Prevention and Control of Multi-Drug Resistant Organisms

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Introduction The Center for Disease Control and Prevention (CDC) defines multi-drug resistant organisms (MDROs) “as microorganisms, predominantly bacteria that are resistant to one or more classes of antimicrobial agents” ("Management of multidrug-resistant organism," 2006). The following list represents widely known MDROs: MSSA, or “Methicillin Sensitive Staphlococcus Aureus”, which responds well to typical antibiotics; MRSA, or “Methicillin Resistant Staphylococcus Aureus”. This bacterium also resistant to oxacillin and cefoxitin medications; VRE, or “Vancomycin Resistant Enterococcus”, bacteria resistant to vancomycin medication; CephR-Klebsiella, “Cephalosporin Resistant Klebsiella”, or any Klebsiella bacteria, that is resistant to ceftazidime, cefotaxime, ceftriaxone, or cefepime mediactions; CRE-Klebsiella, or “Carbapenem Resistant Enterobacteriaceae”, or any Klebsiella bacteria resistant to mipenem, meropenem, or doripenem medications; CRE-Ecoli, or “Carbapenem Resistant Enterobacteriaceae”, or any E. coli bacteria resistant to imipenem, meropenem, or doripenem medications; MDR-Acinetobacter, “Multi Drug Resistant” Acinetobacter bacteria - resistant to at least one agent in at least 3 antimicrobial classes of the following 6 antimicrobial classes: Table 1 ("Multi-drug resistant organisms," 2014). According to CDC approximately one out in 20 patients hospitalized in United States will contract a health care associated infection (HAI), many of which attributed to MDROs(3). The increase in numbers of patients becoming infected with MDROs makes prevention and control a priority in nation’s hospitals and health care stings. Table 1. ("Multi-drug resistant organisms," 2014)) β-lactam/β-lactam β-lactamase inhibitor combination ... ... middle of paper ... ...water physically displaces bacteria spores that are not reliably killed with alcohol-based hand rubs”(9). Hand should be washed for at least 15 seconds, covering all surfaces of fingers and hands; wash hands before and after any contact with a patient; before and after donnng steril gloves; before handling any invasive medical devise; after contact with any bodu scretions; after contact with equipment or other object near a patient; before eating; after using a restroom; if bacterial exposure is suspected. Conclusion Increase in MDRO s in acute health care settings is real and present treat to health and lives of patients and medical staff. Understanding of possible complications, education promotion on all levels and strict adherence to safe cleaning measures play a crucial part in managing MDROs and its prevention, as well as mortality rates and associated costs.

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