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the ethics of gene therapy
the controversy of gene therapy
the ethics of gene therapy
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In this paper, I will argue that genetic therapies should be allowed for diseases and disabilities that cause individuals pain, shorter life spans, and noticeable disadvantages in life. I believe this because everyone deserves to have the most even starting place in life as possible. That is no being should be limited in their life due to diseases and disabilities that can be cured with genetic therapies. I will be basing my argument off the article by “Gene Therapies and the Pursuit of a Better Human” by Sara Goering. One objection to genetic therapies is that removing disabilities and diseases might cause humans to lose sympathy towards others and their fragility (332). However, I do not believe this because there are many other events and conditions in society that spark human compassion and sympathy towards others. First, I must define what types of diseases and disabilities fall under the category of things I believe we should be able to treat with genetic therapies and why. As Goering states, “if a child needs surgery or a painful treatment to survive or to thrive, we allow ourselves room to do what is ‘best for the child’ even if that may involve unavoidable pain that the child is not able to consent to.” If we were to except this as true, then a logical conclusion would be to fix the problem through genetic therapy before a child has to go through any pain. We should save them from these gruesome experiences. Some examples that Goering lists are Tay-Sachs disease, Lesch-Nyan syndrome, and cystic fibrosis (332). There are many other instances of disabilities or diseases that can cause disadvantages in life. Goering lists deafness and color-blindness, but I think that paralysis should also be included in thi... ... middle of paper ... ...sion and sympathy. Genetic therapy will not cause the human race to feel less sympathetic towards others who are in a frail state. I believe that Goering would agree with me. She focuses more on the fact that people will want to remove all pain, i.e. adolescence. She never touches on the fact that there are many other types of suffering that happen every day. There is no way we could ever prevent every event that causes any sort of pain. Basic day-to-day activities, such as walking and eating, can cause pain such as stubbing your toe or burning your tongue. We will always have daily pain and suffering, but genetic therapy can get rid of long-term pain and suffering caused by diseases and disabilities. For these reasons, Goering would agree with me that humanity would not loose their sympathy and compassion towards others who are more frail then they are.
When James Watson and Francis Crick discovered the structure of DNA in 1959, they could not have known that their discovery would one day lead to the possibility of a human factory that is equipped with the capabilities to mass produce perfectly designed, immortal human beings on a laboratory assembly line. Of course, this human factory is not yet possible; genetic technology is still in its infancy, and scientists are forced to spend their days unlocking the secret of human genetics in hopes of uncovering cures for diseases, alleviating suffering, and prolonging life. In the midst of their noble work, scientists still dream of a world—a utopia—inhabited by flawless individuals who have forgotten death and never known suffering. What would become of society if such a utopia existed? How will human life be altered? Leon Kass, in Life, Liberty and the Defense of Dignity: The Challenge for Bioethics, acknowledges genetics technology’s greatness, and applauds it for its invaluable, benevolent contributions to mankind. However, Kass argues that if left to their devises and ambitions, geneticists—with the power of their technology—will steal away society’s most precious asset; genetic technology will rob society of its humanity. Genetic technology can, and will, achieve great things, but unless it is regulated and controlled, the losses will be catastrophic and the costs will far exceed the benefits.
...ne starts life with an equal chance of health and success. Yet, gene therapy can also be thought of as a straight route towards a dark outlook, where perfection is the first priority, genes are seen as the ultimate puppeteer, and personal freedom to thrive based on one’s self isn’t believed to exist. With the emergence of each new technological discovery comes the emergence of each new ethical debate, and one day, each viewpoint on this momentous issue may be able to find a bit of truth in the other. Eventually, our society may reach a compromise on gene therapy.
Recent breakthroughs in the field of genetics and biotechnology have brought attention to the ethical issues surrounding human enhancement. While these breakthroughs have many positive aspects, such as the treatment and prevention of many debilitating diseases and extending human life expectancy well beyond its current limits, there are profound moral implications associated with the ability to manipulate our own nature. Michael Sandel’s “The Case Against Perfection” examines the ethical and moral issues associated with human enhancement while Nick Bostrom’s paper, “In Defense of Posthuman Dignity” compares the positions that transhumanists and bioconservatists take on the topic of human enhancement. The author’s opinions on the issue of human genetic enhancement stand in contrast to one another even though those opinions are based on very similar topics. The author’s views on human enhancement, the effect enhancement has on human nature, and the importance of dignity are the main issues discussed by Sandel and Bostrom and are the focus of this essay.
Diseases like cancer, AIDS, cardiovascular disease, cystic fibrosis and Alzheimer’s could potentially be cured (American Medical Association). However, serious risks can be associated with gene therapy. If a gene is added to the DNA, there is a possibility it may be inserted in the wrong place, which can lead to other harmful effects (Gene Therapy and Children). However, it also has the ability to positively effect patients lives. Once gene therapy is ready to be practiced in our society, deadly diseases caused by single gene defects will likely be wiped out and the suffering will end. Although this process is nearly perfected in Brave New World, the effects it has in society are endless. They are able to establish social classes by closely monitoring the embryos, “The lower the caste, the shorter the oxygen,” said Mr. Foster (Huxley 14). Although that may seem like torture, the world these people live in believe they are doing it for the well being of each citizen. The Director says, “that is the secret of happiness and virtue – liking what you’ve got to do. All conditioning aims at that: making people like their un-escapable social destiny” (Huxley 16). If our society could figure out how to cure certain genetic diseases, they would also have the ability to make peoples lives a little more
In this paper, I will negatively expose Walter Glannon’s position on the differentially between gene therapy and gene enhancement. His argument fails because gene therapy and genetic enhancement is morally impermissible because its manipulation and destruction of embryos shows disrespect for human life and discrimination against people with disabilities.
