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Vitamin d deficiency eassay
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Vitamin D is important for the body’s health as it helps regulate the amount of calcium and phosphate in the body. Its main roles can vary from giving strength to bones by absorbing calcium, keeping teeth and muscles healthy and maintaining a healthy immune system. Sources of Vitamin D include sunlight and vitamin D rich foods. Vitamin D obtained from sunlight is then converted into a hormone known as calcitriol or activated vitamin D by the body. Vitamin D is a hormone which has a primary function to simply promote the use of calcium and phosphorus around the body (VanPutte, Regan and Russo, 2016). These nutrients are essential for healthy muscles, strong bones, bone healing, and teeth. Calcium homeostasis: Vitamin D plays a significant role in calcium and phosphate metabolism and also ensures a sufficient amount …show more content…
Parathyroid hormone ‘reabsorbs bone tissue’ which is what causes bones to become thin and fragile. (Cleveland Clinic, 2015) With an increase in vitamin D, the levels of parathyroid hormone decrease - which in turn keeps bones and teeth strong and healthy. Immune system: Vitamin D can regulate the ‘innate and adaptive immune responses’. Vitamin D receptors are ‘expressed on immune cells’ such as B cells, T cells and antigen presenting cells (Aranow, 2011). Pregnancy: During pregnancy and whilst breastfeeding, having adequate levels of vitamin D is essential to ensure that the developing baby is receiving enough calcium and phosphate - which are vital for the development of the infant. Vitamin D presents itself in 5 different forms D2 and D3 are the most common derived from cholesterol Vitamin D2 produced by plants is called ergocalciferol Vitamin D3 (chocalciferol) is made in skin. The skin is irradiated by ultraviolet rays from sunlight, which meets 7-dehydrocholesterol, as a result cholecalciferol is made. (Reaction in plants is similar and produces
However some of the basic bone functions include storing of crucial nutrients, minerals and lipids, producing red blood cells for the body, protect the organs such as heart, ribs and the brain, aide in movement and also to act as a buffer for pH. With the differences in all of the bones there are four things that remain the same in each bone, their cells. Bones are made up of four different cells; osteoblasts, osteoclasts, osteocytes and bone lining cells. Osteoblasts produce and secrete matrix proteins and then transport the minerals into the matrix. Osteoclasts are responsible for the breaking down of tissue. The osteoblasts and osteoclasts are both responsible for remodeling and rebuilding of bones as we grow and age. The production of osteoclasts for resorption is initiated by the hormone, the parathyroid hormone. Osteocytes are the mature versions of osteoblasts because they are trapped in the bone matrix they produced. The osteocytes that are trapped continue making bone to help with strength and the health of the bone matrix. The bone lining cells are found in the inactive bone surfaces which are typically found in
Papas, E., & Cluxton, R. J. (2011). Vitamin D: beneficial for pain, fracture, and falls in long-term care residents?. Annals of long term care, 19(5), 33-36.
In 2011, the University Of Minnesota took women who take vitamins daily and studied them(Offit, Paul., 2013). The result was the same in that there was no supporting evidence that favors Pauling’s claims and statements. In conclusion, the general public believed the words of a man who had no specific evidence to support his own claims over researches done by trusted establishments who had evidence towards their own claims against Linus Pauling. Vitamin D is essential in many aspects especially during growth periods such as adolescents and infancy as indicated by Winston Koo and Nitin Walyat who are the respective authors of “Vitamin D and Skeletal Growth and Development”. Vitamin D is essential for the body as it helps development organ cells; without the development of organ cells, the body cannot fight against harsh diseases and it will eventually cause severe diseases which can lead to delayed growth rate(Koo, Winston ., 2013, p.188).. Children who drink breast milk are more prone to vitamin D deficiency because breast milk does not contain as many vitamins as mineral (Koo,
Osteoporosis is a condition, which advances with age, resulting in fragile, weak bones due to a decrease in bone mass. Externally osteoporotic bone is shaped like normal bone, however it’s internal appearance differs. Internally the bone becomes porous due to a loss in essential minerals, including phosphate and calcium. The minerals are loss more quickly than they can be replaced and in turn cause the bones to become less dense and weak. The bones become prone to fracture, due to their weakness. Therefore the awareness of the disease tends to occur after a fracture has been sustained. The bones most commonly affected are the ribs, wrist, pelvis and the vertebrae.
Osteoporosis is a serious disease that leads to a faster than normal loss of the bone density, which puts the bone at a higher risk for fractures. In order to understand the causes of Osteoporosis, it is important to understand how bones are formed. Bone is a living tissue that is made mainly of collagen, calcium phosphate, and calcium carbonate. The mixture of collagen and calcium gives the bone strength and flexibility. The body deposits new bones and removes old ones; moreover, there are two types of bone cells that control the reproduction of bones. Cells called osteoclasts breakdown bone tissues thus, damaging the bone. Once the damaged bone is removed, cells called osteoblasts, use minerals including calcium and phosphate from the blood stream to make new healthy bone tissues. In order for osteoblasts and osteoclasts to work properly, hormones such us thyroid, estrogen, testosterone, and growth hormones are
...risk breast milk only has a very small amount of vitamin D. this was found as a problem also in the 16th centaury because it was normal for you child to drink mostly your milk two years into their life. An ABC NEWS reports looked at 380 kids below the age of 2 and 12% were deficaint in vitamin D and 40% dint have the desirable amount in their body, report by Dustin Lushing,. So although not many kid suffer from rickets it is still a problem in some areas that have a lack of education about the disease and how important the right amount of vitamin D is and sun in moderation.
