Botox Treatment for Migraines

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A migraine is a form of severe headache that causes intense pain in a localized area of the head. Scientist’s speculate that the cause of migraines is genetic. Symptoms of migraines include: nausea, vomiting, sensitivity to light and sound, and aura (which is a disturbance of vision). These symptoms typically last anywhere from four hours to up to three days (Stroke, 2014). When a migraine occurs hyperactive nerve cells transmit impulses to blood vessels. This causes the blood vessels to contract and become narrower. After the blood vessels contract, dilation occurs and the blood vessels become large again. This is followed by “the release of prostaglandins, serotonin, and other inflammatory substances (WebMD).” These substances cause the pain that occurs with migraines. Without treatment migraines can be extremely painful and debilitating, making it nearly impossible to function in daily life (WebMD).

Botulinum toxin type A (BTX-A), also known more commonly as Botox, is a fairly new treatment option for those who suffer from migraines. A double blind case study using Botox to treat individuals who suffered from migraines proved to decrease occurrence, severity, duration, and symptoms of migraines. This study used three groups of people 25-U BTX- A, 75-U BTX-A, and the vehicle (or control group) to determine the effective amount of Botox and its positive treatment of migraines. These three groups were injected in several different areas of their precrainial muscles with their designated treatments. Patients assessed these treatments on a scale, with -4 as the most severe worsening and +4 as complete abolition of symptoms and occurrence. Additionally the patients kept daily journals of the headaches, frequency, symptoms, and dura...

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...ence with onabotulinumtoxinA (BOTOX) in chronic refractory migraine: focus on severe attacks. Retrieved March 23, 2014, from National Center for Biotechnology Information: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072485/?tool=pubmed

Silberstein, S., Mathew, N., Saper, J., & & Jenkins, S. (2000). Botulinum toxin type A as a migraine preventive treatment. For the BOTOX Migraine Clinical Research Group. For the BOTOX Migraine Clinical Research Group. Headache. , 40 (6), 445-450.

Stroke, N. I. (2014). NINDS Migraine Information Page. Retrieved March 23, 2014, from Migraine Information Page: National Institute of Neurological Disorders and
Stroke (NINDS): http://www.ninds.nih.gov/disorders/migraine/migraine.htm

WebMD. (n.d.). Your Guide To Migraines. Retrieved March 23, 2014, from WebMD: http://www.webmd.com/migraines-headaches/guide/migraines-headaches-migraines

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