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Vaccines and their importance
Importance of immunization
Vaccinations and their importance to our society
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According to the Merriam-Webster Dictionary, a vaccine is defined as a preparation of killed microorganisms, or living, virulent organisms that is administered to produce or artificially increase immunity to a particular disease. There are approximately fifty principle vaccines utilized in the United States to prevent bacterial and viral diseases in humans. Disease prevention is a primary concern of public health in the U.S. Over the past two centuries, vaccines have been successful in preventing numerous cases of infectious diseases including: polio, measles, diphtheria, pertussis (whooping cough), rubella (German measles), mumps, and tetanus. In fact, it was a vaccine that was responsible for the eradication of smallpox, one of the most injurious diseases, in 1977.
The immune system plays a vital role in the fight against infectious diseases. It is capable of identifying pathogens that enter the body as foreign “invaders”, or antigens. This, in turn, signals the production of large, Y-shaped proteins called immunoglobulins (antibodies), which are used to pinpoint and neutralize these foreign substances. Vaccines contain the same antigens that cause disease; however, they are attenuated so that they are not strong enough to cause disease, but are able to stimulate the immune system to produce antibodies against them. In essence, vaccination protects against disease by triggering the immune response against a specific pathogen. Through vaccination, people are able to develop immunity without suffering from the actual diseases that vaccines prevent.
Herd immunity is described as the resistance of a population to infection and to spread of an infectious organism due to the immunity of a large percentage of a population. The lev...
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...faces. This is because, during transmission, HPV targets proliferating cells of the epithelium. Once inside the epithelial cell, the viral genome begins to replicate. Subsequently, the HPV particles that are released are able to infect a new host and the process repeats.
The “high-risk” potential of the HPV type is mediated primarily virulence factors which include E6 and E7 proteins. These proteins have been shown to bind to and degrade tumor-suppressor protein p53 and retinoblastoma (Rb) protein, leading to the inhibition of gene expression of normal cell division. The inactivation of p53 affects apoptosis of cells at the G0 checkpoint and results in cell cycle arrest. When E7 binds Rb, the Rb-E7 complex is degraded and the cells proceed to divide at an unregulated rate. This uncontrolled division is responsible for the malignant cells found in cervical cancer.
... when “HPV inserted its DNA into the long arm of her eleventh chromosome and essentially turned off her P53 tumor suppressor gene” (Skloot 213). This allows the cancer cells to produce monstrously virulent cells, making them hard to kill.
First off I am going to begin with the basics; what is a vaccine? Well a vaccine is a product that produces immunity from a disease it can be administered through needle injections, by mouth, or by aerosol. (Basics, n.d.) Sounds simple right well that leads people to wonder how do they work? They help develop immunity by acting as the infection, it is only acting as the infection so
Vaccines have been used to prevent diseases for centuries, and have saved countless lives of children and adults. The smallpox vaccine was invented as early as 1796, and since then the use of vaccines has continued to protect us from countless life threatening diseases such as polio, measles, and pertussis. The Center for Disease Control and Prevention (2010) assures that vaccines are extensively tested by scientist to make sure they are effective and safe, and must receive the approval of the Food and Drug Administration before being used. “Perhaps the greatest success story in public health is the reduction of infectious diseases due to the use of vaccines” (CDC, 2010). Routine immunization has eliminated smallpox from the globe and led to the near removal of wild polio virus. Vaccines have reduced some preventable infectious diseases to an all-time low, and now few people experience the devastating effects of measles, pertussis, and other illnesses.
The idea behind vaccines is to provide the body with just enough of the disease-causing substance to trick the body into producing antibodies against it. By injecting weak or dead infectious agents through the skin, it’s believed that the body will create the appropriate immune defense. Infants come into the world with antibodies they have gotten from their mother through the placenta. Infants who are breastfed continue to receive many important antibodies in the colostrum (the thick, yellowish premilk that is secreted during the first few days after a woman gives birth) and breast milk. During the first year of life, the immunity an infant gets from its mother at birth wears off. To help boost the fading ability to fight certain diseases, vaccines are given. Once the antibodies are produced, they stay around, protecting the child against the disease they were designed to fight.
