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Exercise and disease prevention
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Atherosclerosis is a major form of cardiovascular disease which occurs through a processed known as arteriosclerosis in which the arteries become clogged with plaque buildup overtime. Formation of this plaque is due to the damage of endothelial cells (inner cells) that line the walls of arteries. Damage of these cells is triggered by unhealthy practices or other conditions such as smoking, lack of exercise, hypertension, diabetes or high cholesterol levels. As a result harmful material such as fat, cholesterol, palettes and other material deposit themselves into the damaged artery wall. These materials accumulate and form plaque which becomes covered with various cells that try to repair the damaged wall. These cells encapsulate the plaque within the artery wall and eventually secrete chemicals which cause plaque to build up further. The narrowing effect of this buildup within the arterial wall obstructs blood circulation and increases the risk for stroke or heart attack as blood clots can be trapped within the narrowed artery.
According to an online article from the University of Ma...
LDL or bad cholesterol comes from food that is a high source of cholesterol and/or saturated fats. Plaque forms when bad or LDL cholesterol builds up in your bloodstream and attaches to the arterial wall, as more LDL builds up the plaque becomes larger, this can become a major problem for your cardiovascular system. Because plaque is a substance that has rough edges, it reduces the elastic nature of the artery which means your heart will have to work double-time to pump the necessary blood to all your limbs, that will mean your limbs won’t get the amount of oxygen that they require to function properly. Plaque can also narrow the area blood has to pass through, this means your heart has to work overtime and overall capacity of your cardiovascular system is lowered. When the LDL cholesterol embeds itself in the wall of the artery it than damages the artery then blood pressure expands it which causes an aneurysm. When an aneurysm is too weak there is a high possibility of it bursting, when that happens it leaves the cells in and around that area without oxygen. If that artery is connected to a major vital organ the person will most likely die. When the blood flow is slowed it shows a greater risk for blood clots and although blood clots are natural and important to healing broken blood vessels, if blood clots gather inside the blood vessel this proves to be a serious health risk. The clots have the possibility to get stuck and completely cut off the blood flow to cells, leaving them without oxygen and causing them to die. If a clot gets inside a blood vessel connected to a major organ this could cause the person to die. The heart is fed by the coronary artery, if plaque or a blood clot blocks off blood flow to the heart, the heart ...
Atherosclerosis begins when the inner wall of the artery becomes damaged and cholesterol and fatty plaques begin to lodge in the arteries. Damage to the endothelial wall inside the artery can be caused by hypertension, hyperlipidemia, and hyperglycemia (“Subclinical Atherosclerosis..” 443). When this happens, the immune system responds by sending monocytes to the damaged area. The monocytes turn into macrophages; their job is to eat up the excess cholesterol and unblock the artery. The macrophages are unable to digest all of the cholesterol, and as a result turn in to foam cells. When many macrophages are turned into foam cells, plaque results, and protrudes into the arterial wall, restricting blood flow and raising blood pressure (“Atherosclerosis Growth Process.” 8). If the plaque becomes too large it may break, releasing plaque into the blood. This can cause a great reduction in blood flow or a clot, resulting in stroke or myocardial infarction (“Stroke Risk.” 3).
Peripheral Arterial Disease is most commonly a result of atherosclerosis, the narrowing and hardening of the arteries. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque can build up and harden and narrow the arteries. This limits blood flow throughout the body. PAD occurs if plaque builds up in the major arteries that supply oxygen-ri...
Coronary artery disease (CAD) is the most common type of multifactorial chronic heart disease. It is a consequence of plaque buildup in coronary arteries. The arterial blood vessels, which begin out smooth and elastic become narrow and rigid, curtailing blood flow resulting in deprived of oxygen and nutrients to the heart [1].
Coronary heart disease is defined by the hardening of the epicardial coronary arteries. The buildup of plaque in the arteries slowly narrows the coronary artery lumen. In order to better understand the physiology of the disease, it is important to first know the basic anatomy of the human heart. The aorta, located in the superior region of the heart, branches off into two main coronary blood vessels, otherwise known as arteries. The arteries are located on the left and right side of the heart and span its surface. They subsequently branch off into smaller arteries which supply oxygen-rich blood to the entire heart (Texas Heart Institute, 2013). Therefore, the narrowing of these arteries due to plaque buildup significantly impairs blood flow throughout the heart.
