Homostasis is an organism's process of maintaining a stable equalibrium of various internal systems, and can be influenced by the body's internal and external environments. In most homeostasic processes, this equalibrium is achieved through the use of negative feedback systems, which ensure that blood glucose concentration is maintained within a very narrow range around an optimal value (known as the 'set point'). This means that whenever a change in the environment is detected, corrective mechanisms are activated which act to reverse the change and so bring the system back to the set point; at which point the corrective mechanism is switched off to prevent any further change. Any homeostatic process that changes the direction of the stimulus …show more content…
Very low concentration of blood glucose (hypoglycemia) can result in seizures, loss of consciousness, and eventually death; and a long-lasting high concentration of blood glucose (hyperglycemia) over a long period of time can result in nerve damage, heart disease, eye damage, and kidney failure. Therefore, the concentration of glucose in the blood must be maintained within a narrow range around the set point. In the human body this is generally 5.0mM of glucose in the blood. The process of keeping blood glucose within this set point is known as 'glucose homeostasis.' Glucose homostasis relies on the balance and interactions of two antagonistic hormones - insulin and glucagon. These are responsible for controlling the concentration of glucose in the …show more content…
These include endocrine cells called the islets of langerhans; and in the islets of langerhans are the alpha and beta cells. The liver is also an essential componant in this homeostatic system because it acts as a storehouse for glucose in the form of glycogen (the storage form of glucose, made up of many connected glucose molecules). Glycogen is also stored in muscles. Glucose can also be converted to fat and stored in the fat cells. During periods of hypoglycemia, the alpha cells sense that blood glucose concentration is too low below the set point of 5.0mM (as a result of heavy exercise or a lack of food) and then increases blood glucose levels by secreting glucagon, which is a hormone that helps raise the concentration of glucose in the blood. Glucagon stimulates the release of glucose from glycogen; it does this by breaking down the glycogen stored in liver and muscle cells and fat stored in fat cells into individual glucose molecules. Glucagon also stimulates the breakdown of amino acids into glucose. In this way glucagon raises blood glucose concentration back to the set point. Beta cells sense when blood glucose concentration rises too high above the set point of 5.0mM (for example after digesting a meal) and then decreases blood glucose levels by secreting insulin,
The beta cells affect a person’s glucose regulations within the blood. This is because the beta cells are in charge of sending insulin arou...
Our body obtains the energy by digesting the carbohydrates into glucose. Volumes of glucose are required by the body to create ATP. ATP is short for 'Adenosine Triphosphate ' and is an energy carrier. When we consume too many carbohydrates our body produces a lot of glucose and as a result blood glucose levels rise and sometimes they may rise over the normal range of blood glucose concentration. To bring it back within the healthy range, the homeostatic system of blood glucose regulation is used. The blood flows through the pancreas where the beta cells, receptors, detect the high blood glucose level. To counteract this stimuli beta cells alert the control centre, which are also the beta cells located in the islets of Langerhans in the pancreas. The secretion of insulin has to be done quickly but can only be carried out when insulin gene is switched on. Turning on the insulin gene switch can take 30 minutes to an hour therefore, the production of insulin by beta cells are done in advance and are packaged in vesicles right until blood glucose rises. Glucose comes into the beta cell to trigger the vesicle that contains the insulin to move towards the plasma membrane and fuse. This releases the insulin into the bloodstream where they are distributed throughout the body and only affect specific target cells. The receptor, a protein, on the target cell’s plasma membrane recognises and connects
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
In our body’s we have thousands upon thousands of cells that work together to maintain the whole structure. Although cells accomplish different roles, they all are comparable in their metabolic conditions. Preserving a continuous inner environment with what the cells require to survive like sugar, minerals, oxygen and waste removal is essential for the cells and host well-being. The diverse process that the body controls its inner environment are referred to as homeostasis. Homeostasis refers to maintaining a stable environment in reaction to environmental changes. The body’s inner environment requires constant observation to maintain a stable inner environment this way if conditions occur they can be adjusted. Homeostatic regulation is the adjustment of systems in the body. “Homeostatic regulation involves three parts or mechanisms: 1) the receptor, 2) the control center and 3) the effector.” (Wikibooks, para. 2)
The pancreas is composed of exocrine and endocrine tissues. The exocrine portion of the pancreas synthesizes and secretes pancreatic juices. The endocrine portion is composed of miniscule islands of cells, called the islets of Langerhans. These islets of Langerhans do not release their secretions into the pancreatic ducts. Instead, they release hormones into the blood stream, and these hormones in turn help control blood glucose levels (Function of the Pancreas). Beta cells of the islets of Langerhans secrete insulin, which
...on dioxide, within the body, affecting the pH balance of the blood. This will then affect proteins within the body, being known as enzymes, which can only function if their surrounding environment is in balance. Any alteration to this environment, will prevent the enzymes from functioning effectively.
