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Function of lipids chemistry
Lipids biological importance
Function of lipids chemistry
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A macromolecule is defined as a “cell which joins smaller organic molecules together to form larger molecules”. There are four macromolecules which enables the structure and function of life to occur, which includes carbohydrates, lipids, proteins and nucleic acids. Out of the three macromolecules, carbohydrates, proteins and nucleic acids, they form a chainlike molecular structure called “polymers”, linked together by covalent bonds such as a “dehydration reaction” (removing a water molecule and forming a new bond) and “hydrolysis” (adding the water molecule and breaking a bond). These polymers range in variety and can be built from a small set of monomers, 40-50 common monomers and other rarer ones, composed in various combinations.
The reason
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In nucleic acids, they are the building blocks for life, consisting of “genes” which allows the process of gene expression to occur.
A lipid is a “compound(s) based on fatty acids or closely related compounds such as the corresponding alcohols and the sphingosine bases” (Gunstone , 1996). They contribute to the survival of an organism by its use to store energy and insulate the body, which is necessary. These lipids that controls this are known as “triacylglycerol” (also called triglycerol).
Triacylglycerol is mainly composed of glycerol and fatty acids. Glycerol is an alcohol, containing a “carbon atom carrying two CH2OH (hydroxyl) groups” (Gunstone , 1996). Fatty acids contain an 18 or 16 carbon atom skeleton, having a hydrocarbon chain and carboxyl group on the skeleton. A triacylglycerol is constructed from a dehydration reaction from a OH molecule and a OH molecule, in fatty acids. This results in an Ester linkage between the carboxyl group and the hydroxyl group, and the formation of either solid triacylglycerol (fats) or liquid triacylglycerol (oils). Due to the “relatively non-polar C-H bond in the hydrocarbon chains of fatty acids” (Reece, et al., 2011) they are
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James Watson and Francis Crick, the discoverers of the 3-D structure of the double helix, concluded this, which was further concluded by the experiments of Erwin Chargaff. Chargaff acknowledged that the “number of adenine and thymine relative to the number of guanine and cytosine” (Bruice, 2007) are unique and different from one species to another. DNA allows the replication of its own material and most importantly guides RNA
Fatty acids such as linoleic acid, linolenic acid and arachidonic acid are known as essential fatty acid because they cannot be synthesized in the body so must be supplied in the food. Human being lacks the ability to introduce double bonds in fatty acids beyond carbons 9 & 10. About 20 different fatty acids are synthesized from the two essential fatty acids linoleic acid and linolenic acid. Omega three fatty acid is synthesized from linolenic acid and omega six fatty acid is synthesized from linolic acid.
In April of 1953, James Watson and Francis Crick published a game changing paper. It would blow the mind of the scientific community and reshape the entire landscape of science. DNA, fully knows as Deoxyribonucleic Acid is the molecule that all genes are made of. Though it is a relatively new term with regard to the age of science, the story of DNA and the path to its discovery covers a much broader timeframe and had many more contributors than James Watson and Francis Crick. After reading the paper the audience should have a better understanding of what DNA is, the most important experiments that contributed to its ultimate discovery and the names and contributions of the lesser-known scientists that helped Watson and Crick turn their idea
The Structure and Function of Carbohydrates Large biological molecules are called macromolecules, there are giant molecules (polymers) made up of repeating units (monomers). Carbohydrates are one of the main classes of biological molecules. Macromolecule units (monomers) are joined together by condensation reactions and hydrolysis reactions split macromolecules down into their individual units. Carbohydrates are molecules that contain elements of carbon, hydrogen, and oxygen. Carbohydrates have a 2:1 hydrogen to oxygen ratio, there are twice as many hydrogen atoms as oxygen atoms (the same proportion as in water).
The first and primary contribution to solving the DNA structure was the relationship of Crick and Watson. Without their teamwork and determination, another scientist would have discovered the structure before them. One of Crick’s bigger contributions was discovering the gene is self-replicating. After talking with John Griffith, Crick came up with the idea that the gene is self-replicating, meaning the gene has the ability “to be exactly copied when the chromosome number doubles during cell division”(126). With further discussion with Griffith, Francis believed that DNA replication involved specific attractive forces between the flat surfaces of the bases (128). One of Watson’s major contributions was after seeing the B form of DNA by Franklin, Watson knew that the structure of DNA was two-chained and that led to the building of the model of DNA (171). Also through research, Watson became aware that adenine and thymine pair together and are held by two hydrogen bonds that were identical in shape to the guanine and cytosine pair held together by at least two hydrogen bonds (194). This discovery showed that the two chains of DNA are complementary to each other. With these individual contributions coming together, Watson and Crick successfully were able to piece together the structure of DNA.
