Sulforaphane is a molecule that has been used in the medical community, over the years, for many medical issues. Sulforaphane is a compound commonly found it vegetables, primarily broccoli. While sulforaphane is a major staple in medical treatment, limited studies have been done regarding the molecules effects on lung development. Premature birth with underdeveloped lungs is a serious problem that is sadly very common. A possible way to help speed the lung development process is by using sulforaphane. By feeding broccoli with sulforaphane to developing tadpoles, and studying their growth rates in relation to tadpoles that are not given the broccoli, it can be observed whether the molecule sulforaphane can actually help excelarate lung development …show more content…
When consuming broccoli for the benefits of sulforaphane, heating must be neutralized. While minimal heat will help the molecule's production occur more rapidly, the overuse of heat will deter the engagement of sulforaphane in the intended organism; furthermore, research indicates that freezing agents lead to the obliteration of Myrosinase. Fresh broccoli is ten times more rich in sulforaphane than frozen broccoli. After an organism absorbs sulforaphane, it begins to help the organism's body in a number of ways. This molecule is an antioxidant, has anti-aging properties, detoxifies the human body, and most notably, is used in the treatment of cancer. In a UCLA clinical trial, doctors found that due to the work of sulforaphane and Phase II enzyme RNA, cellular oxidative stress went through major shutdown; this in turn lead to the disarmament of asthma. "Several studies have analyzed the biological and molecular mechanisms of the anti-cancer activity of synthetic R,S-sulforaphane, which is thought to be a result of its antioxidant properties and its ability to inhibit histone deacetylase enzymes" (Marc A. Riedl, Andrew Saxon, and David Diaz-Sanchez 2011, April 6). Moreover, it has been concluded that sulforaphane can help fight aging by stopping the oxidation of free radicals. Although free radicals will always be absorbed, sulforaphane is one known molecule that can deplete the amount present in humans. Sulforaphane …show more content…
By feeding broccoli with sulforaphane to developing tadpoles and studying their growth rates in relation to tadpoles that are not given the broccoli, it can be observed whether the molecule sulforaphane can actually help excelarate lung development. While sulforaphane has been linked to the lungs through asthma and lung cancer, the study of its effects on lung development are quite limited; consequently, there are many lung diseases and conditions with the scientific potential to be linked with sulforaphane. Some such conditions include, but are not limited to: Respiratory Distress Syndrome, Pneumothorax, Bronchopulmonary Dysplasia, and Apnea of
Most of the time, it is from smoking. The tissue in the lungs will become inflame and produce mucous because of exposure to these chemicals. Theophylline and ß2 agonist will act to relax and dilate the airways and allow more oxygen to enter. They will also decrease the lungs sensitivity so that they do not react so much to inhaled chemicals.
Mrs. Jones has a history of COPD. She was already taking albuterol for her illness and it was ineffective when she took it that day. Mrs. Jones had been a smoker but had quit several years ago. According to Chojnowski (2003), smoking is a major causative factor in the development of COPD. Mrs. Jones's primary provider stated that she had a mixed type of COPD. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) was established to address the growing problem of COPD. The GOLD standards identify three conditions that contribute to the structural changes found in COPD: Chronic bronchiolitis, emphysema, and chronic bronchitis. A mixed diagnosis means that the patient has a combination of these conditions (D., Chojnowski, 2003). Mrs. Jones chronically displayed the characteristic symptoms of COPD. "The characteristic symptoms are cough, sputum production, dyspnea on exertion, and decreased exercise tolerance." (D., Chojnowski, 2003, p. 27).
One of the main focuses of the iron lung was to save patients who contracted the disease Poliomyelitis. Poliomyelitis, Polio, affected a patient’s breathing due to damaging paralysis in their lungs (“Poliomyelitis...
It all began in and around the year 1919. Sula Peace, the daughter of Rekus who died when she was 3years old and Hannah, was a young and lonely girl of wild dreams. Sula was born in the same year as Nel, 1910. Sula was a heavy brown color and had large eyes with a birthmark that resembled a stemmed rose to some and many varied things to others. Nel Wright, the daughter of Helene and Wiley, was and unimaginative girl living in a very strict and manipulated life. Nel was lighter in color than Sula and could have passed for white if she had been a few shades lighter she. A trip to visit her dying great-grandmother in the south had a profound effect on Nel’s life. In many ways the trip made her realize her selfness and look at things around her in a different light, eventually sowing the seeds that initiated the friendship between herself and Sula. The two girls met each other at Garfield Primary School after knowing each other at a distance for over five years. Nel’s mother had told her that she could not interact with Sula because of Sula’s mother sooty ways. The intense and sudden friendship between them which was to last many years was originally cultivated my Nel. The period in history and the mentality of the people in their immediate surroundings played an impressive part in the formulation of the friendship between Sula and Nel. When they first met at school, it was as if they were always destined to be friends.
