Lesch-Nyhan Syndrome

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Lesch-Nyhan syndrome is a disease that appears almost entirely in males. It is categorized by neurological and behavioral oddities and the overproduction of uric acid. Uric acid is a waste product of regular chemical processes that are located in blood and urine. Additional uric acid can be discharged from the blood and build up under the skin and cause gouty arthritis (arthritis that is a build up of uric acid in the joints). Uric acid buildup can also cause kidney and bladder stones. The nervous system and behavioral disorders experienced by people with Lesch-Nyhan syndrome contain irregular unintentional muscle movements, such as tensing of various muscles (dystonia), jolting movements (chorea), and thrashing of the limbs (ballismus). Persons with Lesch-Nyhan syndrome usually cannot walk, require aid sitting, and commonly use a wheelchair. Self-injury (including biting and head banging) is the most common and is a very distinct behavioral problem in patients with Lesch-Nyhan syndrome.
The most usual displayed characteristic is developmental delay throughout the first year of life, with hypotonia and late motor skill maturity usually apparent by age three to six months. Kids with Lesch-Nyhan syndrome fail to reach normal milestones that include walking, sitting by themselves and crawling. Growth and puberty are also full-fledged at later times than normal children. If symptoms are appropriately coped with, most individuals survive into their twenties or thirties. There may be a slower advancement of disease in adulthood. Overall in the United States, Lesch-Nyhan syndrome affects 1 and 380,000 people. According to worldwide tests, the disease has the same frequency in each population and is not apparent more in a specific ethni...

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...at have it battle hard and try their hardest to live the most normal life possible.

Works Cited

Kaneshiro, Neil K. "Lesch-Nyhan Syndrome: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, 16 May 2012. Web. 15 Jan. 2014. http://www.nlm.nih.gov/medlineplus/ency/article/001655.htm
2.) "Lesch-Nyhan Syndrome." - Genetics Home Reference. U.S. National Library of Medicine, 13 Jan. 2014. Web. 14 Jan. 2014. .
3.) Jinnah, H. A. "Lesch-Nyhan Disease ." Lesch-Nyhan Disease. WebMD, 13 Dec. 2013. Web. 15 Jan. 2014. .
4.) Draper, Richard. "Patient.co.uk - Trusted Medical Information and Support." Patient.co.uk. EMIS, 17 Sept. 2010. Web. 14 Jan. 2014. .

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