Treponema pallidum 2 Introduction Treponema pallidum is a Gram-negative bacterium that has a spiral shape (1). They are about 6 to 20um in length and 18-20um in diameter (1). Treponema pallidum can only survive within a host which makes them obligate internal parasites, meaning that outside a host this organism will die due to the absence of nutrients, exposure to oxygen and heat. Also since this organism can’t be grown on a culture medium, animal models are used to study T. pallidum (1)
people each year and is the leading cause of stillbirths and deaths among newborns in many developing countries. 3 The causative agent of venereal syphilis is Treponema pallidum, under the Family Spirochaetaceae of the Order Spirochaetales. It is a spirochete, a helical to sinusoidal bacterium ranging from 5 to 15 microns in length. 2 T. pallidum multiplies by binary transverse fission and enter the body through mucous membranes (squamous or columnar epithelium cells) or minor breaks or abrasions in
All behavior and bodily functions are processed though interactions with the brain. In his book The Man Who Mistook His Wife for a Hat and Other Clinical Tales, Oliver Sacks discusses some of the ways that behavior is influenced for biological processes. The purpose of this paper is to evaluate a chapter of this book entitled Cupid’s Disease and explain the underlying biological and psychological processes experienced by Sacks patients. In the case of Cupid’s Disease, the behavior being discussed
knew the outcome syphilis would have on those men and they didn’t see any harm being done. “Syphilis is a highly contagious disease caused by the Treponema pallidum, a delicate bacterium that is microscopic in size and resembles a corkscrew in shape. The disease may be acquired or congenital. In acquired syphilis, the spirochete (as the Treponema pallidum is also called) enters the body through the skin or mucous membrane, usually during sexual intercourse, though infection may also occur
Syphilis is a sexually transmitted disease caused by spiral-shaped bacterium, Treponema pallidum.(PBS.Org). The sexually transmitted form of syphilis is caused by a corkscrew-shaped bacterium called Treponema pallidum, which is one of a closely-related group of bacteria called the treponomes. Other treponomes are responsible for the three non-venereal forms of syphilis, which primarily affect the skin and are most common in early childhood. Venereal syphilis probably mutated out of one of those other
frequently affected. Society negatively associates both diseases with promiscuity and prostitution. The diseases syphilis and HIV/AIDS have many similarities throughout history. Syphilis is caused by the spirochete bacterium Treponema pallidum of the subspecies pallidum. Treponema pallidum is not a zoonotic disease and therefore almost all cases of syp... ... middle of paper ... ... produces can be measured. (Chesney and Folkman, 1999) A positive result is identified by a polymerase chain reaction and
75% of people affected in the U.S. are men who have sex with men. Classification: Syphilis can affect either the nervous system (neurosyphilis) or the cardiovascular system (cardiovascular syphilis). Mechanism of disease in acquired syphilis Treponema Pallidum punctures mucous membranes or dermal abrasions and enters the blood and lymphatics to infect. The incubation period lasts from exposure to the appearance of the first lesions at the site of inoculation (this is from 10 to 90 days but generally
Although there are no over-the-counter (OTC) medications to treat or cure syphilis, if diagnosed early, it can be easily treated and cured. For most cases of syphilis, a single intramuscular shot of Benzathine penicillin G can be given to cure individuals during the primary and secondary stages of the disease. Receiving a series of three intramuscular injections of Benzathine penicillin G over a specified period can treat those in the latent stage of syphilis (CDC, 2016a). Those individuals who have
At the forefront of one the most deeply engrained legacies in modern history, Christopher Columbus triggered a centuries-long drama of colonization, in which the Europeans would mould the Western Hemisphere through the profit motive of entrepreneurial conquistadors and the expansionism of crusading Christianity. Coined by the historian Alfred W. Crosby, “The Columbian Exchange” represents a series of affairs followed by the discovery, which would ultimately shape the World as we know it
Chancroid is a rather contagious sexually-transmitted disease caused by a bacterial pathogen Haemophilus ducreyi. According to the Centers for Disease Control and Prevention (CDC), a probable diagnosis is established if there is one or more painful genital ulcers, typical presentation with regional lymphadenopathy, no evidence of syphilis, and a negative test for herpes simplex virus. A history of sexual intercourse followed by the formation of painful ulcers on genitalia, as well as the development
