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Research on crohn's disease
Research on crohn's disease
Research on crohn's disease
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Approximately 700,000 people in the United States suffer from Crohn’s Disease (crohnsandcolitis.com). Crohn’s disease is part of a group of conditions known as, inflammatory bowel diseases (IBD). Crohn’s Disease is a chronic inflammatory bowel disease. It most commonly occurs at the end of the small intestine; however, it can involve different areas of the digestive track. Some symptoms may include abdominal pain, weight loss, fatigue, and malnutrition. In 1769, an Italian physician named Giovanni Battista Moragni, made the first description of Crohn’s disease when he diagnosed a young man with chronic diarrhea. Later, in 1930, Dr Burrill B Crohn, whom the disease is named after, saw a similarity of the diagnosis in two of his patients. Two …show more content…
If your immune system is triggered, it effects the gastrointestinal tract, which causes inflammation that contributes to the symptoms. Things such as bacteria or viruses in the environment may trigger an abnormal immune response. Men and women are equally likely to be affected by the disease, and it can also occur at any age, but it is most common among people ages 15 and 35. “Because of the wide-ranging effects of IBD, multidisciplinary care of affected patients, both within and outside the hospital is essential.” (Rampton and Shanahan 5) Symptoms of Crohn’s disease may vary from person to person. Since Crohn’s disease is a chronic disease, patients will usually experience periods where the disease intensifies and causes symptoms, or periods where the patient doesn’t notice any symptoms at all. Many people that suffer from Crohn’s disease commonly experience loss of appetite and weight loss, which can lead to malnutrition. Malnutrition may cause damage to vital organs of the body. Abdominal pain is also common. Younger children with the disease may experience growth delay and development. In severe cases of the disease, a fistula may …show more content…
Other health problems of Crohn’s disease include anemia gall bladder or liver disease, and osteoporosis. Currently, Crohn’s Disease has no cure, but many treatment options can help you live a fulfilling life. The treatment of Crohn’s Disease may include, medication, surgery, and nutrition therapy. The anti-inflammatory medication is the most common medication used to treat people with Crohn’s. “Medication treating Crohn’s Disease is designed to suppress your immune system’s abnormal inflammatory response that is causing you symptoms.” (crohnsandcolitisfoundation.org) This will allow relief from symptoms such as fever and abdominal pain. Suppressing the inflammation also causes the intestinal tissues to heal. Oral 5- aminosalicylates, corticosteroids, and Humira are a few types of anti-inflammation medication. Sometimes people with Crohn’s are required to have a special diet given through a feeding tube or nutrients injected into a vein. This method can improve your overall nutrition and allow the bowel to rest. Resting the bowel can reduce inflammation. Maintaining a low fiber and dairy diet may also help. If medications and nutrition changes fail, the patient may have to undergo
in the upper GI tract. Gastric and duodenal ulcers can also result from Crohn’s disease and Zollinger-Ellison syndrome (ZES). The patient does not report a history of Crohn’s disease nor is he symptomatic for it. His symptoms do not indicate (ZES). ZES is a hyper secretory gastric acid disorder that results in multiple peptic ulcers, kidney stones, watery diarrhea and malabsorption.
Crohn’s disease is an inflammatory bowel disease. It is a fairly common disease that affects a large population causing abdominal pain, frequent bloody stools, and fatigue
“When I feel good (almost all the time), Crohn’s doesn’t affect school at all,” she said in an e-mail. “It’s when I get so exhausted that I have to miss a day of school. I feel guilty missing school, and depending on the time of year, I get so much work the next day that I have to make up.
“Crohn’s disease appears to be caused by a dysfunctional inflammatory response in the gastrointestinal tract” (U. S. News, 2009). Inflammation is the body’s natural way to heal by sending immune cells to the site of the injury or invader. Researchers think that this immune system response may be triggered by bacteria or viruses, material in the intestinal contents, or a defective signal from the body’s own cells, called an autoimmune response. Inflammation results in pain, heat, redness, and swelling of the tissue. Chronic inflammation can harm the function of tissues and organs (U.S. News, 2009).
Following a gluten free diet heals the damage to the intestines and prevent further damage (Rubio-tapia A). recovery may take two to three years in adults if they keep the consistence of their diet. Furthermore, setting up a schedule so that patient can get help for a registered dietitian. A support group may also help you cope the disease and diet (Rubio-tapia A).