Fats: Fats or lipids are important in diet to provide the body with energy. The British Nutrition Foundation state that fats are made up of amino acids. There are two types of fats they are saturated and unsaturated. Saturated fats are solid at room temperature such as cheese, butter etc. Too much saturated fats increase the risk of heart disease. Whereas unsaturated fats are liquid at room temperature such as nuts, vegetable oil etc. These maintain healthy cholesterol levels.
plants and adorable little animals, have you ever wondered what makes all living things? Lipids are
Unsaturation fatty acid chains with one double bond present is a monounsaturated fatty acid, but if it contains two or more double bonds in the carbon chain of a fatty acid it is a polyunsaturated. In the chain, the two carbon atoms, which are bound next to each side of the double bond, can occur in a cis or trans configuration (figure 2). Saturated fat tends to raise blood cholesterol levels. Unlike saturated fats, most unsaturated fats are good and tends to lower LDL cholesterol. However, the trans-fat is an exception of that because it is generally considered to be bad for the person's health. The temperature when the molecule melts affected by The degree of unsaturation of the fatty acids in a fat. Mostly, the more saturated a fat, the more solid and firmer its consistency, so largely saturated animal fats are solid. In contrast, it remains more liquid at room temperature if it more unsaturated a fat. Therefore, vegetable oils that containing monounsaturated or polyunsaturated fatty acids
The omega-3 fatty acids, popularly referred to as fish oil, are considered unsaturated fats. Science differentiates between unsaturated and saturated fats quite clearly. One fact that separates the two is the temperature at which melting occurs. Saturated fats melt at a higher temperature than unsaturated fats. The science behind fatty acids is rather complex; carboxylic acids with long hydrocarbon chains are the building blocks of saturated and unsaturated fats. This is important to the human body for many reasons; one reason being unsaturated fats do not cause plaque build-up in arteries like saturated fats due to their molecular structure in the human blood stream.
Monounsaturated fats have a single carbon-to-carbon double bond resulting in two fewer hydrogen atoms than a saturated fat and are responsible in keepings monounsaturated fats liquid at room temperature. Some sources of monounsaturated fats are olive oil, peanut oil, canola oil, avocado oil and most nut oils, as well as high-oleic safflower and sunflower oils. A study carried out in the
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
DNA is composed of three major factors: a five-carbon sugar, a phosphate group, and nitrogenous bases (Biology pg. 259-260). The first major factor is the five-carbon sugar, which is a sugar molecule known as deoxyribose. The second major factor is phosphate group, which acts as a type of backbone and allows the DNA, as well as RNA, the opportunity to form the long chains of nucleotides “by the process of dehydration synthesis (Biology pg. 260).” The third main component is the nitrogenous bases, which can be a purine group, or a two-ringed structure; or a pyrimidine, which is a single-ringed structure.
There are many more lipids than I have mentioned in my research paper, there are over a 100 know lipids. Lipids are very important for our body and cells and they carry out many function. They provide nutrients for our body. Lipids are a category of nutrients. Lipids consist of fats, oils, and waxes and are very important for are body’s health. Lipids are important for the human body because they are for storing energy, they’re good at storing energy because they can concentrate a group of calories in a smaller area. Lipids are also used to make soaps, detergents and waxes. These are things that we use in every day life.
The Double Helix tells a tale of fierce competition, perseverance, and scientific innovation as we follow James Watson and his cohort Francis Crick on their quest to discover the secret to life, the structure of deoxyribonucleic acid. Although already fascinated with DNA, Watson struggled with finding chemistry exciting enough to learn it in depth. He had studied birds in college and thereby managed to avoid any formal chemistry or physics courses. As he later pursued a PhD in biochemistry, he realized he could put it off no longer and attempted to learn organic chemistry at Indiana University. However, after a mishap in the lab, he was encouraged instead to study nucleic acid chemistry with Herman Kalckar in Copenhagen. There, his mind strayed from his work and he began doing unauthorized research in the lab of Ole Maaløe, studying phages. Herman stopped teaching Watson after going through a divorce with his wife, and sent Watson off to a scientific conference in Naples. Although he was bored by many of the lectures, Maurice Wilkins’s talk about X-ray diffraction fascinated Watson. He was struck by an X-ray diffraction picture of DNA that Maurice presented and was determined to study the acid. He later got to know more about Maurice’s colleague, Rosalind Franklin, who was proud, stubborn, and very difficult to work with. Watson greatly admired the lecture given by the renowned Linus Pauling, who had discovered the structure of the alpha-helix and was thought of as the leader in DNA research in the scientific world.
Discoveries in DNA, cell biology, evolution, and biotechnology have been among the major achievements in biology over the past 200 years, with accelerated discoveries and insight’s over the last 50 years. Consider the progress we have made in these areas of human knowledge. Present at least three of the discoveries you find to be the most important and describe their significance to society, health, and the culture of modern life. DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).