Type V hypersensitivities are known as autoimmunity; defined as a state where the immune system reacts to the body's own cells, and can cause the stimulation, inhibition, or destruction of body tissues. It is sometimes presented as a subclass of type II hypersensitivity due to their similarities and type V being a later addition to the traditional classifications made by Coombs and Gell; though it is usually shown as its own class since it does not directly destroy cells but instead causes organ/tissue dysfunction. This is generally caused by lymphocytes whose job it is to recognize foreign substances, or antigens, and either destroy them or produce a protein known as an antibody which will recognize and either disable the target or flag it for destruction/removal.In the case of autoimmune diseases some lymphocytes recognize certain cells in the body as foreign and either attack them directly or produce antibodies which react to the body's own cells or cell components, and are known as autoantibodies. How the auto-antibodies react to the body’s cells varies between different conditions. Some well known autoimmune diseases are Graves disease, multiple sclerosis(MS), and rheumatic heart disease. …show more content…
It would appear that the lack of suppression in some certain individuals can cause an autoimmune disease to occur. This lack of suppression and therefore production of autoantibodies can in some diseases be caused by an infection(often in childhood): bacterial or viral. In most cases however the cause of these autoantibodies is unknown or thought to have a genealogical cause. There is a higher rate of autoimmune disease in women which indicates that it is potentially sex-linked(caused by genes on the sex chromosomes: X or Y) or that hormones hold some influence over the development of autoimmune
Hashimoto’s Thyroiditis is a condition where the thyroid gland is attacked by a variety of cell and antibody-mediated immune processes. It was discovered by Hakaru Hashimoto in Germany in 1912. This disease was the first to be recognized as an autoimmune disease. Hashimoto’s can lead to hypothyroidism, a condition in which the thyroid does not produce enough hormones in order to meet the bodies needs.
Researchers think that this immune system response may be triggered by bacteria or viruses, material in the intestinal contents, or a defective signal from the body’s own cells, called an autoimmune response. Inflammation results in pain, heat, redness, and swelling of the tissue. Chronic inflammation can harm the function of tissues and organs (U.S. News, 2009). Crohn’s disease also appears to affect certain ethnic groups more than others. American Jews of European descent are four to five times more likely to de... ...
My siblings and I have never received any vaccinations because my parents opted out of them. Up until second grade, I thought it was rare for people to get shots. I didn’t realize that vaccines were required to go to school and that I was in the minority. Now that I know this, I am meeting more people that aren’t vaccinated. For example, my next door neighbors have five children who aren’t vaccinated, and they homeschool. Similarly, my second cousins, have five children that homeschool and have not been vaccinated. This made me wonder if maybe not vaccinating a child fits into a view of life that includes homeschool and large families. Lastly, my sisters and I all had the Chickenpox when we were younger so I think we are immune to getting them again. I am curious whether beating the disease is better than just getting the vaccine.
Graves’ disease is an autoimmune disease that was discovered by Robert Graves in 1835. Graves’ disease is an autoimmune disease in which the body's immune system attacks the thyroid gland and causes hyperthyroidism. Graves’ disease occurs when the antibodies like thyroid-stimulating immunoglobulin and thyrotropin receptor antibodies (TRAbs) attack the thyroid gland as if it were a foreign object or a virus of some sort. This disease is the most common type of hyperthyroidism. Attacking the thyroid gland in such a manner makes it excessively overproduce the hormone thyroxine which controls the body’s metabolic rate. Heightened activity of the thyroid can increase the body’s metabolism by 60% to 100%. (Weeks 34-35).
“Immune Response: MedlinePlus Medical Encyclopedia.” National Library of Medicine - National Institutes of Health. Web. 18 Dec. 2011. .
Usually your body produces antibodies to fight off invaders such as Viruses or diseases but since Lupus is an autoimmune disease; the immune system can’t tell the difference between foreign invaders and healthy tissues. There 3 types of Lupus Systemic Lupus (most common) which can affect any part of the body, Discoid Lupus which only affects the skin, and Drug induced Lup...
The immune system is one of the major systems of the human body. It protects the body from diseases and infections that could cause harm to a person’s body. To protect the body it distinguishes between unhealthy and healthy cells (National Institute). The immune system distinguishes between these cells to determine if the body is being invaded by a disease, or if the body is fine and healthy. It will fight off foreign contaminants if they are invading the body to potentially harm it. The immune system works to suppress any unwanted cells, microbes, etc. Without a proper working immune system, the human population would constantly be sick.
