Chemotherapy: Will There Ever Be an End

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“You have cancer.” Those few words, uttered from a doctor’s mouth, can break hearts and change lives. The century old fear of cancer still survives in the hearts and minds of those whose lives and families have been affected by this tragic disease. With modern medicines more and more people are surviving the many different types of cancer, but the fear of the disease is still very prominent. Surgery, radiation, and chemotherapy are just a few of the treatments used to treat cancer. Surgery is used to remove small tumors that have not yet spread through the body. Afterwards radiation is used to control the smaller tumor growths that could not be removed during surgery. Chemotherapy, often just called ‘chemo’, is used to destroy the cancer that has spread or that can’t be reached surgically or by a radiation therapy (“History of Cancer”). It has saved many people’s lives by destroying the cancer in their bodies. Chemo is like life, it had a beginning, it has a middle, and hopefully one day the need for chemotherapy will end.

Chemotherapy was first discovered during World War II when naval personnel, who had been exposed to mustard gas, were found with toxic changes in their bone marrow cells. During the war, “the US Army was studying chemicals related to mustard gas to develop more effective agents for war and also develop protective measures.” This research led to the discovery of a compound called nitrogen mustard (“History of Cancer). Two pharmacologists, Louis Goodman and Alfred Gilman, used nitrogen mustard to treat a patient who had non-Hodgkin’s lymphoma. The tumor masses of the patient regressed, but “this remission, however, lasted only a few weeks, and disease again progressed, but the principle was establis...

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