Alzheimer’s is a form of dementia; it affects one’s memory and the ability to complete everyday tasks. In 1906, Alzheimer’s disease was founded by a German physician, Dr. Alois Alzheimer. He had a patient who had experienced a significant amount of memory loss, but not knowing why. In and around the nerve cell in the brain, while studying the patient’s autopsy, he was able to differentiate the deposits that led to the nerve cells and compared to normal brain nerve cells. Dr. Alzheimer has touched many lives with his findings about Alzheimer’s disease. A German Psychiatrist, Emil Kraepelin had worked with Dr. Alzheimer and named this disease after him. By 1968, researchers and doctors started to see the increase in the diagnosis of the disease in older adults. The cureless disease, Alzheimer’s is affecting many elders and their families; it is the sixth leading cause of death in the Unites States (“About Alzheimer’s”). Many researchers and scientists have been trying to find what causes this disease and they have found that it has to do with neurological brain functions or genetics. Alzheimer’s disease falls into two categories: risk genes and deterministic genes. Risk genes are when one may develop the disease but it’s not definite that it will happen. There is one gene that has been identified in the risk genes category called APOE-e4, it is the most common gene for someone who has Alzheimer’s disease (Atkins 45). The other category is called deterministic genes and it is the cause of the disease. If someone in one’s family has this disease, it will increase the chances of one developing the disease. According to the Alzheimer’s association, “ Deterministic genes, which are estimated to account for less than 5 percent of Alzhe... ... middle of paper ... ...usion, aggression, hostility, and uncooperativeness patients can use olanzapine, quetiapine, risperdone and siprasidone. All these drugs have to be used with extreme caution (“About Alzheimer’s”). Alzheimer’s disease is a rapid growing disease that is affecting millions of people around the world. From the discovery of Alzheimer’s disease in 1906 to now, technology has improved in finding the details in the brain and nerve cells. Research centers and doctors are working together to find the cure and other treatments to relieve the symptoms. It’s depressing to see these elders not being able to remember their own family and going through all the pain that this disease causes. Not only does it affect the patient but also the caregivers and/or family around them. Raising awareness for this disease is important so there can be more research done to help find the cure.
The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning signs of Alzheimer’s can be beneficial to both the patient and his family. Finally, once the patient has been diagnosed as having Alzheimer’s, a plan for treatment as well as providing the family and caregivers with a support system can help ease those involved through a very challenging, heartbreaking time.
Alzheimer’s disease is a type of dementia that affects cognitive function in the elderly population. The exact cause of the disease is unknown but may include genetic as well as environmental factors. A progression of specific neurological changes allows the progression of the disease. Short-term memory losses along with dementia are typical symptoms of the disease. A definite diagnosis of the disease currently can only be confirmed by an autopsy. The disease progresses in five stages that will vary with every patient. There is no current acceptable treatment to reverse or stop the progression of the disease.
of diagnosis is about 80 years old (Johnson, 1989). The incidence is about the same for all races, but women are more likely than men to develop the disease, because they live longer. The second factor is heredity. Family history plays a role in about forty percent of people with early onset of Alzheimer’s (Johnson, 1989). If your parents or a sibling developed the disease, you are more likely to, as well. But there are cases of families with several people who have had this disease and other members are not affected. These two factors are the only proven factors, but environmental research is being done to help with a possible protective effect for the disease. As of now, more research is needed to confirm any be...
Alzheimer’s disease was first postulated by the Bavarian psychiatrist by the name of Alois Alzheimer in 1906, however very little was known about the illness (Selkoe). Today, it is well documented that Alzheimer’s disease is the leading cause of the mental disorder known as dementia. Furthermore, dementia affects an estimated 25 million people in the world (Dalvi). The National Institute of Aging, under the purview of the U.S. Department of Health and Human Services defines Alzheimer’s disease as “an irreversible, progressive brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks.” Alzheimer’s disease, like most diseases, has levels of severity and get worse of the course of time. In early or “mild” stage of Alzheimer’s disease, the person might start exhibiting issues that could include “wandering and getting lost, trouble handling money and paying bills, repeating questions, taking...