Being allergic to something may not seem to be a big deal to some people, but to others it can be life-changing. When someone is diagnosed with an allergy, especially when the allergen (the thing that triggers the body to have its allergic reaction) is very common in her environment, she may have to make many lifestyle changes to stay safe and healthy. The first step to treating an allergy is to understand fully what the allergy really is and how to keep one’s self safe. So what is a latex allergy? A latex allergy occurs when the human body decides that latex is a harmful substance and tries to fight it off; causing multiple symptoms, and sometimes being very hard to avoid.
A big part of Dysautonomia is knowing what it is, its symptoms, and causes. First, Dysautonomia is an umbrella term which describes multiple problems throughout the body. Such as dysfunction of the autonomic nervous system which controls functions of the body like the cardiovascular system, gastrointestinal system, metabolic system, endocrine system. Those who get Dysautonomia have trouble regulating these systems. Second, Dysautonomia can be life threatening and ranges from mild to disabling. Those who have Dysautonomia report increased symptoms after illness, trauma, or immunizations and children tend to struggle more than adults with basic functions of life. Dysautonomia tends to affect more females than males; it has a female to male ratio of 5-1. This disease is not very well known or heard about in society because it is such a rare disease (“What is Dysautonomia? What Causes Dysautonomia?”). Third, Dysautonomia can be diagnosed in different forms and with other diseases. Most people get diagnosed with another disease along with Dysautonomia. Some of these diseases or conditions that Dysautonomia is diagnosed with are Diabetes, Rheumatoid Arthritis, and Parkinson’s disease. People can also be diagnosed in different forms such as; Neurally Mediated Syncope (chronic condition where blood pools and there is a decrease in blood pressure and heart rate), Pos...
Graves’ disease is considered an auto immune disorder. It is also a hyperthyroid disorder that leads to the over activity of the thyroid gland. Graves’ disease is a condition that occurs when the immune system mistakenly attacks healthy tissue. Many people suffer from symptoms. This paper will talk about the causes of the disease, research that has been conducted and how it can be treated.
In most situations, genetic heredity plays a role in what allergy a person acquires. Children inherit their allergy from their parents. (Mills et al., 2007) On the contrary, some of individuals develop certain allergies in spite of their parents. One proposed theory that will be explored in this paper is whether or not the use of vaccines causes us to develop certain allergies. Before that theory can be proven as right or wrong, we must first get a more thorough understanding of the immune system.
The exact cause of Lupus is still unknown, on the other hand, researchers are certain that females are prone to be diagnosed with Lupus. Woman especially between the ages of 15 and 44 years old. More importantly, Lupus has advanced among certain racial and ethnic groups: African American, Hispanic/latina, Asia, and Native American woman have a greater risk of developing Lupus. (“What You Should Know about Lupus,”n.d)
Human race is known to have developed numerous allergies to various known and unknown allergens. An extreme allergic reaction which can be “life-threatening”. (Mydr.com.au, 2014) is referred to as Anaphylaxis.It is a “medical emergency”(Lloyd & Sisman,2013).Statistics indicate that maximum deaths occur due to allergic reactions of various medicines. The other causative agents can be insects, food, latex, hair dye, etc(Lloyd & Sisman,2013). The most common trigger to stimulate anaphylaxis among children are food products such as peanuts, dairy, seafood etc. Exposure to any of these allergens can result in severe anaphylactic attack within 20 minutes.(Australian Resuscitation council, 2012).However the doctors discuss the history of symptoms occurring in children suffering with peanut allergy before declaring them to be anaphylactic and prescribing medication. (Unknown, 2014). Symptoms of anaphylaxis may occur in varied forms depending upon the severty of the reaction. For instance in mild cases swelling of lips, eyes or face occurs along with hives, rash, tingling of mouth and vomitting accompanied with abdominal pain. Nevertheless in extreme conditions the former symptoms may be accompanied with noisy breathing, wheezing, hoarseness and unconsciousness. (Lloyd & Sisman,2013).
One of the most common mysteries in the world is the development of autoimmune diseases. An autoimmune disease is when the immune system, which usually keeps your body healthy thinks that your healthy cells are antigens and attacks them. This is irony right? It is against properties of evolution for an immune system to attack itself causing sickness and possibly death if untreated. There are about 80 different types of autoimmune diseases, which usually have periods of little to no symptoms and worsening symptoms. What particularly creates confusion in the world is the autoimmune disease, inflammatory bowel disease, which affects almost about five million people worldwide.
Patients who usually have allergies suffer from many symptoms due to the allergic reaction(s). Normally, your immune system protects you against invading agents such as bacteria and viruses. Otherwise harmless allergens (allergy-producing substances) cause your body to react as if they were dangerous invaders. In effect, your immune system is responding to a false alarm.