Normal Anatomy and Physiology Blood is one of the components that make up the circulatory system in the human body. It transports oxygens and nutrients to and removes waste materials from other systems of the body. Blood has different components which predominantly consist of red blood cells (RBC) also known as erythrocytes. RBCs have a lifespan of 120 days and depending on the age and gender of the healthy individual ranges between “4,200,000 to 6,100,000/mm3” (Ignatavicius & workman, p. 857). When matured, RBCs have a non-nucleated biconcave disk shape and a flexible membrane that allows for easy transport through capillaries to most of the peripheral blood tissue. They are also defragmented into iron and amino acids in the spleen; the iron is reabsorbed into the bone marrow and assimilated for storage in the …show more content…
The RBCs of a patient with sickle cell disease has 40% abnormal beta hemoglobin chains which form the hemoglobin S (HbS), inherited from one or both parents, thus possessing two of these alleles and a total hemoglobin of 80-100%. A carrier of this genetic disorder would have one HbS and HbA allele. In decreased oxygen conditions, the RBCs of the SCD individual resemble a sickle or half-moon shape which causes it to stick together thereby blocking blood flow in the vessels causing pain in the affected joints. This is known as a “vaso-occlusive event (VOE)” (p. 870) and it results in increased heart rate, reduced pulse, low blood pressure and decreased capillary refill. VOE also leads to reduced oxygen capacity of the hemoglobin reaching the tissue and other parts of the body leading to ischemia. In severe cases and with repeated ischemia, the organs of the body such as spleen, liver, heart, kidney, brain, joints, bones, and retina gradually decline in activity and function. (Ignatavicius & Workman,
In this paper I will clarify the relation between the integumentary system and the skeletal system. During this paper I will address how the two systems work together to maintain homeostasis and what occurs when balance is not maintained between the integumentary and skeletal system. During this paper I will explain how osteoporosis is directly linked between both the integumentary and skeletal system and ways to prevent or yield this disease.
Red blood cells deliver the oxygen to the muscles and organs of the body.
According to Virtual Medical Centre (2014) the primary function of the blood is to act as a transport, to give the body protection and to help regulate. The blood dissolves gases such as oxygen and carbon dioxide. The blood also transports vital nutrients throughout the body, such as micro-nutrients, fatty acids and amino acids. The flow of the blood helps to regulate the body’s temperature. Also the blood removes wastes material of metabolism. Blood cells (white and red cells) are carried through the body to help with the body’s natural defense, blood clotting and the carry anti-bodies.
Sickle cell anemia is a disease that reforms the patient’s red blood cells, which makes the red blood cells has an abnormal shape like a sickle. Sickled red blood cells can result to severe anemia; decrease causes numerous painful symptoms in patients. A defective protein called hemoglobin is what cause the abnormal shape of the red blood cells in the sickle cell patients.
Sickle-cell anemia is a genetic disorder that makes your body produce red blood cells that are abnormal in shape. This disease is also widely known as hemoglobin SS disease. Unlike normal red blood cells, sickle cells are rigid and tenacious. Due to their shape and rigidness, they can block blood flow. In turn, this could cause organ damage to the body. Sickle cells are also fragile and die very easily due to the fact sickle cells have a lifespan of twenty days instead of the normal one hundred and twenty days for normal red blood cells.This causes the body to have a lower blood cell count, hence the name anemia in sickle cell anemia.
Sickle cell anemia occurs when an abnormal form of hemoglobin (HbS) is produced. HbS molecules tend to clump together, making red blood cells sticky, stiff, and more fragile, and causing them to form into a curved, sickle shape. Red blood cells containing HbS can go back and forth between being shaped normally and being sickle shaped until they eventually become sickle shaped permanently. Instead of moving through the bloodstream easily, these sickle cells can clog blood vessels and deprive the body's tissues and organs of the oxygen they need to stay healthy.
The problem is that when a red blood cell with hemoglobin S releases oxygen, the cell changes from the usual doughnut shape to a sickle or S shape, and becomes stiff rather than soft and flexible like normal red blood cells. This "sickled cell," which resembles a crescent moon, can't continue to glide through the small blood vessels as usual. Instead, it gets stuck in the tiny blood vessels, blocking the flow of blood and causing pain.
