The problem: Tuberculosis has been known to mankind since ancient times. Earlier this disease has been called by numerous names including ‘consumption’ (because of the severe weight loss) and ‘the white plague.’ Mycobacterium tuberculosis (the bacteria that causes TB), existed 15,000 to 20,000 years ago. In the 18th century in Western Europe, tuberculosis reached its peak with a occurrence as high as 900 deaths per 100,000.2 What is tuberculosis (TB disease)? Tuberculosis is a contagious airborne
major challenges due to the appearance of Multi-Drug Resistant Tuberculosis (MDR-TB) and more recently, the virtually untreatable Extensively Drug Resistant Tuberculosis (XDR-TB). MDR-TB are strains that are resistant to both top first-line drugs, Isoniazid and Rifampin, while XDR-TB are MDR-TB strains that are also resistant to any fluoroquinolone and one or more of 3 injectable drugs. With this new resistance, there emerges a great need to find new drugs that are as effective, yet bypass the problem
Treatment for Tuberculosis Tuberculosis has many forms that can invade the body. Many cures involve drugs and multiple combinations of the drugs. Drugs are used in combinations because tuberculosis can travel to different parts of the body. One of the causes for the spread of tuberculosis around the world is the emergence drug- resistance strain. Tuberculosis can become resistant to most, if not all, of the drugs that are used to treat tuberculosis. Tuberculosis is a bacteria infection
Tuberculosis (TB) is an infection that affects the lungs caused by an acid-fast bacillus M. tuberculosis (McCance, Huether, Brashers, & Rote, 2010, p. 1293). It is also considered as the leading cause of death from a curable infectious disease worldwide. It is highly contagious and the mode of transmission is by airborne droplets. A person can be exposed to the infection but not develop the illness, which is called latent TB infection. Unless the person is immunocompromised, some people remain asymptomatic
Drug-induced hepatitis is a common disease that affects patients taking certain type of medications. The presentation of these patients include jaundice, abdominal pain, nausea and vomiting.3 This case report will describe a middle aged gentleman with Acquired Immunodeficiency Syndrome (AIDS), Pulmonary Tuberculosis (PTB) and Hepatitis C who had just started on Highly Active AntiRetroviral Therapy (HAART) and had been rechallenged with antituberculosis drugs (anti-TB) who presented with signs of
INTRODUCTION Nature of the Bacteria Mycobacterium tuberculosis (M. tuberculosis) is the bacterium that causes the disease tuberculosis (TB). A distinctive characteristic of the genus Mycobacteria is the presence of a thick lipid-rich cell wall and resistance to the decolourization step of the gram stain (being acid-fast). The acid-fast characteristic of the M. tuberculosis is the result of a waxy, lipid-rich cell wall. The cell envelope of the tubercle bacilli contains a layer beyond the peptidoglycan
Throughout many years tuberculosis has atrociously affected the lives of many people. Many have suffered a horrible death due to this horrid disease. Tuberculosis is a highly contagious disease due to mycobacterium tuberculosis, which initiated about one hundred fifty million years ago. Skeletal abnormalities typical for tuberculosis were found in Egyptian mummies back in 2400 BC. In ancient Greece the Greeks seemed very familiar with tuberculosis only they called it Phtisis. Many years later a
Introduction: Tuberculosis is an infectious disease which causes millions of death in humans. In India approximately 500,000 deaths occurs now and then. TB is an air borne disease which is caused by Mycobacterium tuberculosis. Apart from M. tuberculosis, there are many strains of Mycobacterial species like M. bovis , M .africanum , M. microti, M. caprae , M. pinnipedi i, M. canetti and M. mungi. Together these species are known to be M. tuberculosis complex. The main target of tuberculosis is the
The patient has experienced fever, chills on body, headaches and anorexia as well as sweating especially during the night. The patient has also been feeling fatigued, muscle aches and nausea as well as vomiting especially after eating (WHO, 2010, p. 117). These symptoms started forty eight hours ago, and the patient has not taken any medication except for some aspirin. The patient has also been suffering from frequent fevers in the past two months. He has also suffered from frequent headaches but
Tuberculosis My hypothesis on Tuberculosis is that it is a very deadly disease that causes a persons lungs to fill with blood. This can harm the body by making the body suffocate itself when the lungs fill with blood. Tuberculosis is a bacterial infection that no one ever wants to encounter. This infection is very dreadful and can lead to death. Tuberculosis has been around for a very long time it used to be called “consumption” because the infection would consume who ever had the disease. Tuberculosis
