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Literature review for antibiotics
Review literature on discoveries of antibiotics
The challenge of antibiotic resistance
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Bacterial Resistance
Bacterial resistance is a problem that has profoundly impacted the medical community. Bacterial resistance results when bacteria become resistant to individual antibiotics through the development of specific defense mechanisms which render the antibiotic ineffective. This problem has become evident in recent years as numerous cases have been reported in which antibiotics are not effective against the bacteria that they have fought off for years. The recent troubles with bacterial resistance have caused panic throughout the United States. The pharmaceutical industry hasn’t been producing many antibiotics because they thought that the antibiotics they had created had solved many of the problems resulting from bacterial infections. An increasing amount of attention has been given to antibiotic resistance with each passing year and experts are optimistic for the future; however, the threat of bacterial resistance exists today and is a major cause for concern.
The discovery of penicillin the 1940s proved to be the dawn of the antibiotic era. In less than two decades, major advancements had been made in the development of antibiotics. There were so many different antibiotics developed that doctors and scientists focused their attention on other problems plaguing the nation. Doctors prescribed antibiotics frequently, often when they were not even needed. According to a 1998 report by the Institute of...
Bacterial growth is defined as the division of one bacterium, resulting in two identical cells. This process is referred to as the binary fission that doubles the bacteria population. All three cells are identical. The bacteria go through a growth spurt in order for it to survive and grow. In order to show a bacteria growth curve, scientists create a perfect habitat to predict the bacteria’s growth curve. The growth curve gives the scientists an idea of how certain bacteria will act and how
Introduction Bacterial vaginosis is known to be the most common cause of abnormal vaginal discharge in women of childbearing age (Hay, 2010). Bacterial vaginosis is the result of the substitution of normal vaginal lactobacilli with anaerobic bacteria Gardnerella vaginalis and Prevotella, Peptostreptococcus and Bacteroides spp., which will result loss of the normal vaginal acidity (Turovskiy, Sutyak Noll, & Chikindas, 2010). Bacterial vaginosis is the main trigger of vaginal discharge or malodor in
beneficial to both mother and baby and the environment as well. Breastfed children are less likely to have ear infections, allergies, vomiting, pneumonia, urinary tract infections, chronic digestive disease, insulin-dependent diabetes mellitus, bacterial meningitis, research also indicates that breastfeeding may help protect against Sudden Infant Death Syndrome (SIDS), women who were breastfed as infants have a lower rate of breast cancer, and breastfeeding helps promote bonding between mother and
Investigating the Optimum pH Bacterial and Mammalian Amylase Digests Starch Solution [IMAGE] Biology Coursework Monique Noel 12T Finding the Optimum pH Bacterial and Mammalian Amylase Digests Starch Solution. Introduction I am investigating the optimum pH bacterial and mammalian amylase digests starch solution. To do this I will conduct an experiment using bacterial and mammalian amylase, subjecting them to varying pH levels and record at which pH level the enzyme
Gardnerella vaginalis started a controversy due to different interpretations of its clinical significance, taxonomic position, and Gram stain reaction. The organism was first named Haemophilus vaginalis. However, it lacked some of the characteristics the Haemophilus species required. It was then referred to as Corynebacterium vaginale. It was later changed to Gardnerella vaginalis when a new genus was necessary (Catlin, 1992). This paper will focus on the characteristics of G. vaginalis and how it
Microbial pigments have antioxidant activity because of their biological functions.and these pigments are Carotenoid ,naphthaquinone,and Violacein. Bacterial pigment plays role as antioxidant by inhibiting photodynamic lipid peroxidation in liposome and give protection against photodamage (Rajagopal et al. 1997).Xanthomonadin is example of this bacterial pigment. Yellow pigment from Staphylococcus aureus which is called as staphyloxanthin.it prevents CCl4 induced oxidative stress in swissalbino
typically when you’re sick, you go to the doctors. If your doctor happens to suspect that you may have an infection, he or she may order to have a culture, and/or a gram stain done to check for bacteria. If it happens to be that you do have a bacterial infection, your doctor can then have a gram stain done on the bacteria to see if the bacteria in your infection are gram negative or gram positive bacteria. A gram stain can be performed on various types
After gram staining, it was revealed that unknown 1 microscopic morphology was Gram positive cocci in clusters Staphylococcus epidermiclis. When observed under the microscope, the bacteria’s morphology displayed a purple color, round shape, and clustered together like bundles of grapes. It was difficult to locate the specimen due to the student’s lack of experience with using the microscope. The student forgot to use the stage clip to hold the slide in place, which made it difficult to control
fight against bacterial infections, however their effectiveness has waned in recent times due to the advent of antibiotic resistant strains of bacteria. According to a review by P, the uses of antibiotics, as well as influences from the environment have allowed such bacterial strains to respond to changes in their environment rapidly, and so develop resistance. This acquired ability can have serious and broad implications in the medical field, evident in a study by O into the resistance of intestinal
The Necessity to Prevent Antibiotic Resistance Approximately one year ago in Kentucky, a man went to sleep thinking he might have caught a flu. The next day, he is rushed to the local hospital while coughing up chunks of lung tissue; within a few hours he experiences organ failure and lips into a coma. Over the next two days, two other patients come in with the same symptoms and die almost immediately. This epidemic that swept over this small area in Kentucky was an ultra resistant strain of staph
becomes immune to antibiotics. The World Health Organization has said that in 10 years, antibiotics will no longer effectively treat bacterial diseases (Su, 2014). Selection of resistant microorganisms is exacerbated by inappropriate use of antimicrobials. Animal husbandry is the agricultural science of breeding and farming of farm animals. It is a source of resistance because sub-therapeutic doses of antibiotics are used in animal-rearing for promoting growth or preventing diseases. Injecting antibiotics
illnesses do not outweigh the risks associated with the massive overuse of them occurring today, with the most important risk being antibiotic resistance. Antibiotics were only recently developed, but have changed the world since their discovery. In 1928, a man named Alexander Fleming stumbled upon by accident a mold spore that seemed to kill the bacterial strains he was growing in petri dishes. He decided to investigate more into this, and eventually developed the first antibiotic, Penicillin. To
worldwide. What is antibiotics? — a chemical produced by fungi and bacteria, that inhibits with the biochemistry of bacterium fungi. Antibiotics many would say is a miracle drug, helping people to extend their life spans by altering the result of the bacterial infection. In the 1920s’ researchers speculated that the average populations life span age to be only 56 years old, now this number has increased significantly Antibiotic resistant bacteria have become a huge problem; because it is becoming more
longer replicate its DNA, keeping the bacterial population in check” (Guilfoile 2007). However, Ciprofloxacin resistance is over 30 percent in some species of bacteria. Furthermore it was concluded, “Overuse of Cipro could lead to the development of bacterial resistance to the drug, which would make it useless for treating infections”(Guilfoile 2007). In the late 1980s, about 5% of S. aureus strains were resistant. Accordingly, to avoid this rapid rise in resistance in the future, new drugs should be
differences between viral and bacterial infection will be exampled. Antimicrobial agents consist of antibiotic, antifungals, antiprotozoal, and antiviral. “Antibiotics are powerful medicines that fight