Houghton, A. M. (2008, October). Common origins of lung cancer and COPD.Nature Medicine [serial online]. doi:10.1038/nm1008-1023
Another study proposed that CR slowed aging process by increasing resistance to hyperoxidation. As aging progressed in yeast and other animals, the presence of free radicals increased in the cells. Usually, the levels of the...
Omega-3 fatty acids are beneficial to everyone, whether they are still in the womb or 100 years old. The fatty acids are passed from mother to child via breast milk (as well as through internal fluids), a process which increases brain growth, serving as a building block for nerves and eyes in newborns and fet...
Cancer of the lung was nearly nonexistent in the early 1900’s. By the middle of the 20th century an epidemic became apparent throughout the United States and the rest of the world. It is primarily correlated with the widespread abundance of cigarette smoking in the world. The tobacco industry has multiplied its production immediately prior to World War I. There was a typical 20 to 30 year lagging period between the initiation of cigarette smoking and the actual tumor formation in the lungs. Lung cancer is the cancer that originates in the tissues of the lungs. It occurs when cells in the lung start to grow rapidly in an uncontrolled manner. Lung cancer can start anywhere in the lungs and affect any part of the respiratory system. Most of all lung cancer cases start in the lining of the bronchi (health-cares.net, 2005). It is the leading cause of all cancer deaths in the world. During this time the tobacco companies would continue to say that cigarette smoking was not addictive and did not cause any type of cancer. Even with all evidence in the world today about tobacco causing cancer, Tobacco companies still remain the most profitable business in the world. Lung cancer is very common in both women and men. Women account for about 40 percent of the lung cancer cases in the world. Women who smoke are more than twice as likely to develop lung cancer as those of men who smoke (Tavor, 2005).
Masks and personal protective equipment were not worn by the factory workers. With no preventative measures taken, workers respiratory tracts were exposed to cotton, flax, and hemp dust. This exposer caused side effects such as chest tightness, shortness of breath, long term respiratory diseases (COPD), and permeant loss of lung functions. These symptoms were later classified as a syndrome called byssinosis before disease were diagnoses. According to the online article, “Long term respiratory health effects in textile workers,” there were two obstructive lung diseases textile workers exhibited, Asthma and COPD. The article states that two hundred and twenty-five newly hired textile workers were studies and found to have increased in asthma like symptoms at a one year follow up. The article continues to explain that there was an increase in incidence of chronic and progressive dyspnea, cough, and sputum production characteristic of COPD seen textile workers on year follow up as well. Another lung problem seen in some textile workers per Dr. Edward Holmes interview in 1818 was Scrofula, known today as
There are many factors that are integrated into the successful development of a child from Prenatal growth into toddlerhood. Teratogens (outside factors) have a great impact on the babies’ inutero development. Some outside factors like second-hand smoke, smog, or fumes from cleaning chemicals can cause negative effects on the child inside the womb. A few major affects from teratogens could result in low birth weight, head circumference, slow physical growth as well as an effect on mental, behavioral and motor skills (Berk, 2003). The environment around the mother provides many of these outside factors affecting the baby’s growth. But the main link to teratogens during the gestation period is most likely the mother. Daniel S. Messinger and the National Institute on Drug Abuse found that 2.8% of pregnant women admitted to using illicit drugs during their pregnancy (1996). Through illicit drug use, tobacco use and alcohol use, the mother disrupts her baby’s growth with possibly permanent damage.
thought to be important to the development of the brain and other things.- (Definition of DHA)
Husain, A., (2010), The Lung, Robbins and Cotran Pathologic Basis of Disease, pp. 677-737, Philadelphia: Saunders Elsevier
Parker, Steve. "Chronic Pulmonary Diseases." The Human Body Book. New ed. New York: DK Pub., 2007.
Chronic bronchitis is a disorder that causes inflammation to the airway, mainly the bronchial tubules. It produces a chronic cough that lasts three consecutive months for more than two successive years (Vijayan,2013). Chronic Bronchitis is a member of the COPD family and is prominently seen in cigarette smokers. Other factors such as air pollutants, Asbestos, and working in coal mines contributes to inflammation. Once the irritant comes in contact with the mucosa of the bronchi it alters the composition causing hyperplasia of the glands and producing excessive sputum (Viayan,2013). Goblet cells also enlarge to contribute to the excessive secretion of sputum. This effects the cilia that carry out the mechanism of trapping foreign bodies to allow it to be expelled in the sputum, which are now damaged by the irritant making it impossible for the person to clear their airway. Since the mechanism of airway clearance is ineffective, the secretion builds up a thickened wall of the bronchioles causing constriction and increasing the work of breathing. The excessive build up of mucous could set up pneumonia. The alveoli are also damaged enabling the macrophages to eliminate bacteria putting the patient at risk for acquiring an infection.