Specific Purpose: After listening to my speech, my audience will know how alcohol was made and how it affects humans negatively and positively. INTRODUCTION I. Attention-Getter: Lance Penny once said “Alcohol is probably the easiest substance to abuse, because the potential is there. Its legal, and its available.” II. Personal Credibility: I have always wondered how alcohol was made and how it affects people differently. III. Establish Rapport: People all over the world drink alcohol as
those who don 't drink at all” (medical daily). Moderate drinking also protects against cardiovascular diseases by raising the level of high-density lipoprotein. Alcohol consumption improves factors that influence blood clotting, such as tissue type plasminogen activator. These changes could block arteries in the heart, the neck, the brain, ultimately many heart attacks and most recurrent types of
Nurse Leader Leadership does not always come with a title or prestige. Every nurse has within themselves qualities that make them a great leader. Leadership by definition, “is a combination of intrinsic personality traits, learned leadership skills, and characteristics of the situation (Cherry& Jacob (2013 p. 335). A leader is one who has the capacity and skills to direct or encourage others in efforts to achieve an outcome. I recently completed a self-assessment on my perceived leadership abilities
Emergency departments of hospitals are fundamental in the treatment of time sensitive conditions such as acute stroke (Trzeciak & Rivers, 2003). A stroke occurs when there is an interruption of blood flow to brain tissue, and therefore is a condition that relies on apt and adequate access to healthcare (Panagos, 2006). Patients who have experienced a stroke will most often present to emergency departments in order to receive treatment (Kothari et al, 1998). However it has been found by Chan et al
coagulation occurred in outer tissues. With the cut, cells get damaged, and more tissue factors, TF, are produced on the surface protein. This TF then binds to factor VII, form TF/VIIa complex, and it substrates into factor IX and factor X. With the intrinsic pathway slower but broader coagulation occurred within the damaged vessels. Factor XII is regularly circulates in the blood, but when the blood vessel gets cut, the blood flow into the tissue space. The collagens in the tissue activate the factor XII
clots, a cluster of blood that sticks together, are the cause of Ischemic strokes. Ischemic strokes also takes place when arteries become backed up with plague, leaving less blood to flow. Plague is cholesterol, calcium and fibrous and connective tissue that sticks to the walls of blood vessels. Ischemic strokes eternally damage the brain and cause a person's body to no longer function habitually.Some risk factors that may increase stroke are high cholesterol, diabetes, high blood pressure, and
formation of thrombus. Exposure of the subendothelial matrix of the plaque to blood due to superficial abrasion generates platelet activation and aggregation. Clotting factors on the platelet membrane carry out reaction which release prothrombin activator, this activator then converts prothrombin to enzyme thrombin. The transformation of fibrinogen to fibrin is then catalysed by thrombin. During proteolysis (the breaks down of protein), fibrinogen is converted to fibrin strands which stabilize the final blood
practice. References del Zoppo, G., Saver, J., Jauch, E., & Adams, H. (2009). Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator. AHA/ASA Science Advisory (40), 2945-2948. Lansberg, M., Bluhmki, E., & Thijs, V. (2009). Efficacy and Safety of Tissue Plasminogen Activator 3 to 4.5 Hours After Acute Ischemic Stroke. Journal of the American Heart Association (40), 2438-2441. Smith, W., Sung, G., Starkman, S., Saver, J., Kidwell, C., Gobin
(2015, September 1). Clinical policy: Use of intravenous tissue plasminogen activator for the management of acute ischemic stroke in the emergency department. Retrieved April 29, 2018, from https://www.guideline.gov/summaries/summary/49538/clinical-policy-use-of-intravenous-tissue-plasminogen-activator-for-the-management-of-acute-ischemic-stroke-in-the-emergency-department?q=alteplase Division for Heart Disease and Stroke Prevention
infection or tissue injury, which may lead to severe sepsis and septic shock if left untreated (Daniels, 2009; Robson & Daniels, 2013; Dellinger et al, 2013; Perman, Goyal & Gaieski, 2012; Vanzant & Schmelzer, 2011). Septic shock can be classified by acute circulatory failure as a result of massive vasodilation, increased capillary permeability and decreased vascular resistance in the body, causing refractory hypotension despite adequate fluid resuscitation. This leads to irreversible tissue ischaemia
