Erythema Nodosum Case Studies

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Heather is a 26yo, G3 P1011, who is currently 24 weeks 2 days as dated by ultrasound. She is relatively healthy. She has one prior full-term delivery without complications. She was referred today to evaluate her lower extremities. Her issue started on Black Friday, when she came home from shopping, she noticed red areas all over her legs. It started as 4-5 but quickly developed into several on her bilateral shins. After a day or two they became nodules and then turned to discolorations such as bruises. During this time, she was evaluated in your office and there was concern for varicosities and possible phlebitis. She was started on Lovenox and an aspirin. She was seen by vascular surgery and there was no evidence of DVT’s. She was …show more content…

I did explain EIF to her. She did have a quad screen that was screen negative and in the setting of a normal anatomy, otherwise, the finding of a single EIF is of little significance. We spent the majority of the time discussing what I think is erythema nodosum given the history and description. Erythema nodosum is typically somewhat of an autoimmune/hypersensitivity reaction. Typically with immune complex it does deposit in the bilateral lower extremities. Pregnancy itself can be a precipitating factor for erythema nodosum. It is a self-limiting disorder but is occasionally treated with NSAIDs. Ideally we avoid NSAIDs in pregnancy. Currently, I think she is getting better from her prior flare, although she may have another flare in pregnancy and if so, you may consider treatment with prednisone 20 mg q a.m. for 10 days. I do think we can stop her Lovenox and I would change the full dose aspirin to a baby aspirin. I also noted in her thrombophilia work-up that while it appears that the full-work was ordered perhaps some of the test did not result due to the absence of a frozen sample. Because I think her risk for thrombophilia is low, I do not think you have to repeat these, but I informed Heather that in the future if anyone asks about her thromboph9ilai panel they may need to double-check with your office to know whether or not it was complete. For now, I do not think she needs to follow-up through

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