As with any disease there are factors that may put one at more risk for developing the disease. The most common risk factor is age. After 65, the likelihood of developing Alzheimer’s disease doubles every 5 years - this means as you age you are more likely to be diagnosed with Alzheimer’s. Although, in early onset, people can be diagnosed as early as in their thirties - there are 500,000 people in America living with early onset Alzheimer’s. Being female is another risk factor. Women are more likely than men to be living with Alzheimer’s. Two-thirds of people living with Alzheimer’s in America are women. Another risk factor is genetic predisposition or family history. Some avoidable risk factors involve head injury and heart health...
In the modern age scientists and researchers are constantly discovering new diseases and disorders that affect the human body. With technology improving and new equipment being introduced it enables scientists to gain more knowledge about the disorders than ever before. During the last century a German physician by the name of Alois Alzheimer linked a patient’s memory loss to her brain autopsy which displayed signs of brain shrinkage. His discovery is now known today as Alzheimer’s disease; which is a form of dementia and is a psychological disease that causes the brain to deteriorate. In today’s day and age, there are still many unanswered questions about Alzheimer’s disease (Crider, A., Goethals, G., Kavanough, R., & Solomon, P. 1989). A few known facts are that Alzheimer’s disease is it is most commonly found in elderly humans, with majority of carriers being age 60 or older. It is important to note that Alzheimer’s disease is not an old person’s disease and that it can also be found in adults of younger ages. Furthermore, there are two forms of Alzheimer’s disease. The two forms are called Early-onset which is found in adults ages 30-59 and Late-Onset which is more common and occurs in adults ages 60 and up. Alzheimer’s disease may not be curable, however with the right information it can be easy to conquer (Alzheimer and Dementia Resources).
Alzheimer’s disease is a fatal neurodegenerative disease that becomes more prevalent with age. Discovered by German psychologist Alois Alzheimer in 1906, it is associated with a memory loss, speech impediment, and dementia. In Canada alone, 500,000 people suffer from this terrible disease and the number of cases is predicted to double by 2031[7]. Worldwide, nearly 44 million people are believed to be experiencing Alzheimer’s disease and every 68 seconds, someone in the United States of America develops Alzheimer’s [8]. Alzheimer’s disease is also the sixth leading cause of death in North America. Furthermore, it is the only leading cause of death that is still increasing in prevalence. Not only fatal, Alzheimer’s is also severely crippling for all the friends and family that are affected by the patient. The memory loss and dementia that is directly linked to Alzheimer’s disease can cause the patient to forget the identity of their loved ones. For the people that have known the patient for many years, this can be very devastating. The long and terrible journey from an able-bodied and functioning member of society to a barely self-sufficient person is not a pleasant one. Undoubtedly, Alzheimer’s disease needs to be cured not only for those suffering from the affliction, but for their loved ones who have to endure the fateful journey as well.
Currently there is no cure for Alzheimer’s, scientists have also tried to increase the time for which the disease can fully take over the nerve cell connections, however that to cannot be achieved present-day, sometimes if the disease is caught early on it can be slowed down, but it is very rare. They are however developing treatments that may help with the symptoms. Out of about 7 billion people in the world, 300 million are American and the Alzheimer's Association states that, “More than 5 million Americans have Alzheimer's disease today” (Stone, “Genetics and Alzheimer's”).
Alzheimer's disease is the most common form of dementia, and this terminal, progressive brain disorder has no known cause or cure. Its greatest known risk factor is increasing age which is why is it is infamous for developing in the elderly, typically in ages 65 or over, however for the 5%(1) that develop Alzheimer’s in their 40s or 50s it is known as early Alzheimer’s. Because Alzheimer’s worsens over time, those with it tend to struggle with completing daily tasks especially elderly people. Given that there is no cure for Alzheimer’s, the treatments available slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer’s and their caregivers. It is not known what causes Alzheimer's, however, those with Alzheimer's have been found to have abnormal amounts of protein (amyloid plaques) and fibres.(The amyloid plaques and fibres are found in regions of the brain where problem solving and thinking take place e.g The cerebrum.) Due to the unusual amounts of amyloid plaques and fibres, it reduces the effectiveness of healthy neurons and eventually, destroying them.