more closely associate with medicine than the other three. In medicine, genetic engineering has been utilized for solving health problems. With genetic engineering, scientists are able to produce large quantities of insulin, interferon, tissue plasminogen activator, urokinase, human growth hormones, follistim (for treating infertility), human albumin, monoclonal antibodies, antihemophilic factors, vaccines, and many other drugs (Applications of Genetic Engineering). The medical advances due to genetic
the Journal of the American Medical Association stressed the importance of onset to treatment time as a factor in patient clinical outcomes. The study also indicated that early treatment of ischemic stroke with intravenous recombinant tissue plasminogen activator (rtPA) resulted in fewer deaths, intracranial hemorrhage, and an overall better prognosis for patients post-stroke (Saver et al., 2012). The clot-dissolving drug, also known as alteplase, is the only FDA approved medication for acute ischemic
But dialysis only cleanses the blood of wastes. Without a source of EPO, these patients suffer from anaemia. Now, thanks to recombinant DNA technology, recombinant human EPO is available to treat these patients, for treating anaemia, tissue plasminogen activator (TPA) for dissolving blood clots, angiostatin and endostatin for trials as anti-cancer
accumulate blood and compresses the brain tissue which can cause brain damage. There are 2 different types of strokes the first one is called a intracerebral hemorrhage stroke which is the most common of the two and is when an artery in the brain burst can compresses surrounding tissue in the brain. (CDC, 2010). The second form of a hemorrhage stroke is called subarachnoid hemorrhage which is bleeding in the area that is located between the brain and the thin tissue that covers it. (CDC, 2010). When it
Deep vein thrombosis (DVT) will happen when a thrombus (blood clot) forms in the deep veins in your body. The most common place of occurrence is the legs but can occur in other areas of the body. DVT may cause leg pain and/or swelling, but can occur without any signs or symptoms. Other signs and symptoms include; shortness of breath, rapid pulse, sweating, sharp chest pain, coughing up blood, and fainting.(mayo clinic) In the United States alone 600,000 new cases are diagnosed each year. It has
Epigenetics: The Effects of Lifestyle Choices on Genetic Factors Epigenetics can be defined through its own etymology: epi means on top of and genetic refers to our genes. Thus, epigenes are small chemical tags that sit on top of our DNA and chromatin with instructions for them. In order to best understand this concept, one must understand some fundamental truths about our DNA: Each person is born with a set strand of genes. What differentiates our cells from one another (say a blood cell from
delivering oxygen and nutrients to cells and removing cellular waste products. Perfusion is a normal physiologic process that requires the heart to generate adequate cardiac output to transport blood through blood vessels for distribution in the tissues throughout the body. The essential function of the cardiovascular system and pulmonary systems is to provide a continuous supply of oxygenated blood to every cell in the body (Pearson, 2010). Background Information The clinical experience used to
The purpose of treatment is to relieve his chest pain, maintain heart rhythm, decrease cardiac workload and preserve myocardial tissue. On recognition of STEMI signs and symptoms, John is administered with 300mg of Aspirin as a single dose, which is more than enough in order to achieve results within 30 minutes. As stated by Tiziani (2013), aspirin is an analgesic with an antiplatelet
“Will the human manipulation of DNA provide significant benefits to today’s society?” Human manipulation of DNA, also known as genetic engineering and recombinant DNA technology, is a process that involves combining DNA, and inserting the newly recombined DNA into cells to be expressed through protein synthesis. The human manipulation of DNA can be beneficial and disadvantageous. It allows genetically engineered (GE) proteins to be manufactured, aiding those with cardiac issues, and can increase
An ischemic stroke can occur in two ways. One of the ways in which ischemic stroke can happen is embolic stroke which occurs when a blood clot or plaque fragment forms somewhere in the body and travels to the brain. Once in the brain, the clot travels to the blood vessel small enough to block its passage. After that, the clots stay there and block the blood vessel which causes the stroke. About 15% of embolic strokes occur in people with atrial fibrillation (Ischemic stroke, 2016). In other words