Hypothesis: An increase in epilepsy resulting from premature birth indicates a less negative membrane potential at that developmental stage. Also, as channel proteins are synthesized and translocated to the axonal membrane over time, they may help establish a less negative Vm in later stages of development. Therefore, a less negative resting membrane potential is expected immediately following differentiation, and a gradual increase in charge across the membrane is expected to accumulate as the neu...
... middle of paper ...
...findings will be published and shared with the scientific community through the university.
Broader Impact: The experiment will attempt to add to the pool of knowledge regarding neurogenesis and physiological changes during the differentiation of neurons. It will also attempt to provide reasoning behind epilepsy in newborns, especially those born prematurely. According to the CDC, approximately one out of every 10 births in the United States occurs prematurely.8 This implies that an enormous amount of children every year are at high risk of suffering from epilepsy involving difficulty breathing and the possibility of loss of consciousness.8 If results are as expected, they could be used by hospitals and research institutions to implement strategies to prevent and treat epilepsy, decreasing suffering in newborns and reducing financial stress involved in treatment.
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