Alzheimer’s disease comes from the last name of a neuro-psychiatrist from Germany, Alois Alzheimer. The disease was first diagnosed when a woman in her early fifties began experience memory problems. “Alzheimer recounted the now famous case of ‘Auguste D.’ a 51-year-old housewife who had been failing mentally for several years. As a result she had been admitted to his care in the Asylum for the Insane and Epileptic…” (Maurer and Maurer 1). After her death, he continued to examine her brain to find causes and explanations for her behavior. He discovered “…classic neuro-pathological signs of plaques and tangles” (Maurer and Maurer 1). “Plaques are chains of amino acids that are pieces of the amyloid precursor protein…tangles are aggregates of the protein tau” (Secko 1). As plaques develop they produce tangles and “these two abnormalities ultimately lead to loss of cognitive function” (Secko 1) Alois Alzheimer’s research has allowed many specialist to conclude that the apolipoproetein E gene may contribute to the disease.
In 1906, a German physician named Dr. Alois Alzheimer dealt with a patient that had been battling severe memory and confusion problems and had tremendous difficulty understanding questions and basic functions. Alzheimer suspected that the ailment had more to it than inherent memory loss. During an autopsy of the brain, he discovered that there were deposits of neuritic plaques surrounding the nerve cells and twisted fibers, known as neurofibrillary tangles, inside of the nerve cells. These observations became the definitive diagnosis of Alzheimer’s disease. The plaques and tangles that develop are a natural part of aging; however, they develop far more aggressively in Alzheimer’s victims. The plaques and tangles then block communication among nerve cells and disrupt the cells processes, eventually killing them. This destruction causes memory failure, personality changes, and problems carrying out everyday functions. Alzheimer’s especially attacks the memory. A victim in the later stage of the disease can...
Thesis/Preview Statement – Alzheimer’s disease (AD) causes a decline in brain function, it destroys healthy nerve cells. Today, we have discussed Causes, Symptoms, and Diagnosis of AD.
Alzheimer’s disease was discovered in 1906 by German physician Alois Alzheimer. While studying the biopsy of the brain of a fifty-five year old woman who had suffered some type of severe dementia, he noticed some aberrations in her brain structure. The brain appeared shrunken, with enlarged crevasses in the gray matter. Over a century later, we now know that Alzheimer’s is caused by a mixture of chemical and cellular brain abnormalities and the breaking down of cells in the mind. Most of the defects occur in the cerebral cortex, which is the outer gray matter of the brain and the center of most human-like brain functions like memory, language, and thought.
One cause of Alzheimer’s disease is high blood pressure. High blood pressure weakens the humans arteries which leads to strokes, and can cause dementia along with Alzheimer’s. Another cause is the shrinking of the brain due to brain cells dying leading to this disease. Genetics is one of the main causes of having this disease from it running through your family. The three main factors are age, family history, and genetics. The death of cells in the brain mainly causes this disease in the body. Alzheimer’s is a genetic mutation that is passed on to children and down the line in families that are affected by it or have Alzheimer’s disease. Many factors influence this particular disease such as head trauma, heart-head connection, and general health aging.
Alzheimer’s is present in over 40 million individuals worldwide, with over 5 million being in the United States. Various organizations and institutions, such as the G8, have begun referring to Alzheimer’s as an epidemic, and one who experts fear could affect over 100 million people by the 2020’s. As of today, Alzheimer’s disease is the 6th leading cause of death in the United States and will only continue killing as the lifespan of U.S. citizens continues to rise. While many hopeful researchers are aiming to have a sound cure and or treatment for Alzheimer’s soon, the grim truth of the matter is that as of today millions are being plagued by this disease with no true curative treatments available.