Periodontal Disease Research Paper

1085 Words3 Pages

Abdullah Chughtai 9/26/2015

Periodontal disease is an infection of the gum tissue that can cause damage to the tissues and the bone supporting the teeth. Periodontal disease is caused by the combination of bacteria and plaque to form a biofilm, which adheres to the tooth surface, resulting in inflammation. Periodontal disease is broken down into two stages, gingivitis and periodontitis. According to research, about 70 to 90 percent of people have some form of the periodontal disease. Periodontal disease has been known to increase in severity with age [1] and has shown to be the leading cause of tooth loss in many adults.
The first stage of periodontal disease is gingivitis. Gingivitis is an inflammation of the gums, and is referred …show more content…

Periodontitis results in destruction of the PDL, connective tissue and bone, which causes the creation of deep periodontal pockets between the teeth and gums. These pockets allow bacteria and plaque to thrive, resulting in the erosion of bone, and the subsequent loosening of teeth. Studies have shown that periodontitis results from a mixed infection of gram negative bacteria. These bacteria include A. actinomycetecomitans, B. forsythus, P. intermedia, T. denticola and P. gingivalis [4]. These bacteria play a role in periodontitis by colonizing plaque subgingivally, releasing toxic products (such as H2S, LPS), and activating the immune response. Activating the immune response results in the release of cytokines (such as TNF-alpha, IL-1, IFN-alpha) and prostaglandins (such as PGE2), which results in bone and tissue destruction [4]. During this stage, surgical intervention will be needed to treat the disease. The surgery may include bone or tissue grafts, open flap surgery, tissue regeneration, or tooth …show more content…

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