Sickle cell anemia is a blood disorder that is inherited from both parents in which the body produces abnormally shaped red blood cells. In sickle cell anemia, the hemoglobin in red blood cells links together; resulting in the red blood cells to become rigid and a C-shaped. These deformed cells block blood and oxygen flow in blood vessels. Sickle cells deteriorate quicker than normal red blood cells, which results in anemia.
A patient with sickle cell has inherited the condition from both parents, and it all starts in the hemoglobin. Hemoglobin is “an iron-containing protein in red blood cells that reversibly binds to oxygen” (Reece, Urry, Cain, Wasserman, Minorsky, & Jackson, 2011). Obviously, hemoglobin is an important substance for oxygen to be transported in red blood cells. However, a patient with sickle cell has irregular hemoglobin cause by inherited genes. This “oxygen delivery” system cannot function properly because a gene
The Circulatory System is a transportation and cooling system for the body. The Red Blood Cells act like billions of little mail men carrying all kinds of things that are needed by the cells, also RBC's carry oxygen and nutrients to the cells. All cells in the body require oxygen to remain alive. Also there is another kind of cells called white blood cells moving in the system. Why blood cells protect from bacteria and other things that are harmful. The Circulatory system contains vein arteries, veins are used to carry blood to the heart and arteries to carry the blood away. The blood inside veins is where most of the oxygen and nutrients are and is called deoxygenated and the color of the blood is dark red. However, blood in the arteries are also full of oxygen but is a bright red. The main components of the circulatory system are the heart, blood, and blood vessels.
In this experiment, we determined the isotonic and hemolytic molar concentrations of non-penetrating moles for sheep red blood cells and measured the absorbance levels from each concentration. The results concluded that as the concentration increased the absorbance reading increased as well. A higher absorbance signifies higher amounts of intact RBCs. The isotonic molar concentration for NaCl and glucose is 0.3 M. The hemolysis molar concentration for NaCl and glucose is 0.05 M. Adding red blood cells to an isotonic solution, there will be no isotonic pressure and no net movement. The isotonic solution leaves the red blood cells intact. RBC contain hemoglobin which absorbs light, hemoglobin falls to the bottom of the tube and no light is absorbed. Determining the isotonic concentration of NaCl and glucose by finding the lowest molar concentration. In contrast to isotonic molar concentration, hemolysis can be determined by finding the
Red blood cells are carriers of oxygen. A percentage of these cells contain hemoglobin, which has the capacity to combine with iron. It's the iron-hemoglobin molecular structure that helps carry oxygen-rich blood from the lungs to your tissues and in return, delivers carbon dioxide back to the lungs to be expelled. A CBC with Differential that shows low red blood cell levels can indicate anemia. RBCs comprise about 40% of total blood volume; the RBC count is the number of red blood cells per cubic millimeter of blood (Rauen, 2012). Normal red blood cells values vary a...
The history of anatomy and physiology dates back to ancient Egyptian times when humans were mummified after death and bodies would be stripped of their internal organs during the embalming process. It was not until much later when Hippocrates II, known as the father of medicine, was the first to write about human anatomy. Shortly after that, the Alexandrian Medical School was established, where human dissection was allowed for the first time, which promoted research and new discoveries in the field. From there, many other influential researchers came up with theories regarding the cardiovascular and nervous systems, etc; however, the missing links in some of the earlier theories was found with the discovery of the microscope, which changed the focus of research and led to many advancements in the field.
Red Blood Cells contain hemoglobin molecules to help bind to oxygen to bring to other tissues. Without this function, cells would not be able to go through the process of cellular respiration and can only survive a short time. Red Blood Cells are also able to carry bicarbonate as a waste product and carry a variety of hormones to communicate between organs.
The human body is very complex. It is like a job. You have to do a million things in one day to make it through the day. The body uses nine systems to do all of those jobs. They all have separate functions, but some work together. Each system is also made up of organs. There are many ways to care and protect the systems from the many different problems they can have. There are also many interesting facts about each system.