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Question On Virology
Essay on the history of polio
Essay on the history of polio
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Poliomyelitis, also known as polio, was the most feared childhood disease of the first half of the 20th century. It was an acute viral disease which was caused by the inflammation of the motor neurons of the brainstem and spinal cord. In addition, being affected by the poliovirus caused paralysis of the body and sometimes even death. It was a disease that scientists could not find a cure for it. But at the peak of its devastation in the United States, a vaccine has been introduced to prevent it. As a matter of fact, there has been two versions of the polio vaccine developed during the 20th century. The first vaccine was known as the Salk vaccine, created by scientist Jonas E. Salk, that contained three types of inactivated poliomyelitis viruses and induced immunity against the disease. The second vaccine was known as the Sabin vaccine, created by scientist Albert B.Sabin, that orally administered live viruses for immunization against poliomyelitis. In results “ the Salk and Sabin vaccines quickly reduced the number of polio cases in the countries where they were used extensively” during the 20th century(Wilson np). But the most effective polio vaccine that impacted the world the most till this day was the Sabin vaccine.
The first vaccine was known as the Salk vaccine, created by scientist Jonas E. Salk, that contained three types of inactivated poliomyelitis viruses and induced immunity against the disease. It has impacted the the 20th century by reducing the number of polio cases around the world . It was the beginning of the medical revolution.The birth of the Salk vaccine was in 1947, when Salk began research at the University of Pittsburgh Medical School. Because “The National Foundation for Infantile Paralysis, aware of...
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... children to administer [polio] vaccinations , as a method that will be introduced to many countries targeted for depopulation”(21Wire np).
Works Cited
Bill Gates and Polio. 21WIRE MEDIA, 6 Mar. 2013. Web. 21 Mar. 2014. .
Hecht, Alan. Polio. Philadelphia: Chelsea, 2003. Print.
“Polio.” The History of Vaccines. College of Physicians of Philadelphia, n.d. Web. 19 Mar. 2014. .
What Happened to Polio? Smithsonian National Museum of American History, n.d. Web. 19 Mar. 2014. .
Wilson, Daniel J. “The End of Polio?” World History: Modern Era. N.p., n.d. Web. 19 Mar. 2014. .
In the United States there was a vicious enemy everyone feared. In the 1950s the United States was under attack by the ruthless Poliomyelitis virus. Americans lived in constant fear of their children contracting this horrible virus that left many children paralyzed. During the outbreaks in the 1950s foundations were created to fund research and create awareness to help find a way to eradicate the virus. Americans become focused on doing anything in their power to fight this virus off. Jonas Salk’s Exploration of Medicine and research led to the creation of the Polio vaccine that united the country, prevented further outbreaks, and introduced a new form of treatment which has limited the fatality of polio infections today.
At first polio was a troubling prospect when it first reared its ugly head in the United States of America. In a noble effort to be rid of polio, America as a whole was to adopt stringent sanitation measures. Everywhere, especially the home was to be spotless and clean in order to try and prevent the contraction of polio. This coupled with the view that America as a western nation seemed impervious to such a lowly disease tried to assuage American fear of the disease. Despite the measures commonly adopted throughout the myriad of cities and towns, polio still managed to spread around the country and wreak havoc taking thousands of lives. An outbreak that ravaged America claimed nearly 27,000 lives in a terrible reckoning before it finally subsided. This and several other troubling outbreaks
Health care policies are put into place regarding childhood immunization requirements for schools, along with information on obtaining religious exemptions. Each state and/or country develops their own individualized guidelines through interactions with federal and state government agencies. One in five babies around the world are missing out on basic vaccines and may die from weak health systems and insufficient funding. UNICEF and its partners are working to change these numbers and ensure that all children are successfully protected with vaccines.
The death rate was on the decline and life expectancy rose during this period. New medical developments were made with the federal funding of medical research in which penicillin and streptomycin were developed. These advancements in medicine have cured many bacterial infections and severe illnesses. Later, in 1952, Jonas Salk introduced a polio vaccine. There was a vast migratory pattern among many Americans during this time period.
One of the other notable important advances was the “Conquest of Polio” this disease usually caused paralysis in the people who contracted the virus. Back then there...
