Alzheimer's Informative Speech

Hello, my name is Celine and today, I’m going to talk about Alzheimer’s disease.

This disease was first recorded at 1907 by Dr. Alois Alzheimer. Alzheimer’s is a type of dementia that causes problems with memory, thinking and behavior. Alzheimer’s is not a normal part of aging. The greatest known risk factor is increasing age. The most common early symptom for Alzheimer’s disease is difficulty remembering newly learned information. Scientists are not sure about the cause of the Alzheimer’s disease yet. But they think plaques and neurofibrillary tangles are the cause of damaging and killing nerve cells.

Today, we know that one gene from chromosome 19 called APOE is providing a strong indication of risk for the disease. By 2050, Alzheimer’s will affect 150milioin people in the world. IT is one of the biggest both medical and social challenges of our generation. The disease has been discovered 111 years ago, and we still couldn’t find the cure. Alzheimer’s is in the list of top 10

When synapse happens, neurotransmitters are released. That’s when communication of our brain happens. When two neurons connect, we think, see, hear, desire and remember. But people with less neurotransmitters has will probably have more chance of getting Alzheimer’s disease because their brain isn’t going to communicate with each other that much.

So, what are plaques? They are deposits of a protein fragment called beta amyloid that build up in the spaces between nerve cells. They form when protein pieces called amyloid beta are clumped. A-Beta comes from a larger protein found in the fatty membrane surrounding nerve cell. A-Beta is pretty sticky. The small clumps block cell to cell signaling at synapses. This situation leads to nerve cell death and tissue loss throughout the brain.

Then what are neurofibrillary tangles? They are inside dead and dying cells. They’re made up of twisted strands of protein called