Aforementioned, there are many causes for cancer like pollutants, UV light, age, genetics, et cetera. But it may be helpful to know which risk factors are most likely to aid in developing certain types of cancer. For example, genetics and age are the main culprits for ovarian cancer while air pollutants, smoke and wood dust can lead to paranasal cancer. Lifestyle and environmental factors can also have an effect on the cancer. Though it can be difficult to identify which ones cause certain cancers because it may be hard to determine if someone has been exposed to something or not or if something they do is causing the cancer without actually testing it and proving that specific factor cancer causing.
Breast cancer and cervical cancer are a leading cause of death in women in the western countries. Drugs prescribed for both of them are now being challenged. So if we could understand the genetics of both these cancers and understand the pattern of inheritance of the mutated allele’s one could prevent these cancers (especially breast cancer) before its onset. Understanding the functions of lncRNA is important for knowing and treating cervical cancer. Also, finding out the faulty genes in both the types of cancers could be helpful for knowing the genetic pathway.
The number of genes varies by different tumors and locations in the body. Invasive cancer begins when the genetic changes allow the tumor to invade and take over certain tissues, and shed cells into the blood (lymph). When this occurs, the mass is then considered to be malignant. The rene... ... middle of paper ... ...s- which we would now consider immunotherapies because they aimed to attack disease with the body’s own defenses- brought about complete tumor regressions in some individuals. But they were not broadly accepted, because the results were unpredictable (What You Need To Know About Cancer, 101).
There are many different types of cancer and many different causes for the the disease. Most cancers are because of a genetic mutation. The most common type occur when a cell is dividing. Proto-oncogenes, which are alleles in a normal cells, mutate to form oncogenes. These oncogenes cause cancer because they do not allow the cells to self destruct or become epistatic.
This is a condition where internal bleeding occurs because the blood cannot clot, sometimes causing death. Although the therapeutic gene inserted helped in creating blood clots, there were still problems with the immune system rejecting it (ASGCT, 2011). The most popular disease being tested with human gene therapy is cancer. Of the trials with human gene therapy, two-thirds have to do with cancer (ASGCT, 2011).
Most believe it is in genetics and also that numerous environmental factors play a major role, but many doctors and scientists are still unaware of the cause of cancer till today. Cancer primarily starts to harm the body, shortly after damaged cells start to divide uncontrollably forming lumps or in other words, tumors, that may or may not be cancerous. There are patients diagnosed with lung cancer, breast cancer, stomach cancer and many more. In this paper, I would like to focus moreover on Brain cancer, a form of malignant cancer, my father was diagnosed with a few years ago, with all the treatments, and how it has affected his physical, mental, and emotional health. A common symptom of being diagnosed with a brain tumor is having usual seizures.
Colon Cancer Alliance ranks it as “the second leading cause of cancer-related death in the US” (“Colon Cancer Statistics”). Since the symptoms of colon cancer resemble symptoms of “other health problems,” colon cancer is not easily diagnosed without any physical testing (“What You Need”). Nevertheless, since “90% of new cases occur on people 50 or older,” testings, such as colonoscopy, can significantly reduce the chances of an individual having colon cancer (“Colon Cancer Statistics”). Most causes of colon cancer are age or dietary related, but genetics play an important role in causing colon cancer. Although further research into preventive method is still needed, existing treatments and ongoing researches hold great promises for the future.
It is very important that people take the time to understand exactly what cancer is, by knowing what cancer is it will make it easier to build a strong foundation of knowledge. What is the main cause of cancer? This question has been around since the first person to be diagnosed with cancer. There are many explanation and hypothesis to what causes this vast group of diseases. Cancer takes ahold of the body due to gene mutations but what causes these mutations is unknown, but it could be due to exposure to several differ... ... middle of paper ... ...conceptions-about-cancer/>.
Tumor-suppressor genes involve the BRCA1 and BRCA2 genes that are found in breast cells (Klugar & Park 2013). Certain mutations in each can increase the risk of ovarian or pancreatic cancer (Klugar & Park 2013). Most breast cancers are inherited, but they can also be acquired. Unlike proto-oncogenes, the American Cancer Society’s article on cancer states that most of the tumor-suppressor gene mutations are acquired instead of inherited. Acquired mutations of the TP53 gene code for the p53 protein and they appear in a variety of cancers, such as lung and breast cancer ("Oncogenes, tumor suppressor," 2011).
Cancer stem cells are a type of cancer cell that play an intimate role in determining the potential aggressive behavior of cancer. Cancer stem cells have taken the research world by storm, and although heavily debated, could potentially lead to the development of cancer therapies and impact the future of cancer treatment, or even a cure. In order to understand cancer stem cells, one must first understand stem cells in general. The idea of cancer stem cells was proposed over 100 years ago, but has recently become a major focus because of the similarities they share with normal stem cells. The idea of cancer stem cells generated research because sub-components of stem cells have been located in tumors of the breast, brain, and other organs.