Stereochemistry And The Theory Of Sterochemistry

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Stereochemistry come to the learning of the relative placement of atoms that form the structure of molecules and their use. An essential subdivision of stereochemistry is the learning of chiral molecules. Stereochemistry is also known as 3D chemistry because the prefix "stereo-" means "three-dimensionality”. The learning of stereochemistry centering on stereoisomers and spans the whole range of organic, inorganic, biological, physical and especially supramolecular chemistry. There is some grandness of stereochemistry. Firstly, is the thalidomide incident. Thalidomide is a medicament drug, first processed in 1957 in Germany, appointed for treating morning illness in pregnant women. The drug was revealed to be teratogenic, causing sincere genetic harm to early embryonic growth and development, leading to limb distortion in babies. Some of the several planned mechanisms of teratogenicity touch on various biological purpose for the (R) - and the (S)-thalidomide enantiomers. In the human body however, thalidomide undergoes racemization whereby justified if only one of the two enantiomers is apply as a drug, the other enantiomer is produced as a outcome of metabolism. Accordingly, it is wrong to state that one of the stereoisomer is harmless while the other is teratogenic. Next, the properties of many drugs rely on their stereochemistry. For information:…show more content…
Isomers are separated into structural and stereoisomers. Structural isomers are isomers that have the identical molecular formula but differ in structural formula, that is, in the order in which the opposite atoms are connected in the molecules. They have different IUPAC names, the identical or different functional groups, various physical properties and different chemical properties. Structural isomers are further separated into chain isomerism, position isomerism, functional isomerism, metamerism and tautomerism.
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