been a deadly disease affecting populations across the globe for hundreds of years (Tampa et al. 2015). Despite its prevalence, very little was understood about the disease until the 20th century; in 1905, the organism that causes syphilis, Treponema pallidum, was discovered by a Prussian zoologist named Fritz Schaudinn (Souza 2005). Only four years later, in 1909, a German scientist named Paul Ehrlich and the members of his lab discovered a cure for the disease, originally named Ehrlich 606 due
Sexually Transmitted Disease have been around for centuries and have continued to play a role in the worldwide and public health of many lives today. Additionally, In this research paper I will be discussing the SexuallyTransmitted Disease known as Syphilis. The purpose of this research paper and the significance of the topic I chose is to share information with you about the sexually transmitted disease. Aa well as, encourage individuals to make responsible and appropriate sex practices to avoid
Syphilis Syphilis is a sexually transmitted disease caused by the spiral bacteria called Treponema pallidum. Syphilis consists of three main stages, primary stage, secondary stage, and latent stage. The latent stage may lead to a final stage called the tertiary stage. There are many cures to syphilis, and it is virtually eliminated from today's society. There are a few ways to contract the disease, all of which can be prevented. The primary stage of syphilis is characterized by a small
Al Capone: Gangsters & Mafia in the 1920’s Al Capone (Alfonso or Alphonse Capone) was born in 1899 and passed away in the year of 1947. Once he had been brought up in New York City, Capone became connected with crimes and was the subject of murder investigations. In 1920 he moved to Chicago and became a lieutenant to John Torrio, a notorious gang leader. They established numerous speakeasies in Chicago in the Prohibition era. After eliminating his opponents, "Scarface" Capone took over control from
Syphilis is a sexually transmitted disease (STD) caused by Treponema pallidum pallidum. Syphilis can also be passed from mother to infant during pregnancy. Syphilis can cause massive damage to body if left untreated. Known as “the great imitator” because several of the symptoms of syphilis are similar to other diseases, making it hard to pinpoint Syphilis’ origin (what is syphilis). Scientists and other professionals have come up with multiple hypotheses for the suggested origin of syphilis. There
Ampicillin Ampicillin disrupts the third and final stage of bacterial cell wall synthesis by binding specific penicillin-binding proteins (PBPs) that are inside the bacterial cell wall. Then facilitated by bacterial cell wall autolytic enzymes, cell lysis beings. Ampicillin is metabolized by Hydrolysis of the B-lactam ring to penicilloic acid. Microorganisms such as salmonella, Escherichia coli, campylobacter, shigella aquificae, thermotogae, chrysiogenetes, nitrospira, deferribacteres, other eubacteria
“I’m an adult” is something we hear more and more lately. As we get older, it seems like the age where our population starts stating this perception is quickly becoming sooner and sooner. When one says that they are an adult, typically they mean they can make their own decisions. They are their own boss, which they interpret as the thought that they can do anything they want: Jobs, education, recreational activities, the list is quite long. But one item on the list that pops up more frequently is:
severe health diseases, which include tuberculosis, syphilis, hookworm, pellagra, and high death rate (Jones, Bad blood: The Tuskegee syphilis experiment, 1993). According to Jones (2008), “Syphilis is a highly contagious disease caused by the Treponema pallidum, a delicate bacterium that is microscopic in size and resembles a corkscrew in shape. Three stages mark the development of the disease: primary, secondary, and tertiary” (p. 2). In the author’s book, it identified the struggles that African
Name: Pubic Lice (commonly called “Crabs”) Causative Agent: Pthirus Pubis Clinical Manifestations: Symptoms do not normally appear until actually having pubic lice for about five days. Even after five days, some people just never get any symptoms. If symptoms do appear, they may cause: uncomfortable itching in the anus or genitals, fever, feeling under the weather, awareness of the presence of lice or small eggs, which are called nits located in pubic hair. Transmission: Pubic lice are easily transmitted
In 1932, in the area surrounding Tuskegee, Macon County, Alabama, the United States Public Health Service (PHS) and the Rosenwald Foundation began a survey and small treatment program for African-Americans with syphilis. Within a few months, the deepening depression, the lack of funds from the foundation, and the large number of untreated cases provided the government’s researchers with what seemed to be an unprecedented opportunity to study a seemingly almost “natural” experimentation of latent