Postoperative Analgesia

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We concluded that postoperative analgesia was best in intranasal fentanyl group, sedation was maximum in intranasal ketamine group and adverse effects although minimal, were mostly observed in intranasal ketamine group. Intranasal fentanyl group showed good cardiovascular stability during perioperative period as compared to the other two groups.
Fentanyl and ketamine both produced significant post-operative analgesia in good number of patients without any significant adverse effects. Hence they are recommended for use in post-operative analgesia by intranasal instillation in nasal endoscopic surgeries.
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