“Human immunodeficiency virus (HIV) is a blood-borne virus typically transmitted via sexual intercourse, shared intravenous drug paraphernalia, and mother-to-child transmission (MTCT), which can occur during the birth processor during breastfeeding.” There is no cure for HIV or AIDS but over time different types of medications have been developed that slows down the advancement of the disease. AIDS is a lethal disease that is caused by HIV. HIV destroys the immune system and causes the body to not
Tuberculosis Prevention There are several ways to prevent tuberculosis. One is to control existing infections from those infected including people, pets, and cows. Unfortunately, more than 1/3 of the population has tuberculosis, making it hard to contain every case of tuberculosis. The BCG vaccine exists, but it is not very useful in countries like the US. The body’s defenses against tuberculosis are effective but fail once the immune system becomes suppressed. Antibiotics can be used to help
Mycobacterium belongs to phylum Actinobacteria and family Mycobacteriaceae. Mycobacteria are usually slightly curved or straig... ... middle of paper ... ...in 108 replications of Mtb. The likelihood of spontaneous mutations causing resistance to both isoniazid and rifampin is the product of these possibilities, or 1 in 1016. However, these biological mechanisms of resistance break down when chemotherapy is inadequate. In the circumstances of monotherapy, erratic drug injection, omission of one or more
Pneumonia and Tuberculosis Pneumonia and tuberculosis have been plaguing the citizens of the world for centuries causing millions of deaths. This occurred until the creation and use of antibiotics become more widely available. These two respiratory infections have many differences, which include their etiology, incidence and prevalence, and many similarities in their objective and subject indicators, medical interventions, course, rehabilitation and effects. To explore the relationship
Tuberculosis Tuberculosis (TB) is an infectious disease caused by a germ (bacterium) called Mycobacterium tuberculosis. This germ primarily affects the lungs and may infect anyone at any age. In the United States, the number of TB cases steadily decreased until 1986 when an increase was noted; TB has continued to rise since. Today, ten million individuals are infected in the U.S., as evidenced by positive skin tests, with approximately 26,000 new cases of active disease each year. The increase
Tuberculosis Tuberculosis is disease caused by a bacterium called Mycobacterium tuberculosis. Usually bacteria attacks lungs but TB bacteria can attack any parts of the body such as brain, kidney, and spine. It can spread through the lymph node and blood stream to any organ. Usually it is seen in the lungs. If it is not treated accordingly, it can be deadly. One of the leading causes of death in the United States was tuberculosis. Everyone who infected with TB bacteria not get sick. There are two
What is Tuberculosis, and how serious is this problem? TB, or Tuberculosis, is a chronic or acute contagious disease caused by a bacterial infection. TB is the leading cause of death from a single infectious disease, accounting for over a quarter of avoidable deaths among adults. It can affect several organs of the human body, including the brain, the kidneys and the bones, but it predominately manifests itself in the lungs where it is called "Pulmonary Tuberculosis". According to the WHO, TB infection
Historically, pediatric drugs have been used without the adequate research done for pediatric formulation and dosage information for children usage. There have been difficulties and lack of pediatric trials done on drugs and children received unapproved therapeutic uses based on adult formulation, which have caused harmful results in children. There is a profound need for pharmaceutical tests to be approved for safety and effective for use by children. Only few drugs have adequate labeling information
Arthritis What is the health problem? Most common types of arthritis: Osteoarthritis (OA), Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Fibromyalgia and Gout Arthritis is a joint pain or disease, that can also carry other side effects Joint arthritis symptoms include: swelling and pain, and an overall decrease in mobility Physical appearances may also be affected, and in some cases of joint arthritis, one might experience slightly bulky knuckles and joints Arthritis can also affect other
Tuberculosis TB is a disease that can cause a serious illness and can damage a person's organs. Every year more than 25,000 people in the U.S. are diagnosed with TB disease. That's only a fraction of the amount of people who carry the Mycobacterium tuberculosis. Mycobacterium tuberculosis is a rod-shaped bacterium. TB is spread through the air by carriers of the germ. People who breathe the same air can become infected with the TB germ. People who do work around or with people with the TB disease