Atherosclerosis Essay

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Atherosclerosis, one of the leading causes of death in the country, is a condition in the arteries that is characterized by the deposition of plaque on the arterial walls. While the exact cause of atherosclerosis is unknown, it is a slow, complex disease that begins developing during childhood, and progresses faster with age.1 Certain factors such as smoking, obesity, high cholesterol, high blood pressure, and increased concentrations of sugar in the blood (or diabetes), play a role in the development of atherosclerosis by damaging the endothelium and inner layers of the arteries.1 Plaque begins to build up and harden in the areas where the inner layers of the arteries are damaged.1 These areas of plaque potentially rupture or burst, which encourages platelets to attack to the site of the injury and clump there, forming blood clots.1 These blood clots combined with plaque narrow arteries even more, which further limits the flow and delivery of oxygenated blood to the rest of the body.1 Atherosclerosis can ultimately cause a heart attack (blood flow to the heart is blocked), a stroke (blood flow to the brain is blocked), or angina (chest pain) depending on the artery damaged.1
Lifestyle changes include healthy eating, physical activity, managing stress, and quitting smoking. The medicine prescribed to patients with atherosclerosis is aimed at the factors that influence atherosclerosis, like statin medications to control or lower cholesterol levels and medications to lower blood pressure, blood sugar levels, or prevent the formation of blood clots or inflammation.2 The aim is to lower the lipid concentration as well as adding anti-inflammatory therapies, which can ultimately slow down the progression of atherosclerosis.3 However, these treatments are not able to completely inhibit the development or growth of these atherosclerotic lesions and only have a 30-40% efficiency

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