Charcot Marie Tooth Disease Research Paper

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Recommended: Charcot–Marie–Tooth disease

Signs and symptoms
Charcot Marie Tooth disease encompasses a group of inherited disorders that affect motor and sensory peripheral nerves. It is a type of neuropathy characterized by damage to myelin sheaths and nerve axon structure that results in impaired ability of the peripheral nervous system to send signals or relay sensory information. CMT typically presents with distal predominance of limb-muscle wasting, weakness, and sensory loss , . Symptoms start in the feet, which commonly have high arches, hammer toes, intrinsic muscle weakness, and wasting. The disease then begins to affect the legs and the lower thighs, which results in distal atrophy of the lower limbs. The hands become affected, followed by the forearms. Sensory loss also

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