Legionella pneumophila
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Introduction:
Legionella pneumophila are gram-negative rods. They are very difficult to culture because of their complex nutrient requirements, such as cysteine, high concentrations of iron, and the use of activated charcoal agar. They survive as intracellular pathogens of either protozoa or human macrophages. They are most often found in stagnant water reservoirs like air conditioning cooling towers, whirlpool spas, humidifiers, faucets and shower heads, and are infectious when inhaled. L. pneumophila was first identified and named after the American Legion convention of 1976, held in Philadelphia, PA. 182 people became infected, and 29 died (most of which were older men or cigarette smokers). Although this organism was named in the 70’s, retrospective studies showed cases since 1943.
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Diseases:
L. pneumophila has a very wide range of effects. Healthy individuals usually go through an asymptomatic seroconversion, while less healthy people may undergo Pontiac Fever or Legionnaires’ Disease (LD). In 1968, employees at the county health department in Pontiac, Michigan came down with a fever, but the responsible pathogen was not identified at the time. It was frozen and later diagnosed as L. pneumophila. Pontiac Fever, being milder than LD, generally does not need treatment. Infected individuals will show fever, muscle aches, and headaches, and usually recover between 2-5 days. Pontiac Fever will present symptoms anywhere from a couple of hours to a couple of days after exposure, while LD takes 2-10 days to incubate. LD patients have fever, chills and a cough, with x-rays showing pneumonia. This more severe form usually prevails in elderly, cigarette smokers, people with chronic lung disease, or those who are immunocompromised, such as cancer or AIDS patients.
Virulence:
Being a gram-negative bacterium, L. pneumophila has lipopolysaccharides (LPS) that act as endotoxin within a human host. The presence of a flagella is thought to mediate adherence to human lung cells, thereby causing infection, since flagella-less strains do not cause disease. Once attached to human cells, the organism is engulfed by a macrophage where is utilizes the internal environment to multiply.
Symptoms, which include diarrhea and abdominal pain, usually begin two to eight days after a person has been exposed to the bacteria and resolve within a week.
Studies have shown pertactin, a 69kDa non fimbrial outer membrane protein, facilitates attachment of the bacteria to ciliated respiratory cells. Experiments conducted on humans to test the role of pertactin have shown no significant effect except with the results from Bassinet (4). Furthermore, filamentous haemagglutinin confers infection by attaching to the host cells in the lower respiratory tract. It is about 2nm wide, and 50n...
"Bloodborne Pathogens : MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 09 Feb. 2014.
Marriages during the Renaissance shared common customs such as “crying of the banns” ceremonies, a dowry or gift for the husband’s family, special clothes, and a wedding feast. Commonly, marriages were arranged although Shakespeare’s was not. William Shakespeare and Anne Hathaway followed some traditional wedding customs and disregarded others.
“Pleasantville” Conflicts and clashes of all sizes occur throughout the movie. The conflicts cover a wide variety of subjects, from sexual morals to discovering something new about one’s own self. The movie plays out individual struggles along with tying these conflicts in with a larger story line. The setting of the story is a 1990’s family. The parents are divorced, the son is a TV watching geek and the daughter is rebellious and popular at school. The Mom is leaving for a weekend trip, Jennifer, the daughter, has a date that night and David plans an evening home watching ...
"Master of Science in Speech-Language Pathology (2-Year Program).” College of Health & Rehabilitation Sciences: Sargent College. Boston University.
In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.
It’s interesting to know that clinics like the one I volunteer for are approved by the Department of Education and can provide additional services to children who need them. I have been told by quite a few people that in the past, speech-language pathologists had to know a little bit of everything, and while that still holds true today, specialized speech-language pathologists are becoming more of the norm. The American Speech-Language-Hearing Association offers SLPs the opportunity to receive their Clinical Specialty Certification, which is a step beyond the Certificate of Clinical Competence. These areas include Child Language and Language Disorders, Fluency and Fluency Disorders, Swallowing and Swallowing Disorders, and Intraoperative Monitoring; Auditory Verbal Therapy (AVT), what the SLP that worked with Student A was certified in, is governed by the Alexander Graham Bell Academy for Listening and Spoken Language. As a future speech-language pathologist, I will be able to refer a child whose speech and language issues go beyond hearing loss to the appropriate SLP and work collaboratively with him/her; educators will be able to advocate for their
Marriage in the Victorian time period was carefully contemplated, as Rosenberg addresses that “Wedding ceremonies were seen as an expression of Victorian social values that that the Queen wished to renounce, while on the other hand, such occasions were viewed as having national and collective significance” (Rosenberg 98). Love played a very tiny role in the Victorian Era marriages. An engagement was more approached as a business deal. Once married all possessions went to the husband as property. Anatolyevna emphasizes how “Victorian weddings should be transformed from a formalized procedure to a celebration, a holiday for a young couple in honor of their initiation” (Anatolyevna 1) The Marriage and Wedding Customs of the Victorian time period are interesting because they are religious, strict, unique, and elegant. First of all, the Victorian time period wedding mores were intriguing because of their strong connection to religion. Terpening explains that “in the sense that marriage is an act through hardship and trial, people who led Christian lives were rewarded by enjoying years with their spouse” (Terpening 22). Even though in the Victorian time period their marriages were arranged, if you and your spouse had the same religions beliefs your marriage will be strong and last longer than other couples. People during the Victorian time believed that if you didn’t practice the same beliefs of your partner your marriage would fall apart or be in great bitterness. Religion played a big role in the Victorian wedding ethnicities but the harsh laws of marriage were a huge part for weddings during this time period. Next, the Victorian time period Wedding traditions were remarkable because of the firm traditions. Author Kat Stromquist ment...
The pneumonic plague is transmitted through any form of infection. There is one to three days inc...
Like every aspect in Victorian society, great expectations were placed upon weddings. In fact, during this time frame, several guidebooks for weddings were referred to, one of these books was “Our Deportment: On the Manners and Conduct and Dress of the Most Refined Society” by John H. Young. Many traditions regarding weddings first took place during the Victorian Age and are still followed today.
Have you ever thought about how we talk and what causes us to say those words the way we say them? Well a speech pathologist does. Their entire job focuses on how and what causes people to speak the way they do. Most people have no problem with speaking but some do. There are several disorders in speech, one being stuttering. Most people do not understand the importance and the difficulty of learning how to cope with the disorder of stuttering. This speech disorder can affect numerous aspects in a patients’ life and can cause embarrassment, or even possibly lower some people’s self-confidence level; to some people stuttering isn’t just an aspect in their life, their life revolves around the disorder and trying to overcome it. When dealing with stuttering it takes identifying the disorder and making sure the patient is being affected by stuttering, also figuring out what will help the individual cope with the side effects of stuttering, and explaining the importance of overcoming this disorder in a stutterer’s daily life.
"Marriage in Elizabethan Times - Nothing But Shakespeare." Marriage in Elizabethan Times - Nothing But Shakespeare. N.p., n.d. Web. 28 Apr. 2014.
Audiologists, C. A.-L. (2012, October). Early Identifacation of Speech adn Language Disorders. Retrieved from CASLPA: http://www.caslpa.ca
Nestlé Company based in Switzerland is the largest food company in the world and makes 1.8 million USD per day just from selling bottled water, non sparkling bottled water being its most profitable commodity. Nestlé has plants of bottled water across the United States and around the world. Nestlé controls one-third of the US market and sells water under 70 different brands across the world. Some popular ones are- Deer Park, Nestlé Pure Life, Ozarka, Ice Mountain and Poland Spring.