Automatic Tumbler Mixer Essay

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1.MIXING OF POWDERS This may be achieved by initially mixing the active component(s) with an approximately equal volume of diluent(s). Further amounts of diluents, equal to the amount of material in the mixer, can then be added and mixed, the process being continued until all material has been added. Care must be taken to ensure that the volume of powder in the mixer is appropriate, as both over- and underfilling may significantly reduce mixing efficiency. The mixer used should produce the mixing mechanisms appropriate for the formulation. For example, diffusive mixing is generally preferable if potent drugs are to be mixed, and high shear is needed to break up aggregates of cohered material and ensure mixing at a particulate level. The impact Manual tumbler mixer/blender consists of the metallic vessel which is made up of stainless steel.The rotation of the vessel takes place manually without the power use, so by the slow rotation of the vessel,the mixing of the powders take place without sticking of the powders to the walls of the vessel. Automatic tumbler mixer also consists of metallic vessel which is made up of stainless steel but the rotation of the vessel takes place automatically with the power use, so by the slow rotation of the vessel the mixing of the powders take place without sticking of the powders to the walls of the vessel also.The baffles which are present in the vessel lifts the powder and falls over continuously. Shape of mixers Functions Shape of mixers Functions (a) Cubical shape It rotated about an axis causing the particles within the mixer to tumble over each other onto the mixture surface.To achieve a fast blending time ingredients are typically loaded top to bottom instead of side to side. (d)Cylindrical DIAGRAM FUNCTIONS -High-speed mixture-granulator can both mix and granulate a product,thus removing the need to transfer the product between pieces of equipment and thereby reducing the opportunity for segregation to occur. -The participate movement within the bowl tends to mix components quickly owing to high shear forces and the expansion in bed volume which allows diffusive mixing. Thirdly,mixing powders can be produced by using fluidized bed mixer. DIAGRAM FUNCTIONS -The main use of fluidized-bed equipment is in the drying of granules or the coating of multiparticulates). - Fluidized-bed equipment can, however, be used to mix powders prior to granulation in the same bowl. 2.MIXING OF MISCIBLE LIQUIDS AND SUSPENSION Mobile liquids with a low viscosity are easily mixed with each other.Similarly,solid particles are readily suspended in mobile liquids though the particles are likely to settle rapidly when mixing is discontinued.Viscous liquids are more difficult to stir and mix but they reduce the sedimentation rate of suspended particles. Equipment needed TYPE OF MIXERS FUNCTIONS and MECHANISMS (a)Propeller mixer - used to clamped to the edge of a

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