The Pros And Cons Of Umbilical Cord Blood

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Umbilical cord blood (UCB) is an important source of haematopoietic stem cell now being used for transplantation. It contains stem cells that are unique; smart and are capable of treating several diseases such as haemoglobinopathies, leukaemia, immune system deficiencies and many genetic diseases4. However, until recently in most cases the cord blood was discarded as medical waste, although now it is considered the hidden treasures of life. Since the first successful UCB transplant to a sibling with Fanconi anaemia performed in 1988 and cord blood have established worldwide6. Consequently, cord blood stem cells are currently used in the treatment of nearly 80 devastating disorder and it holds out hope for incurable disease. To date more than …show more content…

Therefore, many parents believe that banking umbilical cord is unique opportunity to save these stem cells in order to guarantee 100% match for their baby in case treatments is ever required6. One of the few disadvantages of this source of stem cells, there are limit amount of haematopoietic stem cells that can be extracted from each cord blood units. In addition, the UCB cells take longer to engraft than do stem cells from more mature sources. This delay leaves the recipients vulnerable to infection. In spite of certain disadvantage cord blood has huge potential in medical treatments3. Likewise, donating cord blood is generous gift that basically doesn’t cause harm or problem to the donors and may save or improve quality of someone’s life4. However, UCB stem cell donation and preservation are endorsed by many world religions. Though, there are many ethical concern including proper informed consent, genetic screening of the donors, autologous & allogenic UCB storage, truth in advertising by private banks and distributive justice6. In addition to cord blood banking, the expectant parents also have a chance to store their new-born baby’s cord tissues. Umbilical cord tissue (Wharton’s jelly) is rich source of umbilical cord mesenchymal stem cells (MSCs)10. It has abilities to self-renew and differentiate into many tissues cellular tissues including adipocytes, osteocytes, chondrocytes, cardiomyocytes, hepatocytes and nerve cells. Their proliferative properties have abilities to migrate at site of inflammation which makes MSCs highly desirable for tissue engendering and cells based

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