Atherosclerosis is the culprit behind coronary heart disease (CHD) and stroke, which is the most common cause of death worldwide and in the United States10. Among the modifiable risk factors of CHD and stroke is the serum low density lipoprotein level (LDL)8, 11. Several randomized clinical trials have established that reducing the serum LDL level results in a reduction in the future risk of CHD and stroke in a linear relationship, in one study it was estimated that reducing the LDL by 1 % would reduce the risk by 1.7 %.1-4, 7, 9, 13
What is a Myocardial Infarction? Myocardial Infarction, also known as a heart attack, occurs when there is a blockage in one of the coronary arteries. The heart is a muscle that needs oxygenated blood and nutrients to survive. When a blockage occurs in the arteries, oxygen and nutrients are cut off from the heart for an extensive time. The blocked portion of tissue in heart dies. Blockages can occur due to several factors. Coronary artery disease is the most prevalent cause. Coronary artery disease or atherosclerosis is due to plaque buildup and narrowing in the artery walls. These plaques are made from cholesterol and waste products. This buildup on artery walls can restrict blood flow; a process that can take
Smooth muscle cells proliferate at the site of damage and then lipids and cholesterol are deposited from the blood. The cholesterol deposited in the walls may be attacked by free radicals released by phagocytes which may slow down the passage of low density lipoproteins which carry cholest... ... middle of paper ... ... flated balloon is attached to a fine catheter and inserted into the partially blocked artery.
Heart Disease You need your heart for all your body needs. It pumps about 2000 gallons of blood a day. It takes about 20 seconds for blood to reach every cell in the body. An artery that carries blood out of the heart.
Atherosclerosis is the most common cause of CAD. Atherosclerosis is a progressive disease characterized by fat deposits in the arteries causing them to block the normal passage of blood. No one is quite sure how atherosclerosis develops. The plaque consists mostly of cholesterol, phospholipids and smooth muscle cells. They also reduce the size of the lumen of the affected artery which impairs the blood flow of this artery and later on could form a thrombus that will completely occlude the vessel. “Unfortunately, signs and symptoms of atherosclerosis usually don’t develop until at least 70% of an artery’s lumen has become obstructed. Angina is almost always the first symptom to appear.”(Journal: The killer behind CAD,2010). Modifiable factors that could prevent the occurrence of CAD include cigarette smoking, obesity, physical inactivity, atherogenic diet like diet high in cholesterol, use of contraceptive and hormone therapy replacement. “Women continue to ...
Coronary Heart Disease Coronary heart disease is the most common form of heart disease. It is a general term for both heart attack and angina. Many people suffer from it and 500,000 Americans die from it each year. It is much more common in older people and in males. However, women tend to be older and sicker when they are first treated for a heart attack.
Cardiovascular disease is developed by a build-up of fatty deposits on the inner walls of the blood vessels, which typically takes years to accrue (World Health Organization). The development of the fatty-acid deposits can occur due to an unhealthy diet, physical inactivity, tobacco use, and a harmful intake of alcohol. The behavioral risk factors listed above account for about 80% of cardiovascular disease, with the other 20% being cause by fixed risk factors (age, gender, race).
of fatty substances on the inside wall of the arteries). It is not caused by
Cardiovascular disease (CVD) refers to the dysfunctional conditions of the heart, arteries, and veins that supply oxygen to vital life- sustaining areas of the body like the brain, the heart itself and other vital organs. Since the term cardiovascular disease refers to any dysfunction of the cardiovascular system there are many different diseases in the cardiovascular category, and many of these diseases are strongly intertwined. Ischemic Heart Disease is the medical idiom for the obstruction of blood flow to the heart. It is usually due largely in part to excess fat or plaque deposits that narrow the veins that provide oxygenated blood to the heart. This excess fat buildup and plaque are respectively known as arteriosclerosis and atherosclerosis. Hypertension is frequently a result of both arteriosclerosis and atherosclerosis, and can lead to more serious CVDs, such as angina attack (an acute and squeezing chest pain due to inefficient blood flow to the heart), and myocardial infarction( the sudden death of part of the heart muscle). A stroke is a CVD that occurs when there is in inadequate oxygen flow to the brain. An abnormally high or abnormally low heart rate because of the disruption of the natural electric impulses of the heart is called cardiac arrhythmia. Carditis and endocarditis, the infection and inflammation of the heart, can occur as a result of a weak immune system, liver problems, heart surgery, or an autoimmune disorder.
High cholesterol is the best known of all the many threats to a healthy heart. When excess amounts fatty like plaque substance build up along the walls of the arteries, you face a significantly higher risk of a complete blockage, leading to a heart attack or stroke. At normal levels, cholesterol is not a bad thing. On the other hand, its an essential material used by the body to make cell walls and produce hormones, such as testosterone and estrogen. The body produces its own supply of cholesterol in the liver, it’s also found in various animal products such as meats, eggs, and, milk. Cholesterol only becomes a threat when the body can’t use or get rid of excessive amounts of it.