Vitamin C, also known as Ascorbic Acid, has the structural formula C6H8O6. Vitamin C is an essential nutrient believed to have very important benefits to the human body and it enables the body to make efficient use of carbohydrates, fats, and protein. It is needed by the body to repair bones, teeth, and cartilage; heal wounds and scars; help the body absorb iron from certain substances, and promote a healthy immune system. Vitamin C is also needed to form collagen, which is a protein used to make skin tissue, blood vessels, ligaments, and tendons. Vitamin C is an antioxidant, meaning it protects the body’s cells against oxidation and the destructive effects of free radicals within the body. It is also believed that vitamin C helps to prevent
Vitamin D3 (ergocalciferol) originates from 7-dehydrocholesterol, a precursor of cholesterol when synthesized in the skin.3
Other metabolic bone diseases are osteoporosis, gout, OSTEOARTHRITIS, and PAGET'S DISEASE. Nutritional Disorders Nutritional deficiencies that result in bone damage include RICKETS in children and osteomalacia in adults, caused by a lack of vitamin D. In children, calcium and phosphate are poorly distributed on bones during development, resulting especially in deformity of the legs and arms. In adults, bones of the spine, pelvis, and legs become demineralized and the bones weaken.
Vitamin, any of the organic compounds required by the body in small amounts for metabolism, to protect health, and for proper growth in children. Vitamins also assist in the formation of hormones, blood cells, nervous-system chemicals, and genetic material. The various vitamins are not chemically related, and most differ in their physiological actions. They generally act as catalysts, combining with proteins to create metabolically active enzymes that in turn produce hundreds of important chemical reactions throughout the body. Without vitamins, many of these reactions would slow down or cease. The intricate ways in which vitamins act on the body, however, are still far from clear.
Calcium is a mineral found in many foods that the human body cannot produce itself (National Osteoporosis Foundation). According to the National Osteoporosis Foundation it is used in the regulation of heartbeat, stimulation of hormone secretions, conduction of nerve impulses, stimulation of blood clotting, and maintenance of a healthy skeleton. They also state that we lose calcium every day through shed skin, nails, hair, sweat, and other bodily functions. Bones are also constantly being “remodeled” by removal of older pieces of bone and replacement with new bone. These losses make a daily source of calcium invaluable. Calcium has traditionally been thought of in conjunction to milk, but this connection is slowly being broken.
Vitamin D is a necessary component for calcium absorption to prevent boss loss. Nutritionally our body can create vitamin D by sun exposure however many factors can prevent our bodies to create vitamin D such as using sunblock or not getting enough sun exposer from daily routine. Vitamin D can be found in many foods that we such as milk including almond milk, eggs yolks, saltwater fish, and liver. Other vitamins that can help prevent bone loss are vitamin A and C. Vitamin C is an antioxidant which helps reduce oxidative stress which can have a negative effect on the cells in the body. This helps protect against inflammation which takes away calcium from the bones. Vitamin C can be found in many foods such as papaya, bell peppers, broccoli, Brussel sprouts, strawberries, pineapples, oranges and kiwifruit and fruit juices have supplement vitamins. Vitamin A is important for bone growth, vision, cell division and cell differentiation. There are two different forms of vitamin A are retinol and beta-carotene. Retinol can be found in meat, poultry, fish and dairy products while beta-carotene can be found in fruits, vegetables and
Rickets is a bone disease that occurs in children as a result of a Vitamin D deficiency. This disease, which was nearly eradicated in the early 20th century, has become a re-emerging health concern for various countries in the past ten years. Certain factors such as poor nutrition as a result of low socioeconomic status or high concentrations of melanin in the skin can increase the chances of getting rickets. Sufficient Vitamin D levels are crucial to the functioning of the body, especially in the absorption of calcium. This essay will examine the causes, symptoms, pathogenesis, diagnosis and treatment of rickets; as well as the importance of Vitamin D and calcium in the prevention and treatment of this disease.
1. Stress. "A recent meta-analysis showed vitamin C was beneficial to individuals whose immune system was weakened due to stress -- a condition which is very common in our society," says Moyad. And, he adds, "Because vitamin C is one of the nutrients sensitive to stress, and the first nutrient to be depleted in alcoholics, smokers, and obese individuals, it makes it an ideal marker for overall health."
Vitamin D can often be obtained with two different methods. The main method is the conversion of 7-dehydrocholesterol in the skin into Vitamin D3 via sun exposure to absorb ultraviolet B radiation with a wavelength of 290-315nm (Holick 2007). The other method, is through consumption in diets through plants in the form of Vitamin D2; or fatty fishes, supplements or fortified vitamin D products in the form of Vitamin D3 (Lavie, Lee & Milani 2011). Vitamin D undergoes hydroxylation twice; first with the enzyme 25-hydroxylase to form 25-hydroxyvitamin D (Calcidiol) (Al Mheid et al. 2013). Then, Calcidiol is converted to the most active form of Vitamin D, 1,25-dihidroxyvitamin D Hormone (Calcitriol) with the help of renal 1--hydroxylase in the kidney (Al Mheid et al. 2013). Vitamin D2 and D3 are relatively similar since share the same hydroxylation pathway to produce Calcitriol (Tripkovic 2013), however, D3 has shown to have a greater influence on Calcidiol levels and thus more effective in maintaining Vitamin D health (Heaney et al. 2011).