Membranes in Biological Systems

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Membranes in Biological Systems Biology is never far from the headlines. You may not know it but biology affects our everyday lives in ways which would bore you! Have you ever wondered what a cell membrane or a cell was made of? Cells are surrounded by thin membranes; it is these cell membranes which separate inside from out, life from non-life. It is believed that a cell or plasma membrane similar those of today's cells defined the boundary of the first cell nearly 4 billion years ago. Since then, cells have evolved such that the plasma membranes and intracellular membranes now perform many functions: · Barrier: membranes keep the contents of the cell together, allowing nutrients to pass in but keeping out many harmful substances. · Signalling: membrane relays information about the surroundings of the cell to the inside and in the other direction. · Factory site: membranes provides places where enzymes can be arranged in an assembly line fashion. · Energy conversion: membranes allow light and chemical energy to be converted into more usable forms. · Subdividing the cell: in most cells, membranes separate different parts of the cell which perform different functions. · Recognition: different cell membranes have different surfaces and will interact differently with different other cells. This allows cells to `recognize' one another and act accordingly; human cells cooperate with each other while they may attack foreign cells including harmful bacteria. Cell membranes are about 5 nm thick whereas the cells range from about 5 µm to several meters for a Giraffe's nerve cell. Red blood cells (erythrocytes) are the most abundant and simplest cells in the human body. One obvious question is how red blood cells maintain their biconcave shape. It turns out that an understanding the properties of the cell membrane is necessary to understand the shape. It took nearly 100 years to uncover the structure of the cell membrane as it is now understood . In 1972 the 'fluid mosaic model' was proposed and is now accepted as the basis of our understanding of cell

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