There exists a medical condition called Hemophagocytic lymphohistiocytosis or in shorter terms, HLH. Hemo means blood, phagocytic is to engulf and remove foreign material, lymph is the name of the fluid in lymphatic system, histiocytosis is the increase in the number of histiocytes.
There are various types of cells in the human body that fight off infection. A histiocyte is a cell found in the blood all over the body and is created by bone marrow. These cells fight infection and damage any foreign material. In a case of a person with HLH, they over produce these white blood cells. The extra cells made then increase in tissues and cause the liver, spleen, lymph nodes, or spinal cord organs to be damaged (What is HLH).
Symptoms include high fever, abnormal blood tests, enlarged spleen, skin rash, and enlarged lymph nodes. The Central Nervous System disease could occur in 50 percent of HLH patients. These symptoms often include seizures, irritability, fatigue, sudden blindness, coma/paralysis, weakening of face/eye nerves, weight loss, jaundice, and coordination difficulty. Also, bleeding is at high risk due to a lack of platelets or known as thrombocytopenia. If this is the case, the patient will be given a platelet transfusion to increase the clotting cells in the blood (References.) According to a population based study, HLH is estimated to happen in one in 50,000 births (Our mission). This disease is found the most in young children and infants (Office of Rare Diseases Research). It occurs under age one in 70 percent of all HLH cases (Our mission). This condition is rare and probable to lead to fatality.
In 1952, HLH was first identified as a familial immune dysregulatory disorder of childhood known as “familial hemophago...
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...n order to obtain money for HLH, corporations, foundations, or individuals are donating (Our Mission.)
Works Cited
"Blood." Blood. N.p., n.d. Web. 19 Feb. 2014.
"Experts at Treating HLH." Experts at Treating HLH. N.p., n.d. Web. 19 Feb. 2014.
"Liam's Lighthouse Foundation - Liam's Lighthouse Foundation - Home." Liam's Lighthouse Foundation. N.p., n.d. Web. 03 Feb. 2014.
"Office of Rare Diseases Research (ORDR-NCATS) | Supports Rare Disease Research and Information." Office of Rare Diseases Research (ORDR-NCATS) | Supports Rare Disease Research and Information. N.p., n.d. Web. 03 Feb. 2014.
"Our Mission." Raising Awareness about Histiocytic Disorders. N.p., n.d. Web. 03 Feb. 2014.
"REFERENCES." Treatment and Prognosis of Hemophagocytic Lymphohistiocytosis. N.p., n.d. Web. 19 Feb. 2014.
"What Is HLH?" Http://www.wch.sa.gov.au. N.p., n.d. Web. 19 Feb. 2014.
Many people have begun to question how they use the money they raise. About 81% of their funds are put towards their programs and services, while more reputable charities are usually
• Hemolytic disease of the newborn. Hemolytic disease happens when a mother 's disease fighting system (immune system) attacks her baby 's red blood cells. Proteins (antibodies) in the mother’s blood destroy the baby 's red blood cells. Two conditions can cause hemolytic disease:
"The Unofficial Liam O'Flaherty Homepage - Biography." The Unofficial Liam O'Flaherty Homepage - Biography. N.p., n.d. Web. 12 June 2014.
The job of the immune system is to keep “foreign” invaders out of the body, or if one gets in, to seek it out and kill it. These foreign invaders are called pathogens, which are tiny organisms that can cause an infection in the body. Pathogens can be bacteria, parasites, and fungi (http://www.niaid.nih.gov/topics/immuneSystem/pages/whatisimmunesystem.aspx).
In acute hepatitis one would see clinical symptoms more in adults than infants or children. Approximately fifty percent adults will not show any symptoms (CDC, 2017). Some clinical symptoms are nonspecific malaise,
Haemophilia is used to describe a collection of hereditary genetic diseases that affect a mammal’s body’s capability to control thrombogenesis. Thrombogenesis is the way in which blood clots which is an important role in haemostasis. Two common forms of haemophilia are A and B. (1) Someone with A (otherwise known as classic haemophilia), clotting factor VIII is does not exist enough or is entirely absent. A person with haemophilia B (otherwise known as Christmas disease), clotting factor does not exist enough or is also entirely absent. Those with the disorder do not bleed a lot they just simply bleed for a longer period of time. All people with haemophilia A or B are born with the disorder as it is a hereditary disorder and passed down through generations very few cases of haemophilia are not genetic and are therefore rendered a spontaneous gene mutation which is then passed down.
Hepatitis is inflammation of the liver. There are currently five known viruses that cause can hepatitis (Microbiology, 10e). The hepatitis C virus (HCV) is transmitted through contact with the blood of an infected person; however, it is now more commonly spread among IV drug users that share needles. Healthcare workers are also at risk for contracting HCV, but with standard precautions, the risk is low. “Prior to 1992, some people acquired the HCV infection from transfusions of blood or blood products. Since 1992, all blood products have been screened for HCV, and cases of HCV due to blood transfusion now are extremely rare. HCV can be passed from mother to unborn child. Approximately 4 out of every 100 infants born to HCV-positive mothers become infected with the virus. A small number of cases are transmitted through sexual intercourse; however, the risk of transmission of HCV from an infected individual to a non-infected spouse or sexual partner without the use of condoms over a lifetime has been estimated to be between 1% and 4%. There have also been some outbreaks of HCV when instruments exposed to blood have been re-used without appropriate disinfection.” (Microbiology, 10e)
Hemophillia is a rare bleeding disorder in which the blood does not clot normally. Hemophillia is usually inherited and people born with it have little or no clotting factor (a protein needed for normal blood clotting). These proteins work together with platelets to help the blood clot. When blood vessels are injured, clotting factors help platelets stick together to plug cuts and breaks on the vessels. Hemophillia usually occurs in males with about 1 in every 5 000 males being born with the disease each year. A hemophiliac does not bleed more intensely than a person without it but can bleed for a much longer time. In some severe cases, continuous bleeding occurs after minor trauma or can even happen spontaneously.They may also bleed inside their body(internally), especially in the knees, ankles, and elbows. The bleeding can damage organs and tissues and may be life threatening. There are two main types of hemophilia: A and B. People born with type A are missing or have low levels of clotting factor VIII (1 in 5 000 males). People born with type B are missing or have low levels of clotting factor IX (1 in 20 000 males). About 8 out of 10 people who have hemophillia have type A. The greatest concern for both types is deep internal bleeding and bleeding into joints. Hemophilia is a life long disease, but with proper treatment and self-care, most people maintain an active productive lifestyle.
