Antidepressant Drugs

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Patients who face an incurable depression for decades have had their symptoms disappear within hours of taking a low dosage of a highly addictive drug. Antidepressant drugs and behavioral therapies have been used to treat depression, but have failed to help people whom are resilient to the current treatment. The illegal party drug, ketamine, contains properties that can help alleviate depression and help people that have resilient characteristics. What worries many people to use ketamine as alternative method to help those who are not affected by the standard methods are how people currently abuse the drug. It creates a rising public health concern that there is an urgency to develop a more effective treatment that will delay the onset of depression …show more content…

Psychotherapy and antidepressant drugs are usually the most common method used together to treat depression. The most common antidepressant drugs that are used: Prozac (fluoxetine), Paxil (paroxetine), and Zoloft (sertraline) that have been used to treat serotonin, while Effexor (venlaxafine) and Remeron (mirtazapine) have been used to treat serotonin and norepinephrine. The antidepressant medications that are given are classified into different areas that affect different neurotransmitters in particular ways. Serotonin and norepinephrine are both used to ease depression by affecting neurotransmitters used to communicate between brain cells. The current treatments of psychotherapy and antidepressant drugs are failing to help people who have resilient characteristics that leave many patients lost and helpless. Current medications used to treat depression can take about two to six weeks after taking a therapeutic dose of the drug to see improvement, but many claim to feel better in few days. In those two to six weeks there can be many variables that can stray a person to show signs of improvement. The current drugs being used have been …show more content…

The rapid response of ketamine takes less time to see results then the current medication. Clark et all (2014) “provided a study that was conducted with a low dosage of ketamine made people experience dissociative effects after 30-40 min after administration, and the effects of the dissociative state were gone after 80 min. They found that this was because of the fast metabolism of the human body. After the dissociative effects declining, the depression signs had disappeared for 7 days. The results show that a person’s body reacts fast to the current low dosage and sustains the effects of the drug for a week” In animals studies conducted they used different models similar to the Forced Swim test on Mice showed that few models had fast responsive results and the effects of the drug last from 7 days (Forced Swim Test) to 21 days (Decreased Latency to feed in the Novelty suppressed feeding test). These findings showed that depressed actions were reduced through the actions of ketamine in rodent models. Both studies show rapid results that create an understanding that the drugs effect comes fast. The only down side that it leaves for many people to question what happens to the person during the time frame when the person is experiencing dissociative effects. People are worried about the people taking the infusion, will hurt them selves or hurt others when they are in the state of

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