To conclude, although gene therapy can cure a wide variety of diseases which cannot be cured by traditional medicine, and patients can get permanent cure without rejections, it can be high-risk and immoral. The negative effects of gene therapy lead to the shrink of the number of volunteers, and many trials have been forced to cease. The Gene therapy's potential to revolutionize medicine in the future is exciting, and hopes are high for its role in curing and preventing childhood diseases.
Lee, Thomas F. “Gene Therapy is Beneficial.” Genetic Engineering: Opposing Viewpoints. Ed. Carol Wekesser. San Diego: Greenhaven Press, Inc., 1996. 166-173.
Wesley J. Smith goes on and on about how eugenicists would want to create homogeneity among Humans, valuing traits such as intelligence and looks instead of love, compassion, and empathy. He feels that this would create an unnatural society of human beings, creating chaos among the world. What he fails to recognize however is that it is not nearly as simple to do this as he thinks. Right now, cloning is in its very elementary stages, and most research being done is for medical purposes. Through advancing our knowledge in cloning and genetic engineering, we can eliminate unwanted traits and genetic diseases. Wesley may then try to argue that these unwanted traits and diseases make us unique, but I doubt he will get much support, especially from somebody who suffers from some horrible genetic disease or deformity.
Since its inception, gene therapy has captured the attention of the public and ethics disciplines as a therapeutic application of human genetic engineering. The latter, in particular, has lead to concerns about germline modification and questions about the distinction between therapy and enhancement. The development of the gene therapy field and its progress to the clinic has not been without controversy. Although initially considered as a promising approach for treating the genetic of disease, the field has attracted disappointment for failing to fulfil its potential. With the resolution of many of the barriers that restricted the progress of gene therapy and increasing reports of clinical success, it is now generally recognised that earlier expectations may have been premature.
John Harris in the article "Is Gene Therapy a Form of Eugenics?" says that there is no moral difference between treating dysfunction and genetic enhancement, where improvement protects life and health. Gene therapy is the treatment of diseases with the help of genes, while eugenics is the science of improving the population of people, by deducing the desired characteristics. John Harris identifies eugenics producing the best offspring. He supports eugenics in those cases when we are talking about the potential life of a child from the life of a potential disability. According to Harris, gene therapy is ethically justified, since improving the qualities will lead to the protection of the future generation. It should be noted that he believes
Gene therapy gives patients who born with diseases that are incurable to traditional medicine a permanent cure. If patients received germ-line therapy, which involves replacing disordered genes in sperms or eggs, their offspring would also have correct gene orders. The positive effect would influence the whole family.
Scientists and the general population favor genetic engineering because of the effects it has for the future generation; the advanced technology has helped our society to freely perform any improvements. Genetic engineering is currently an effective yet dangerous way to make this statement tangible. Though it may sound easy and harmless to change one’s genetic code, the conflicts do not only involve the scientific possibilities but also the human morals and ethics. When the scientists first used mice to practice this experiment, they “improved learning and memory” but showed an “increased sensitivity to pain.” The experiment has proven that while the result are favorable, there is a low percentage of success rate. Therefore, scientists have concluded that the resources they currently own will not allow an approval from the society to continually code new genes. While coding a new set of genes for people may be a benefitting idea, some people oppose this idea.
Advancements in science and medicine are usually accompanied with a myriad of ethical and moral implications. The fairly recent advancement in genetics called gene therapy is no exception to the baggage of polarizing views that come with new technology. Gene therapy is an extremely hot topic in both the science world and everyday life. New technology, discoveries, and breakthroughs are rapidly occurring in the field every day. The topic of gene therapy in humans is one that is highly debated due to the ethical implications connected to the science. Both sides of the debate have various reasons for their position, but the main factors come down to the ethics of changing someone’s genome and the consequences that accompany the altercations. The two types of gene therapy, somatic and germ-line are seen in different lights. There is more debate over germ-line therapy because the alterations have more consequences than somatic gene therapy. There are many moral and ethical decisions that need to be considered before gene therapy can be widely accepted. Do we have the right to change a person’s genetics, especially before they are born? Do we know enough to confidently insert or delete genes without detrimental consequences down the road? If we have the ability to help people who have disabilities or diseases, is it ethical to withhold and not treat the patient? I believe human gene therapy is a good and useful tool for medicine and needs to be developed because it posses the ability to help and cure people from ailments that degrade their quality of life.
Almost everybody knows someone with a genetic disease. An aunt, a daughter, a friend, a coworker, every body is susceptible to have a genetic based disease. There are many types of genetic diseases ranging from skin malformations to lethal heart problems that could cause death. Genetic diseases affect newborns “Of the 3 to 6 percent of newborns with a recognized birth defect, at least half involve a predominantly genetic contribution.” (Fridovich, Fridovich-Kelly &Robinson, 2013, p.1); though there are other diseases such as cancer or aids that are obtained through an individual’s life and a big percentage of people are affected. That is why many scientists have searched for a solution to these problems that have affected so many people. Somatic cell gene therapy is the best cure to treat genetic diseases.