Due to the fact that people are genetically predetermined to either have the Rh factor or not, sometimes there is an occurrence where a woman who is Rh⁻ is pregnant with a child who is Rh⁺. Problems can then arise if the blood from the baby enters the mother’s bloodstream; the Rh⁺ blood from the baby causes the mother’s body to create antibodies against it. These antibodies will then attack any Rh⁺ blood cells. This causes no harm to the mother but can create complications with the baby if the antibodies pass to it and destroy some of its blood cells. This is what is referred to as isoimmunization; it only occurs if the baby’s Rh⁺ blood enters the bloodstream unless a woman becomes sensitized to Rh blood when she received an incompatible ...
Hepatitis In modern society when a person gets sick with the flu or a cold they will usually go about their normal routine with the exception of a sneeze or a cough throughout the day. Sometimes things can be more than what they appear to be. The symptoms start out like the flu with coughing, fever, aches, and vomiting. However, the disease gradually worsens with symptoms of extreme weakness and excruciating abdominal pain. By then it is usually too late when the person finds out that their liver is failing and that there disease is caused by one of the most contagious, dangerous and deadliest of viruses. These viruses that were initially concealed by flu like symptoms are now known collectively as the disease of Hepatitis. The disease of Hepatitis is actually by six different types of viral infections, namely, Hepatitis A, B, C, D, E, and G. Hepatitis descries the destructive affect of the viral invasion of the body and liver by six and separate viruses. Each type of viral infection varies from one to another in degree of severity. The names of the viruses are in alphabetical order corresponding to their discovery. There is also a non-viral Hepatitis which is caused by substance. One rumor that has spread about hepatitis is that a person can only contract Hepatitis if associated with HIV or AIDS. This is not true! Any one can become infected with Hepatitis. Unfortunately this is about all most people know of Hepatitis. They need to know the full horror of which the virus is capable. The first of the Hepatitis viral infection to be discovered is Hepatitis A. Hep. A is the mild mannered virus compared to the other viruses. It has the symptoms of influenza, fever, vomiting, loss of appetite, and weakening of body, but it does have some differences such as jaundice (a yellowing pigmentation of the skin and whites of the eyes) and urine appears to be a darker color. Jaundice is caused by an abundance of bilirubon which has not been removed from the blood system due to the infected liver. Hep. A does not have any special medications or antibiotics that can be used to treat or prevent this unpleasant virus. Some ways of avoiding this viral infection include washing the hands very carefully and not eating food or drink of others. People living in the same house or having close contact should clean the area very thoroughly.
There is a disease spreading out in the world called Hepatitis C. It affects the liver and may cause the liver to fail. This disease is caused by a virus called Hepatitis C virus which is also known as HCV. About 32,000 people are affected with this disease per year only in the United States area. Some It’s a disease with many symptoms and many causes. of these symptoms are easy bruising, upset stomach and fever. These are just some of the many symptoms that come from the virus. Hepatitis Cs nature of the causative agent is determined by many things. The biological data of this disease is filled so much information. It is estimated that over 180 million people have gotten Hepatitis C and it is growing.
Bratton, R. L., Whiteside, J. W., Hovan, M. J., Engle, R. L., Edwards, F. D. (2008). Diagnosis
When a cell in our body has become infected or has become cancerous it’s surface changes. This is how the immune system can tell good cells from bad ones (the markings on the surface.) Once a bad cell has been recognized our bodies sends cells to destroy the damaged cell and prevent the spread of whatever caused the damage in the first place. The next step our body takes is to have the affected cells start to produce interferons and other helpful substances. These help to fight off unwanted organisms, and also to warn other cells of the invaders and prepare them to resist them therefore preventing the spread of disease.
According to this quotation, without white blood cells, also known as leukocytes, we would not be able to survive. White blood cells are our body’s number one defense against infections. They help keep us clean from foreign bacteria that enter our bodies. Statistics show that there are five to ten thousand white blood cells per micro liter of blood, however this number will increase during an illness. White blood cells can differ in many ways, such as, size, shape and staining traits. There are five different kinds of white blood cells that fall into two separate categories. One category is called, granular leukocytes, and the other is called agranular white cells.
There are various types of this disorder. It depends on gene factor relating to the child’s parents. The more altered genes, the more severe your condition. Hemoglobin particles are made of alpha and beta parts that can be affected by mutations. There are three major forms of this disorder that are categorized based on the severity of symptoms. They are minor, intermediate and major. Children with the minor or trait of the disorder do not experience any symptoms and may not require treatment. Children with the intermediate f...