Glucose is a sugar that plays a big part in a human’s health and well-being. This sugar is a major source of energy for the body’s brain and cells. The Cells that receive energy from glucose help in the building of the body’s muscle and tissue. Although glucose may be important to the body too much of this sugar can cause a chronic condition called Diabetes. Diabetes, also known as Diabetes mellitus, is a chronic condition that is caused by too much sugar in the blood. This condition can affect all age groups. In fact, in 2010 a survey was taken by the National Diabetes Information Clearinghouse, on the number of newly diagnosed diabetes. Out of 1,907,000 people: 24.38% were ages 20-44, 55.17% were ages 45-64, and 20.45% were ages 65 and greater. Diabetes is a very serious condition, and it can be deadly if left untreated. This paper will help better educate the reader on the signs and symptoms, the testing process, and the management of diabetes.
When the blood glucose is higher than the normal levels, this is known as diabetes disease. The body turns the food we eat into glucose or sugar and use it for energy. The insulin is a hormone created by the pancreas to help the glucose get into the cells. The sugar builds up in the blood because either the body doesn’t make enough insulin or can’t well use its own insulin (CDC, 2015). In the United States diabetes is known as the seventh leading cause of death. There are different types of diabetes. However, there are two main types of diabetes and these are; Diabetes type 1 and Diabetes type 2 (CDC, 2015).
When the blood sugar levels aren’t normal, it’s a disease called diabetes. Diabetes (diabetes mellitus) is a deficiency of the hormone insulin or the inhibition of its action with the cells. The insulin acts like a bridge between the glucose and the cells. In the US there are about 16 million people who suffer from diabetes. It is the seventh most common cause of all deaths. Diabetes is most common in Native American females over 45 years of age.
Homeostasis is a system that is needed to regulate the internal parts of the body such as temperature or bone homeostasis. The process of homeostasis is important to ensure the internal body is kept stable and to keep the conditions within the body the same as this allows the body to function properly.
In this assessment I will be discussing the process and purpose of homeostasis in our body and how this system acts to control our blood glucose level.
Blood glucose levels are the measurement of glucose in an individual’s blood. This is important because glucose is the body’s main source of fuel and the brains only source of fuel. Without energy from glucose the cells would die. Glucose homeostasis is primarily controlled in the liver, muscle, and fat where it stored as glycogen. The pancreas is also a significant organ that deals with glucose. The pancreas helps regulate blood glucose levels. Alpha-islet and beta-islet pancreatic cells measure blood glucose levels and they also regulate hormone release. Alpha cells produce glucagon and beta cells produce insulin. The body releases insulin in response to elevated blood glucose levels to allow the glucose inside of cells and
The pancreas, in addition to its digestive process has two important hormones, Insulin and Glucagon which are important for the maintenance of blood glucose level at a narrow range. Not only glucose, but also they are important for protein and lipid metabolism. Glucagon is secreted by the alpha cells of the islet of Langerhans and Insulin is secreted by the beta cells of Langerhans. Both are secreted to portal vein. (8)
Homeostasis is the maintenance of a constant internal environment within a living organism. Excretion is the removal from the body of waste products made in the cells during metabolism. Osmoregulation is the homeostatic control of body water. Water intake needs to balance with water loss. Urea is instantly converted from ammonia, as it is a less soluble and less toxic compound.
The pancreas uses these two hormones in order to monitor blood glucose levels. After a meal, blood glucose usually rises. This is when insulin secretion will start (Nussey S, Whitehead S. “Endocrinology: An Integrated Approach”). Consequently, blood glucose decrease to the normal range. This is how insulin maintains blood levels when is high. However, when blood level falls below normal range, glucagon comes into play. Low blood glucose occurs usually when hungry and during exercise. This will then triggers glucagon secretion. When blood level falls, the body goes into imbalance. Hence is why in order to maintain homeostasis glucagon is crucial. The body will tell the pancreas to increase more glucose and the pancreas will secrete glucagon by taking glycogen from the liver to produce glucose. The glucose will produce energy and will make blood glucose concentration increase (Homeostasis of Insulin and Glucose, Abpischools.org). When the pancreas cannot maintain homeostasis, many problems will arise in the body. When the pancreas fails to produce insulin, type 1 and 2 diabetes can occur. For those with type 1 diabetes, insulin injections will be needed in order to regulate blood glucose level, otherwise, glucose levels will be out of control. For type 2 diabetes, they are not insulin dependent like type 1, however, the body does not create enough in the body. When blood glucose