Crohn’s disease is a disease that causes inflammation, swelling, and irritation to any part of the digestive tract which is also known as the gastrointestinal tract or GI tract. The disease most commonly targets the ileum which is a part in the small intestine. The digestive tract is organs that connect your mouth to your anus and it releases hormones and enzymes for the digestion in food. The inflammation caused by the disease goes deep into the lining of the digestive tract. It creates a stricture in the small intestine which is a narrowing of the pathway that can slow the movement of food through the intestine. The stricture can then move to large intestine which can cause many problems for absorption. When the disease causes the intestine to swell it can also be very problematic because the large intestine wouldn’t be able to function properly. Crohn’s disease is considered as an inflammatory bowel disease.
The purpose of Ulcerative Colitis medications is to reduce inflammation in the colon, therefore giving the tissue a window to heal.
Wakefield, A. J., Murch, S. H., Anthony, M. A., Linnell, J., Casson, D. M., Malik, M., Berelowitz, M., Dhillon, A. P., Thomson, M. A., Harvey, P., Valentine, A., Davies, S. E., & Walker-Smith, J. A. (1998). Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet, 351(9103), 637–641.
Anti-MAP therapy consists of 3 antibiotics known to kill the MAP bacteria. Hopefully this information has given you a little more insight into what is Crohn’s Disease. I would also like to say that Aimee Rouski has taken a huge step in not only spreading the word about the disease, but has also placed herself in a great position to continue to be an ambassador to continue spreading the word. Good Luck in using this platform to educate people, and assist others that are afflicted with Crohn’s, to have the courage to not feel the need to hide it.
Ondansetron showed a clinically effectiveness in changing the stool form and decrease the urgency of deification, but no improvement in term of pain. Also, it showed a well tolerated side effect that could be decrease by dose reduction. So, for patients with IBS-D who complain from stool urgency, ondansetron will be a great treatment options for them.
In rare cases when a patient does not respond to drug treatment or diet and lifestyle changes, surgery may be necessary. Doctors will remove part or all of the colon in attempt to stop the condition. Surgeries for UC are generally successful but significantly decrease quality of life because the patient has to deal with frequent stools due to the absence of a colon.
Inflammatory bowel disease is a life long disease, and it particularly targets the gastrointestinal tract (GI tract), which consists of the mouth, esophagus, stomach small intestine, large intestine (appendix, cecum, colon (ascending, transverse, descending, and sigmoid), and rectum), and anus. The gastrointestinal tract is very important to the human body; some of its functions include mechanical and chemical digestion of food, the movement of food and waste from mouth to anus, secretion of enzymes and mucus, and the absorption of nutrients. These are some reason why it’s so destructive when this part of the body becomes impaired or even damaged.
The human digestion system is very complex. It starts with the mouth, salivary glands, pharynx, esophagus, stomach, liver, pancreas, gallbladder, small intestine, large intestine, then ends/exits with the anus. Each step is essential to the whole system. For example, the mouth chews food and mixes it with saliva produced by the salivary glands, and then the pharynx swallows chewed food mixed with saliva, this is followed by the food traveling through the esophagus to the stomach where the food gets a bath and mixes with acids and enzymes. After the stomach, the liver, pancreas, and gallbladder produce, stores, and releases bile and bicarbonates. Bile is produced in the liver and aids in digestion and absorption of fat while the gallbladder stores bile and releases it into the small intestine when needed. Following the process into the small intestine, this is where nutrients will be absorbed into the blood or lymph (most digestion occurs here). Next is the large intestine this is where water and some vitamins and minerals are absorbed. Finally, it is the end of the road, the anus. At...
Gastroenteritis, sometimes referred to as infectious diarrhoea is a common disease that affects millions of people annually. It is a disease caused by viruses, bacteria or parasites that enter the human body and spread, which induce symptoms such as vomiting, diarrhoea, abdominal pain and nausea. Although it is a common occurrence in society and is usually not harmful, cases of gastroenteritis in less developed countries may have more fatal repercussions due to their inability to access ample means of treatment. Over time, as more research was conducted into the disease, scientific developments were made to aid those affected by gastroenteritis and reduce the number of fatalities by educating people regarding preventative methods.
Irritable Bowel Syndrome. Mayo Foundation for Medical Education and Research, 2014. Web. 20 May 2014.