While everyone has their own rights to their bodies and the bodies of their children, that does not mean that what they think is best for themselves or their children is best for the rest of the population they come into contact with. The majority of people associate vaccinations to babies and children under a certain age, but young adults and elders fall into the category of needing vaccinations. There is currently no federal law requiring adults or children to be vaccinated. Many positives come out of vaccinations to not only the individual, but also to the people they come in contact with. Currently there is an ongoing debate on whether or not vaccinations are safe and if they cause certain disorders in children. The risk of not getting
Disease has been known to humankind as the invisible killer for centuries. Plagues destroying towns, people dying for unexplainable reasons, and children dying all too soon. The miracle of modern medicine has permitted society to to have significant control over these terrifying invisible killer outbreaks. The vaccine is one of the greatest miracles of modern medicine. For example, the vaccine for the polio virus has virtually eliminated the incidences of polio in humans. “Vaccines represent a low-risk intervention administer according to a schedule in which there are currently no known acceptable alternatives.” (Opel et al. 2013). Vaccines protect the person who has been vaccinated from viruses and the more persons vaccinated the more
Vaccines are a training for your body helping it to learn how to fight disease without actually having the symptoms. Antibodies are created in response to a disease
Editor Noel Merino of Should Vaccinations Be Mandatory? states that, “Vaccination is the process by which pathogenic cells are injected into a healthy person in an attempt to cause the body to develop antibodies to a particular virus or bacterium” (Merino 7). Once the antibodies
A vaccination is the injection of weak disease-causing agents that help the body develop immunity against specific infectious diseases ("Why Are Childhood Vaccines So Important?"). It is through these vaccinations that children will develop immunity without suffering from the actual diseases that vaccines prevent ("Why Are Childhood Vaccines So Important?"). The field of medicine has come a long way. Vaccines are considered to be one of the public health’s greatest accomplishments to date. With the help of vaccines and public health, the overall goal is to prevent disease and promote health.
The purpose of vaccinations is to help the immune system handle the illness without exposing to the illness first as “Vaccines contain the same antigens (or parts of antigens) that cause diseases…the antigens in vaccines are either killed, or weakened to the point that they don’t cause disease...immune system produce antibodies that lead to immunity”("Why Are Childhood Vaccines So Important?") This means that Vaccines have the same pieces of a regular disease but has been manipulated in some shape or form that cannot infect the vaccine receiver. Almost as if the body is exposed to the illness already, but not quite like having the body fight off the disease but rather receive the ability to fight contact with any disease they are vaccinated against. Without vaccination, some illnesses can be fought off with the immune system alone, such as chicken pox and measles, and then would have the immune system protect by using the to fight against it. However, there are more fatal diseases, such as Polio, that has the ability to paralyze the body of anyone infected and even cause death if not treated right away
Vaccines are a type of substance used to stimulate the production of antibodies and help
By being vaccinated, the person is not only helping themselves but others around them too. Vaccines are an important tool for preventing disease and should be mandatory for all people. Childhood vaccines protect children from a variety of serious or possibly fatal diseases, including diphtheria, measles, meningitis, polio, tetanus, and whooping cough (Clinic Staff). By vaccinating children against diseases, it helps children grow into strong, healthy adults. Today, children in the United States continuously get vaccines that protect them from more than a dozen diseases (Childhood Immunization).
Each year, about 2.1 million people die from vaccine-preventable diseases. Many children may not receive their necessary first year vaccinations because of lack of availability, religious beliefs, and safety concerns (Healy, Rench, and Baker 540). The dictionary definition of a vaccine is a biological preparation that improves the immunity to a certain disease (Healy, Rench, and Baker 540). Although all 50 States in the United States require children to be vaccinated to certain diseases before entering school, the states also have exemptions for these vaccinations (Lu 870). Parents often choose not to get their children immunized, and it has proven harmful to the health of the global population. It is important for parents to have their children vaccinated against diseases such as measles, mumps, and polio because it is important to promote the welfare of the human race (Parkins 439).
Immunisation or vaccination is a very effective and safe form of medicine used to prevent severe diseases occurring from viruses and other infectious organisms and increase the amount of protective antibodies. It is given by drops in the mouth or injecting a person with a dead or modified disease-causing agent, in order for the person to become immune to that disease.
Vaccines boost your immune system by helping the body to create antibodies for a specific disease so that next time a real infection comes along, your body is prepared for the infection which in turn aids in antibody resistance. Biotechnology has provided tools for understanding virulence, which is the capacity of a microorganism to cause disease (virulence meaning: Collins English Dictionary 2014) and how microbial immunogens function, and secondly it offers new ways for creating vaccines (Fields and Chanock, 1989). Vaccines were first invented by Edward Jenner in 1796 to protect against smallpox, which involved taking a blister from a person who was infected with cowpox and then injecting it into another person’s skin (iaff.org, 2014).... ... middle of paper ... ...