Why Is Toxoplasmosis Important To Humans

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Inhibiting Toxoplasmosis in humans by eliminating foodborne transmission through improved production practices, cat and rodent control Infections from Toxoplasma gondii are found in many human beings and animals used as a food source. All mammals and birds that are eaten by humans can function as intermediate hosts for T. gondii and therefore could potentially be the area of infection for humans. Many of the major sources of foodborne transmission to humans come from undercooked meat, mainly pork, wild game, and lamb containing tissue cysts. Other sources of T. gondii come from soil that has been contaminated with cat feces on raw fruits, vegetables and in water that contains the oocysts. There has been an increased interest from consumers …show more content…

Most human infections are obtained from either eating of tissue cysts in infected meat, products made by meat or by drinking water contaminated with sporulated oocysts that come from the environment or contact with cat fecal matter. The number of cysts found in skeletal muscles varies widely among different animals many of which are not all animals that are used for human consumption. It is also important to understand that seropositivity (The presence of antibodies or other immune markers that show prior contact to a specific organism or antigen (McGraw-Hill, 2002)) of animals that become meat may not show the risk these animals present for those that eat them. An example is with the meat of cattle and buffalo which rarely contain tissue cysts, however in some locations more than 90% of these creatures are seropositive for T. gondii. By contrast, seropositive pigs, sheep and goats have large quantities of tissue cysts in their meat (Tenter et al. 2000., Jones J.L., Dubey J.P., 2008). Pigs that have acquired Toxoplasma gondii are considered a significant source of infection for humans in the U.S. (Dubey, 1994). It is difficult to avoid exposure of pigs to T. gondii, therefore vaccination is considered to be an easy method for control. Vaccination with non-persistent strains of T. gondii is one of the approaches that has been used to reduce the prevalence of viable T. gondii in pig tissues (Dubey et al. 1998). Results from this study in 1998 showed pigs vaccinated with irradiated oocysts developed a protective immunity against clinical toxoplasmosis. The pigs that were vaccinated remained clinically normal whereas non-vaccinated pigs developed severe toxoplasmosis after being inoculated with a high dose of oocysts (Dubey et al. 1998). It seems that antibodies play a role in the ability of the body to have immunity however the mechanism of immunity brought on by feeding

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