Vaccine safety is one of the most controversial topics in today’s public discourse. Everyone has heard of them, but few know why they are so encouraged. A vaccine contains a weak or dead version of a microbe. This creates a small scale invasion of the immune system, which activates cells to destroy the microbe. Once these cells have been made they are always there to provide protection. This protection is immunity, for those cells are then able to recognize any live version of the same microbe and attack it immediately. This can save lives but also be dangerous, vaccines carry many other components which can cause side effects. These could be simple adverse effects such as a small cold or, in the rare case,
Poliomyelitis is a virus that infects the nerves of the spinal cord, and brain which leads to paralysis and or death (Piddock, 2004). Poliomyelitis is best known today as Polio, and Infantile Paralysis. Tonsillectomy polio would take over the lymph nodes in order to spread the infection throughout the body, leading to muscle paralysis in the limbs, and in some cases respiratory failure. Bulbar polio was a much more severe form, it affected the top of the spinal cord which caused paralysis and inability to swallow fluids (Rifkind, 2005). Polio was transmitted through ingesting materials contaminated by the virus found in feces. Children would play in public swimming pools, and ingest the contaminated water which lead to infection (Piddock, 2004). After the person ingested the virus, it would travel their intestinal tract, and eventually compromise their lymph nodes, making them unable to fight off the virus. Symptoms were like those of the flu, such as fever, headache, and upset stomach. The minority of people were able to let the virus run its course and it would be passed through their feces like any other virus. Others weren’t so lucky, those with compromised immune systems were unable to fight off the virus, the lymph nodes would fail to protect the nervous system causing paralysis once it reached the spinal cord (Piddock, 2004). Poliomyelitis has since then been eliminated in the United States because of the polio vaccine that is giv...
Fifty-nine years after the vaccine was introduced to the world, the number of cases of outbreaks has dropped 99% and only three countries still remain in an epidemic state with the virus, Nigeria, Pakistan and Afghanistan. In 1994, the WHO Region of the Americas was certified polio-free and in in 2013 only406 reported cases were existent in the world, compared to the 350 000+ cases in 1988. (Who, 2014).
Vaccines have been used to prevent diseases for centuries, and have saved countless lives of children and adults. The smallpox vaccine was invented as early as 1796, and since then the use of vaccines has continued to protect us from countless life threatening diseases such as polio, measles, and pertussis. The Center for Disease Control and Prevention (2010) assures that vaccines are extensively tested by scientist to make sure they are effective and safe, and must receive the approval of the Food and Drug Administration before being used. “Perhaps the greatest success story in public health is the reduction of infectious diseases due to the use of vaccines” (CDC, 2010). Routine immunization has eliminated smallpox from the globe and led to the near removal of wild polio virus. Vaccines have reduced some preventable infectious diseases to an all-time low, and now few people experience the devastating effects of measles, pertussis, and other illnesses.
In Conclusion, Understanding Polio’s etiology, history and epidemiology, as well as proper treatments will assist in avoiding its return. Although polio has been known to substantially affect a wide population in a small amount of time, eradication of this disease may also be accomplished in a short period of time. Scientists and medical professionals continue to research this disease in order to better understand and maintain it for many years to come. There are still aspect of the disease people do not understand that may be vital for the future of a polio-free world.
Poliomyelitis, also known as Polio, is a highly contagious disease caused by a virus that attacks the nervous system. Most victims to this disease are younger than five years of age; they are more likely to get this disease than any other age group. Out of two hundred people infected with the polio disease one is most likely to result in paralysis. The Polio Virus has decreased greatly since the Polio Vaccine was developed. In 2010 a WHO (World Health Organization) pole reported only 1,352 cases worldwide. Since the Polio Vaccine was developed the U.S has not has a single Polio case since 1979.
Jonas Salk, a virologist at the National Foundation for Infantile Paralysis (NFIP), used inactivated viruses (virus particles grown in culture and then killed by a form of heat) to create a polio vaccine. Salk drew blood from about two million children, which the NFIP checked for immunization. Through the collection of many HeLa cells and trial and error, the polio vaccine was ready in a year.... ... middle of paper ... ...
Polio: An American Story describes a struggle to find a vaccine on polio through several researchers’ lives, and over the course of many years. The second thesis is the struggle between Salk and Sabin, two bitter rivals who had their own vaccine that they believed would cure polio. The author David M. Oshinsky, is describing how difficult it was to find the cure to a horrifying disease, which lasted from the Great Depression until the 1960’s. Oshinsky then writes about how foundations formed as fundraisers, to support polio research. Lastly, the author demonstrates how researchers were forced to back track on multiple occasions, to learn more about polio.
...of antitoxin and serum therapy in 1890. To get antitoxin, they immunized guinea pigs with heat-treated diphtheria toxin. They then discovered that they could cure diphtheria in animals by injecting the serum, blood products, from the guinea pig into the animal. Following the discovery of antitoxin, English physician S. Monkton Copeman discovered that adding glycerin to lymph makes it act as a germicide in 1891. The first big Polio epidemic will happen on June 17, 1894 in Rutland County, Vermont. Then, only 4 years after the discovery of the diphtheria antitoxin, Mulford Company of Philadelphia began to test and produce antitoxin in the US. Since there was no common standard for potency of an antitoxin container, each container had a different potency. To solve this, German scientist Paul Ehrlich developed a standardized unit of measure for the diphtheria antitoxin.
(Jane C Finlay, Noni E MacDonald, 2001). Working with Vaccine -hesitant parents. Canadian Paediatric Society. Retrieved May 3, 2013, from http://www.cps.ca