preparedness for a major epidemic is discussed as well as the ease with which smallpox can be bioengineered.
First of all the setting affects the plot because of how the disease would spread very fast. It can move very fast because before it was eradicated there were so many deaths. The text states, “Prior to vaccination, 400,000 smallpox deaths occurred in a routine year in Europe” (Cooney 92). This shows how just in one year 400,000 people died from smallpox. On page 92 the author writes, “But only one-third of smallpox patients died, so the actual number getting smallpox was 1.2 million” (Cooney). This shows that it was moving so fast in Europe that 1.2 million got infected by smallpox. With all of the things discussed in the paragraph the setting affected the plot because of the smallpox virus
In closing, the variola virus affected a great amount in that era including, military strategy, trade, and native populations. Elizabeth A. Fenn’s book Pox Americana: The Great Smallpox Epidemic of 1775-82 sheds light on a significant aspect of that era that had not been given proper credence beforehand. She also illuminated the effect of smallpox when it came to race and social status. With regard to race, smallpox decimated much of the non European populations partly because of their lack of an innate immunity to that virus and Europeans lack of regard for those of a different race. Fenn’s argument on social status showed how the poorer strata’s of society suffered more severely from the variola virus because of their lack of finances to get inoculated; thus, the poor often suffered a worse strain of the virus which often lead to death.
A different perspective on a smallpox epidemic during the French and Indian War appears in Andrew J. Blackbird's History of the Ottawa and Chippewa Indians of Michigan. Blackbird, Chief Mack-e-te-be-nessy, was a member of a distinguished Ottawa family from the northwest shore of the Michigan lower peninsula. He wrote his History late in life, after a long career in education, politics, and public service.
One similarity between smallpox and the black death was that they both established new trade with countries they had rarely traded with before. With smallpox, the Americas were faced with a labour shortage due to the amount of people smallpox had killed. The labour was needed to work in silver mines and sugar plantations.To fill the shortage of labour, slaves were traded from the Guinea Coast, somewhere there was not much trade in before, but now was a bustling center of trade due to the demand for slaves. Similarly, during the black death, there was a shortage of people because of the shrunken population. There were less people buying wool, wine, and cheese, so merchants from Europe sook out customers in different areas. Some such areas were
The perspective the author gives to this book is a unique. Smallpox according to most histories does not play the role of a major character, but a minor part. In my opinion smallpox was a major factor during the Revolutionary War, and Feen focuses on several key areas which allows us to see just how bad this epidemic was and the grip it had not only on the soldiers, but the colonist as well.
Eradication is the concept that a disease is entirely eliminated in a region. (Carter n.d.) Only one infectious disease to date, smallpox, has been categorized as eradicated worldwide (CDC 2010). How did this eradication occur? From 1958 to 1965 all fifty states enacted legislation to mandate school age children receive the small pox vaccine (College of Philadelphia). Consequently, by 1971, no small pox cases had been reported in the United States for 20 years. The last known smallpox case in the world was in Somalia in 1977 (CDC 2010). Even though small pox is the only listed eradicated disease, the Carter Foundation has listed six other diseases as having the potential to be eradicated: lymphatic filariasis (Elephantiasis), polio, measles, mumps, rubella, and pork tapeworm. In addition to these previous listed diseases are to date the following diseases which are considered preventable by vaccination: chicken pox, diphtheria, Haemohphilus Influenza type B, Hepatitis A and B, HPV, Influenza, Measles, Meningococcal Disease, Mumps, Pertusis, Pneumonia, Polio, Rotavirus, Rubella, Shingles, Smallpox, Tetanus, Yellow Fever, and STDs (Carter n.d.).
In order to understand the history of smallpox one first has to understand how diseases like it evolve. Much like other species, diseases that survive in the long run are the microbes that most effectively reproduce and are able to find suitable places to live. For a microbe to effectively reproduce, it must "be defined mathematically as the number of new infected per each original patient." This number will largely depend on how long each victim is able to spread the virus to other victims (Diamond, 198).
From 166 A.D. to 180 A.D., The Antonine Plague spread around Europe devastating many countries. This epidemic killed thousands per day and is also known as the modern-day name Smallpox. It is known as one of deadliest plagues around the world.
The American Revolution was started in 18th century based on the political, social and economical reasons in the thirteen colonies. The colonists discovered the United States of America by refusing the nobility and monarchy of the Great Britain. During the Revolution, an epidemic disease called smallpox was spread devastatingly and frequently. Smallpox was an enormously contagious disease caused by a specific type of virus variola which spread into the thirteen American colonies. The disease was new in the country to take place in Boston, Massachussetts first and by spreading the virus made a severe threat all over. It began with infection mainly in the blood vessels of the human skin and mouth, resulted in different kinds of symptoms for
Although the Columbian Exchange allowed for the beneficial exchange of cultures, ideas, foods, and animals around the world during the 1450-1750 time period, it also had a dark side. One detrimental result of the Columbian Exchange would be the spreading of smallpox from Europe to the New World.
diseases in the world, and it was declared eradicated in 1980 (Smallpox). This and all the other
During one of his earlier apprenticeships, Jenner noticed milkmaids with a disease called cowpox. Cowpox is a close relative to smallpox and is only mild in humans. Pustules appear on the hands and a basic cold is also brought on. At Jenner’s young age he was able to link these two viruses together and come up with a theory for immunization. In 1796, while still attending medical school, Jenner decided to test this theory between smallpox and cowpox. He used a dairymaid, who was a patient of his named Sarah Nelms, who had contracted cowpox and had ripe pustules on her hands. Jenner realized this was his opportunity to test someone who had not contracted smallpox yet. He picked an eight-year old boy named James Phipps to use as his test subject. He scraped open a spot of James' arm and rubbed in a dissected piece of Sarah Nelms pustule into the open wound. A couple days later James became ill with cowpox but was well again within a week. This test proved that cowpox could be spread between humans as well as cows. Jenner's next test would be if the cowpox virus gave James immunity against smallpox. On July 1st of 1796, Edward Jenner obtained an infected smallpox pustule and scratched the virus filled pus into James' arm. This technique of placing a virus into a patient is called variolation. James Phipps did not develop smallpox within the